Clinical relevance of patient-reported outcome measures in patients who have undergone total hip arthroplasty: a systematic review

Migliorini, Filippo; Maffulli, Nicola; Memminger, Michael Kurt; Simeone, Francesco; Rath, Björn; Huber, Thorsten

Abstract

Introduction
In orthopaedic research, it is crucial to determine changes that are statistically significant and clinically meaningful. One approach to accomplish this is by calculating the Minimal Clinically Important Difference (MCID), the Clinically Important Differences (CID), the Minimum Detectable Change (MDC), the Minimal Important Change (MIC), and the Patient Acceptable Symptom State (PASS) values. These tools assist medical professionals in comprehending the patient’s viewpoint, enabling them to establish treatment objectives that align with patients’ desires and expectations. The present systematic review investigated the MCID, MIC, CID, MDC, and PASS of the most used PROMs to assess patients who have undergone THA.

Methods
This systematic review followed the 2020 PRISMA guidelines. Web of Science, Embase, and PubMed were accessed in March 2024 without time constraints or additional filters. All the clinical investigations which evaluated data tools (MCID, MIC, CID, MDC, and PASS) to assess the clinical relevance of PROMs in THA were accessed. Articles in Spanish, Italian, German, and English were eligible. Studies with levels of evidence I to III were eligible.

Results
Data from 100,824 patients were collected. All relevant demographic data were analysed and summarised. In addition, the MCID, MIC, CID, MDC and PASS of the COMI, HOOS, SF-36, OHS, Oxford-12, PROMIS-PF, SF-12, and WOMAC scores for THA were determined.

Conclusion
Current evidence recommends to collect MCIDs based on anchors routinely. These values should be used as complementary tools to determine the clinical effectiveness of a treatment instead of solely relying on statistically significant improvements.

Citation

Migliorini, F., Maffulli, N., Memminger, M. K., Simeone, F., Rath, B., & Huber, T. (in press). Clinical relevance of patient-reported outcome measures in patients who have undergone total hip arthroplasty: a systematic review. Archives of Orthopaedic and Trauma Surgery, https://doi.org/10.1007/s00402-024-05579-w

• Journal Article Type: Article
• Acceptance Date: Sep 11, 2024
• Online Publication Date: Sep 24, 2024
• Deposit Date: Oct 4, 2024
• Journal: Archives of Orthopaedic and Trauma Surgery
• Print ISSN: 0936-8051
• Publisher: Springer Verlag
• Peer Reviewed: Peer Reviewed
• DOI: https://doi.org/10.1007/s00402-024-05579-w
• Keywords: Hip; Arthroplasty; Patient-reported outcome measures; PROMs
• Public URL: https://keele-repository.worktribe.com/output/948225
• Publisher URL: https://link.springer.com/article/10.1007/s00402-024-05579-w
• Additional Information: Received: 22 August 2024; Accepted: 11 September 2024; First Online: 24 September 2024; : ; : The authors declare that they have any competing interests in this article.; : This study complies with ethical standards.; : Not applicable.; : Not applicable.; : The present review was not registered.