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What is Karyomapping and where does it fit in the world of preimplantation genetic diagnosis (PGD)? (2017)
Journal Article
(2017). What is Karyomapping and where does it fit in the world of preimplantation genetic diagnosis (PGD)?

The first application of preimplantation genetic diagnosis (PGD) recently celebrated its 25th birthday. Aside from the very early days when chromosomal diagnoses were used (by sexing) for the selective implantation of embryos unaffected by sex linked... Read More about What is Karyomapping and where does it fit in the world of preimplantation genetic diagnosis (PGD)?.

A standard-enabled workflow for synthetic biology. (2017)
Journal Article
Mısırlı, G., Nguyen, T., Oberortner, E., Samineni, M., Wipat, A., Zhang, M., Zundel, Z., Madsen, C., McLaughlin, J., Myers, C., Beal, J., Gorochowski, T., & Kuwahara, H. (2017). A standard-enabled workflow for synthetic biology. Transactions, 793 - 803. https://doi.org/10.1042/BST20160347

A synthetic biology workflow is composed of data repositories that provide information about genetic parts, sequence-level design tools to compose these parts into circuits, visualization tools to depict these designs, genetic design tools to select... Read More about A standard-enabled workflow for synthetic biology..

Symptom experience in non‐dialysis‐dependent chronic kidney disease: A qualitative descriptive study (2017)
Journal Article
Pugh‐Clarke, K., Cheryl Read, S., & Sim, J. (2017). Symptom experience in non‐dialysis‐dependent chronic kidney disease: A qualitative descriptive study. Journal of Renal Care, 43(4), 197-208. https://doi.org/10.1111/jorc.12208

Background
Studies indicate that symptoms attributable to impaired kidney function are important determinants of quality of life and functional status in patients with chronic kidney disease (CKD). Accordingly, symptom assessment and subsequent cont... Read More about Symptom experience in non‐dialysis‐dependent chronic kidney disease: A qualitative descriptive study.

The pathway to consultation for rheumatoid arthritis: exploring anticipated actions between the onset of symptoms and face-to-face encounter with a healthcare professional. (2017)
Journal Article
Mallen. (2017). The pathway to consultation for rheumatoid arthritis: exploring anticipated actions between the onset of symptoms and face-to-face encounter with a healthcare professional. BMC Musculoskeletal Disorders, 258 -?. https://doi.org/10.1186/s12891-017-1619-9

BACKGROUND: When people first experience symptoms of rheumatoid arthritis (RA) they often delay seeking medical attention resulting in delayed diagnosis and treatment. This research assesses behaviours people might engage in prior to, or instead of,... Read More about The pathway to consultation for rheumatoid arthritis: exploring anticipated actions between the onset of symptoms and face-to-face encounter with a healthcare professional..

Mortality after percutaneous coronary revascularization: Prior cardiovascular risk factor control and improved outcomes in patients with diabetes mellitus. (2017)
Journal Article
Mamas, M., & Rashid, M. (2017). Mortality after percutaneous coronary revascularization: Prior cardiovascular risk factor control and improved outcomes in patients with diabetes mellitus. Catheterization and Cardiovascular Interventions, 1195-1204. https://doi.org/10.1002/ccd.26882

OBJECTIVES: To assess the mortality in patients with diabetes mellitus (DM) following percutaneous coronary intervention (PCI) according to their insulin requirement and PCI setting (elective, urgent, and emergency). BACKGROUND: DM is a major risk fa... Read More about Mortality after percutaneous coronary revascularization: Prior cardiovascular risk factor control and improved outcomes in patients with diabetes mellitus..

Preparation and evaluation of PLGA nanoparticle-loaded biodegradable light-responsive injectable implants as a promising platform for intravitreal drug delivery (2017)
Journal Article
Bisht, R., Jaiswal, J. K., Oliver, V. F., Eurtivong, C., Reynisson, J., & Rupenthal, I. D. (2017). Preparation and evaluation of PLGA nanoparticle-loaded biodegradable light-responsive injectable implants as a promising platform for intravitreal drug delivery. Journal of Drug Delivery Science and Technology, 40, 142-156. https://doi.org/10.1016/j.jddst.2017.06.006

The present study reports on the development of a hybrid system by integrating poly(lactic-co-glycolic)acid nanoparticles (PLGA NPs) into light-responsive in-situ forming injectable implants (ISFIs) for minimally invasive and safe intravitreal peptid... Read More about Preparation and evaluation of PLGA nanoparticle-loaded biodegradable light-responsive injectable implants as a promising platform for intravitreal drug delivery.

Spinal muscular atrophy: antisense oligonucleotide therapy opens the door to an integrated therapeutic landscape. (2017)
Journal Article
Wood, M., Talbot, K., & Bowerman, M. (2017). Spinal muscular atrophy: antisense oligonucleotide therapy opens the door to an integrated therapeutic landscape. Human molecular genetics, 26(R2), R151 - R159. https://doi.org/10.1093/hmg/ddx215

Spinal muscular atrophy (SMA) is a devastating neuromuscular disorder characterized by loss of spinal cord motor neurons, muscle atrophy and infantile death or severe disability. It is caused by severe reduction of the ubiquitously expressed survival... Read More about Spinal muscular atrophy: antisense oligonucleotide therapy opens the door to an integrated therapeutic landscape..

Teaching and learning on a transnational education programme: opportunities and challenges for flying faculty in Geography and related disciplines (2017)
Journal Article
Szkornik. (2017). Teaching and learning on a transnational education programme: opportunities and challenges for flying faculty in Geography and related disciplines. Journal of Geography in Higher Education, 521-531. https://doi.org/10.1080/03098265.2017.1337735

Within the context of the internationalization of UK higher education, an increasing number of UK-based institutions are developing collaborative degree programmes with overseas institutions, of which partnerships with institutions in China are the m... Read More about Teaching and learning on a transnational education programme: opportunities and challenges for flying faculty in Geography and related disciplines.

Exploring the suitability and acceptability of peer support for older veterans (2017)
Journal Article
(2017). Exploring the suitability and acceptability of peer support for older veterans. Quality in Ageing and Older Adults, 120 - 130. https://doi.org/10.1108/QAOA-09-2016-0036

Purpose - Informal social support is often sought by veterans to support reminiscence or cope with traumatic memories. However, it can also encourage unhelpful ways of coping, such as avoidance, or may be absent altogether. This project borrowed from... Read More about Exploring the suitability and acceptability of peer support for older veterans.

Association of One-Step Nucleic Acid Amplification Detected Micrometastases with Tumour Biology and Adjuvant Chemotherapy. (2017)
Journal Article
(2017). Association of One-Step Nucleic Acid Amplification Detected Micrometastases with Tumour Biology and Adjuvant Chemotherapy. International Journal of Breast Cancer, 4971096 - ?. https://doi.org/10.1155/2017/4971096

One-step nucleic acid amplification (OSNA) is an intraoperative technique with a high sensitivity and specificity for sentinel node assessment. The aim of this study was to assess the impact of OSNA on micrometastases detection rates and use of adjuv... Read More about Association of One-Step Nucleic Acid Amplification Detected Micrometastases with Tumour Biology and Adjuvant Chemotherapy..

Neuropathic pain in low back-related leg pain patients: What is the evidence of prevalence, characteristics, and prognosis in primary care? A systematic review of the literature. (2017)
Journal Article
Stynes, S., Dunn, K., Foster, N., Konstantinou, K., & Harrisson, S. (2017). Neuropathic pain in low back-related leg pain patients: What is the evidence of prevalence, characteristics, and prognosis in primary care? A systematic review of the literature. Journal of Pain, 1295-1312. https://doi.org/10.1016/j.jpain.2017.04.012

This systematic review synthesizes literature describing prevalence, characteristics and prognosis of low back-related leg pain (LBLP) patients with neuropathic pain in primary care and/or similar settings. Inclusion and exclusion criteria were devel... Read More about Neuropathic pain in low back-related leg pain patients: What is the evidence of prevalence, characteristics, and prognosis in primary care? A systematic review of the literature..

Delivering person-centred holistic care for older people (2017)
Journal Article
(2017). Delivering person-centred holistic care for older people. Quality in Ageing and Older Adults, 157-167. https://doi.org/10.1108/QAOA-05-2016-0019

Purpose: an evaluated case study of the Wellbeing Coordinator (WBC) service in Cheshire (UK). WBCs are non-clinical members of the GP surgery or hospital team who offer advice and support to help people with long-term conditions and unmet social need... Read More about Delivering person-centred holistic care for older people.

The nature of psychology: Reflections on university teachers' experiences of teaching sensitive topics (2017)
Journal Article
(2017). The nature of psychology: Reflections on university teachers' experiences of teaching sensitive topics. Psychology Teaching Review, 4 -14

This paper describes one aspect of a larger scale qualitative study conducted to investigate psychology-specific issues in learning and teaching in higher education. Participants included academic psychologists from across the career spectrum and fro... Read More about The nature of psychology: Reflections on university teachers' experiences of teaching sensitive topics.

The SCUBA-2 Ambitious Sky Survey: a catalogue of beam- sized sources in the Galactic longitude range 120 degrees-140 degrees (2017)
Journal Article
(2017). The SCUBA-2 Ambitious Sky Survey: a catalogue of beam- sized sources in the Galactic longitude range 120 degrees-140 degrees. Monthly Notices of the Royal Astronomical Society, 250 - 260. https://doi.org/10.1093/mnras/stx339

The SCUBA-2 Ambitious Sky Survey (SASSy) is composed of shallow 850-µm imaging using the Submillimetre Common-User Bolometer Array 2 (SCUBA-2) on the James Clerk Maxwell Telescope. Here we describe the extraction of a catalogue of beam-sized sources... Read More about The SCUBA-2 Ambitious Sky Survey: a catalogue of beam- sized sources in the Galactic longitude range 120 degrees-140 degrees.

Constructing Synthetic Biology Workflows in the Cloud (2017)
Journal Article
Misirli. (2017). Constructing Synthetic Biology Workflows in the Cloud. Engineering Biology, 61-65. https://doi.org/10.1049/enb.2017.0001

The synthetic biology design process has traditionally been heavily dependent upon manual searching, acquisition and integration of existing biological data. A large amount of such data is already available from Internet-based resources, but data exc... Read More about Constructing Synthetic Biology Workflows in the Cloud.

Functional attributes of epilithic diatoms for palaeoenvironmental interpretations in South-West Greenland lakes (2017)
Journal Article
McGowan, S., Gunn, H. V., Whiteford, E. J., Anderson, N. J., Jones, V. J., & Law, A. C. (2017). Functional attributes of epilithic diatoms for palaeoenvironmental interpretations in South-West Greenland lakes. Journal of Paleolimnology, 60(2), 273-298. https://doi.org/10.1007/s10933-017-9968-9

Benthic diatoms are commonly used for palaeoenvironmental reconstruction in Arctic regions, but interpretation of their ecology remains challenging. We studied epilithic diatom assemblages from the shallow margins of 19 lakes from three areas (coast-... Read More about Functional attributes of epilithic diatoms for palaeoenvironmental interpretations in South-West Greenland lakes.

Deregulation of miRNAs in malignant pleural mesothelioma is associated with prognosis and suggests an alteration of cell metabolism (2017)
Journal Article
De Santi, C., Melaiu, O., Bonotti, A., Cascione, L., Di Leva, G., Foddis, R., Cristaudo, A., Lucchi, M., Mora, M., Truini, A., Tironi, A., Murer, B., Boldorini, R., Cipollini, M., Gemignani, F., Gasparini, P., Mutti, L., & Landi, S. (2017). Deregulation of miRNAs in malignant pleural mesothelioma is associated with prognosis and suggests an alteration of cell metabolism. Scientific reports, 7, Article ARTN 3140. https://doi.org/10.1038/s41598-017-02694-0

Malignant pleural mesothelioma (MPM) is an aggressive human cancer and miRNAs can play a key role for this disease. In order to broaden the knowledge in this field, the miRNA expression was investigated in a large series of MPM to discover new pathwa... Read More about Deregulation of miRNAs in malignant pleural mesothelioma is associated with prognosis and suggests an alteration of cell metabolism.