Skip to main content

Research Repository

Advanced Search

All Outputs (1185)

Flow-aligned, single-shot fiber diffraction using a femtosecond X-ray free-electron laser. (2017)
Journal Article
(2017). Flow-aligned, single-shot fiber diffraction using a femtosecond X-ray free-electron laser. Cytoskeleton, 472 - 481. https://doi.org/10.1002/cm.21378

A major goal for X-ray free-electron laser (XFEL) based science is to elucidate structures of biological molecules without the need for crystals. Filament systems may provide some of the first single macromolecular structures elucidated by XFEL radia... Read More about Flow-aligned, single-shot fiber diffraction using a femtosecond X-ray free-electron laser..

GPs' attitudes, beliefs and behaviours regarding exercise for chronic knee pain: a questionnaire survey (2017)
Journal Article
Roddy, E., Cottrell, E., Foster, N. E., Porcheret, M., & Rathod, T. (2017). GPs' attitudes, beliefs and behaviours regarding exercise for chronic knee pain: a questionnaire survey. BMJ Open, 7(6), e014999 - ?. https://doi.org/10.1136/bmjopen-2016-014999

OBJECTIVES: The aim of this study was to investigate general practitioners' (GPs) attitudes, beliefs and behaviours regarding the use of exercise for patients with chronic knee pain (CKP) attributable to osteoarthritis. SETTING: Primary care GPs... Read More about GPs' attitudes, beliefs and behaviours regarding exercise for chronic knee pain: a questionnaire survey.

Integrating case finding and initial management for osteoarthritis, anxiety and depression into routine primary care nurse-led long-term condition reviews: results from the enhance pilot trial (2017)
Journal Article
Jinks, C., Nicholls, E., Liddle, J., Healey, E., Evans, A., Chew-Graham, C., …Team, E. (2017). Integrating case finding and initial management for osteoarthritis, anxiety and depression into routine primary care nurse-led long-term condition reviews: results from the enhance pilot trial. Annals of the Rheumatic Diseases, 76(S2), 1433-1433. https://doi.org/10.1136/annrheumdis-2017-eular.2473

Background Co-morbid osteoarthritis (OA), anxiety and depression are undermanaged in primary care yet have significant impact on pain, disability and outcomes of other long-term conditions (LTCs). Objectives To test the feasibility and acceptabili... Read More about Integrating case finding and initial management for osteoarthritis, anxiety and depression into routine primary care nurse-led long-term condition reviews: results from the enhance pilot trial.

What is Karyomapping and where does it fit in the world of preimplantation genetic diagnosis (PGD)? (2017)
Journal Article
(2017). What is Karyomapping and where does it fit in the world of preimplantation genetic diagnosis (PGD)?

The first application of preimplantation genetic diagnosis (PGD) recently celebrated its 25th birthday. Aside from the very early days when chromosomal diagnoses were used (by sexing) for the selective implantation of embryos unaffected by sex linked... Read More about What is Karyomapping and where does it fit in the world of preimplantation genetic diagnosis (PGD)?.

A standard-enabled workflow for synthetic biology. (2017)
Journal Article
Mısırlı, G., Nguyen, T., Oberortner, E., Samineni, M., Wipat, A., Zhang, M., …Kuwahara, H. (2017). A standard-enabled workflow for synthetic biology. Transactions, 793 - 803. https://doi.org/10.1042/BST20160347

A synthetic biology workflow is composed of data repositories that provide information about genetic parts, sequence-level design tools to compose these parts into circuits, visualization tools to depict these designs, genetic design tools to select... Read More about A standard-enabled workflow for synthetic biology..

Symptom experience in non‐dialysis‐dependent chronic kidney disease: A qualitative descriptive study (2017)
Journal Article
Pugh‐Clarke, K., Cheryl Read, S., & Sim, J. (2017). Symptom experience in non‐dialysis‐dependent chronic kidney disease: A qualitative descriptive study. Journal of Renal Care, 43(4), 197-208. https://doi.org/10.1111/jorc.12208

Background Studies indicate that symptoms attributable to impaired kidney function are important determinants of quality of life and functional status in patients with chronic kidney disease (CKD). Accordingly, symptom assessment and subsequent cont... Read More about Symptom experience in non‐dialysis‐dependent chronic kidney disease: A qualitative descriptive study.

The pathway to consultation for rheumatoid arthritis: exploring anticipated actions between the onset of symptoms and face-to-face encounter with a healthcare professional. (2017)
Journal Article
Mallen. (2017). The pathway to consultation for rheumatoid arthritis: exploring anticipated actions between the onset of symptoms and face-to-face encounter with a healthcare professional. BMC Musculoskeletal Disorders, 258 -?. https://doi.org/10.1186/s12891-017-1619-9

BACKGROUND: When people first experience symptoms of rheumatoid arthritis (RA) they often delay seeking medical attention resulting in delayed diagnosis and treatment. This research assesses behaviours people might engage in prior to, or instead of,... Read More about The pathway to consultation for rheumatoid arthritis: exploring anticipated actions between the onset of symptoms and face-to-face encounter with a healthcare professional..

Mortality after percutaneous coronary revascularization: Prior cardiovascular risk factor control and improved outcomes in patients with diabetes mellitus. (2017)
Journal Article
Mamas, M., & Rashid, M. (2017). Mortality after percutaneous coronary revascularization: Prior cardiovascular risk factor control and improved outcomes in patients with diabetes mellitus. Catheterization and Cardiovascular Interventions, 1195-1204. https://doi.org/10.1002/ccd.26882

OBJECTIVES: To assess the mortality in patients with diabetes mellitus (DM) following percutaneous coronary intervention (PCI) according to their insulin requirement and PCI setting (elective, urgent, and emergency). BACKGROUND: DM is a major risk fa... Read More about Mortality after percutaneous coronary revascularization: Prior cardiovascular risk factor control and improved outcomes in patients with diabetes mellitus..

Preparation and evaluation of PLGA nanoparticle-loaded biodegradable light-responsive injectable implants as a promising platform for intravitreal drug delivery (2017)
Journal Article
Bisht, R., Jaiswal, J. K., Oliver, V. F., Eurtivong, C., Reynisson, J., & Rupenthal, I. D. (2017). Preparation and evaluation of PLGA nanoparticle-loaded biodegradable light-responsive injectable implants as a promising platform for intravitreal drug delivery. Journal of Drug Delivery Science and Technology, 40, 142-156. https://doi.org/10.1016/j.jddst.2017.06.006

The present study reports on the development of a hybrid system by integrating poly(lactic-co-glycolic)acid nanoparticles (PLGA NPs) into light-responsive in-situ forming injectable implants (ISFIs) for minimally invasive and safe intravitreal peptid... Read More about Preparation and evaluation of PLGA nanoparticle-loaded biodegradable light-responsive injectable implants as a promising platform for intravitreal drug delivery.

Spinal muscular atrophy: antisense oligonucleotide therapy opens the door to an integrated therapeutic landscape. (2017)
Journal Article
Wood, M., Talbot, K., & Bowerman, M. (2017). Spinal muscular atrophy: antisense oligonucleotide therapy opens the door to an integrated therapeutic landscape. Human molecular genetics, 26(R2), R151 - R159. https://doi.org/10.1093/hmg/ddx215

Spinal muscular atrophy (SMA) is a devastating neuromuscular disorder characterized by loss of spinal cord motor neurons, muscle atrophy and infantile death or severe disability. It is caused by severe reduction of the ubiquitously expressed survival... Read More about Spinal muscular atrophy: antisense oligonucleotide therapy opens the door to an integrated therapeutic landscape..

Teaching and learning on a transnational education programme: opportunities and challenges for flying faculty in Geography and related disciplines (2017)
Journal Article
Szkornik. (2017). Teaching and learning on a transnational education programme: opportunities and challenges for flying faculty in Geography and related disciplines. Journal of Geography in Higher Education, 521-531. https://doi.org/10.1080/03098265.2017.1337735

Within the context of the internationalization of UK higher education, an increasing number of UK-based institutions are developing collaborative degree programmes with overseas institutions, of which partnerships with institutions in China are the m... Read More about Teaching and learning on a transnational education programme: opportunities and challenges for flying faculty in Geography and related disciplines.

Exploring the suitability and acceptability of peer support for older veterans (2017)
Journal Article
(2017). Exploring the suitability and acceptability of peer support for older veterans. Quality in Ageing and Older Adults, 120 - 130. https://doi.org/10.1108/QAOA-09-2016-0036

Purpose - Informal social support is often sought by veterans to support reminiscence or cope with traumatic memories. However, it can also encourage unhelpful ways of coping, such as avoidance, or may be absent altogether. This project borrowed from... Read More about Exploring the suitability and acceptability of peer support for older veterans.

Association of One-Step Nucleic Acid Amplification Detected Micrometastases with Tumour Biology and Adjuvant Chemotherapy. (2017)
Journal Article
(2017). Association of One-Step Nucleic Acid Amplification Detected Micrometastases with Tumour Biology and Adjuvant Chemotherapy. International Journal of Breast Cancer, 4971096 - ?. https://doi.org/10.1155/2017/4971096

One-step nucleic acid amplification (OSNA) is an intraoperative technique with a high sensitivity and specificity for sentinel node assessment. The aim of this study was to assess the impact of OSNA on micrometastases detection rates and use of adjuv... Read More about Association of One-Step Nucleic Acid Amplification Detected Micrometastases with Tumour Biology and Adjuvant Chemotherapy..

Neuropathic pain in low back-related leg pain patients: What is the evidence of prevalence, characteristics, and prognosis in primary care? A systematic review of the literature. (2017)
Journal Article
Stynes, S., Dunn, K., Foster, N., Konstantinou, K., & Harrisson, S. (2017). Neuropathic pain in low back-related leg pain patients: What is the evidence of prevalence, characteristics, and prognosis in primary care? A systematic review of the literature. Journal of Pain, 1295-1312. https://doi.org/10.1016/j.jpain.2017.04.012

This systematic review synthesizes literature describing prevalence, characteristics and prognosis of low back-related leg pain (LBLP) patients with neuropathic pain in primary care and/or similar settings. Inclusion and exclusion criteria were devel... Read More about Neuropathic pain in low back-related leg pain patients: What is the evidence of prevalence, characteristics, and prognosis in primary care? A systematic review of the literature..