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Health Inequality and its link to HbA1c Test Recovery in a Developed Health Economy: In a 'Nearly Post COVID-19' World (2022)
Presentation / Conference
Heald, A., Holland, D., Duff, C. J., Scargill, J., Hanna, F., & Fryer, A. (2022, November). Health Inequality and its link to HbA1c Test Recovery in a Developed Health Economy: In a 'Nearly Post COVID-19' World. Poster presented at Society for Endocrinology BES 2022, Harrogate, United Kingdom

Background: We previously showed that in first 6 months of the UK Covid-19(C19) pandemic >6.6million HbA1c tests were missed, including 1.4million in people with diabetes(DM). Furthermore, C19 more significantly impacts people with DM / socioeconomic... Read More about Health Inequality and its link to HbA1c Test Recovery in a Developed Health Economy: In a 'Nearly Post COVID-19' World.

Is Vaccination Against Covid-19 Associated with Autoimmune Rheumatic Disease Flare? Self-controlled Case Series Analysis Using Data from the Clinical Practice Research Datalink (Aurum) (2022)
Presentation / Conference
Nakafero, G., Grainge, M. J., Card, T., Mallen, C., Nguyen van Tam, J. S., Williams, H. C., & Abhishek, A. (2022, November). Is Vaccination Against Covid-19 Associated with Autoimmune Rheumatic Disease Flare? Self-controlled Case Series Analysis Using Data from the Clinical Practice Research Datalink (Aurum). Paper presented at ACR Convergence 2022, Philadelphia, PA, USA

Background/Purpose: It is unclear whether autoimmune rheumatic disease (AIRD) flares are associated with the recent prior Covid-19 vaccination, and whether the association was influenced by vaccine modality and prior Covid-19 infection. The objective... Read More about Is Vaccination Against Covid-19 Associated with Autoimmune Rheumatic Disease Flare? Self-controlled Case Series Analysis Using Data from the Clinical Practice Research Datalink (Aurum).

A Genome-Wide Association Analysis of 2,622,830 Individuals Reveals New Pathogenic Pathways in Gout (2022)
Presentation / Conference
Merriman, T., Matsuo, H., Takei, R., Leask, M., Topless, R., Shirai, Y., …Major, T. (2022, November). A Genome-Wide Association Analysis of 2,622,830 Individuals Reveals New Pathogenic Pathways in Gout. Presented at ACR Convergence 2022

Background/Purpose: Genome-wide association studies (GWAS) in gout have been relatively small (≤13,179 people with gout) and have provided little insight into the progression from hyperuricemia to gout. We present a gout GWAS that includes 120,282 pe... Read More about A Genome-Wide Association Analysis of 2,622,830 Individuals Reveals New Pathogenic Pathways in Gout.

The Bioimpedance Spectroscopy to Preserve Renal Output (BISTRO) Multicentre Randomised Controlled Trial: Quality of Life and Blood Pressure Outcomes (2022)
Presentation / Conference
Davies, S. J., Zanganeh, M., Solis-Trapala, I., Keane, D. F., Davenport, A., Wilkie, M. E., …Caskey, F. (2022, November). The Bioimpedance Spectroscopy to Preserve Renal Output (BISTRO) Multicentre Randomised Controlled Trial: Quality of Life and Blood Pressure Outcomes. Poster presented at ASN Kidney Week, Orlando, FL, USA

Genetic Determinants of Ultrafiltration With Peritoneal Dialysis (2022)
Presentation / Conference
Stanaway, I. B., Devuyst, O., Perl, J., Lambie, M., Morelle, J., Jarvik, G. P., …Mehrotra, R. (2022, November). Genetic Determinants of Ultrafiltration With Peritoneal Dialysis. Poster presented at Kidney Week, Orlando, Florida

THE IMPACT OF ADHERENCE TO CLINICAL MANAGEMENT GUIDELINES ON THE OUTCOMES OF THE PATIENTS PRESENTING WITH ACUTE UPPER GASTROINTESTINAL VARICEAL BLEED: A UNIVERSITY HOSPITAL EXPERIENCE (2022)
Presentation / Conference
Kesavan, S., Desai, R., Abbasi, A., & Muller, S. (2022, September). THE IMPACT OF ADHERENCE TO CLINICAL MANAGEMENT GUIDELINES ON THE OUTCOMES OF THE PATIENTS PRESENTING WITH ACUTE UPPER GASTROINTESTINAL VARICEAL BLEED: A UNIVERSITY HOSPITAL EXPERIENCE. Poster presented at British Association for the Study of the Liver Annual Meeting

Background Upper gastrointestinal bleeding (UGIB) caused by gastro-oesophageal varices remains a common complication of cirrhosis with 10% mortality despite improvements in care. University Hospitals of North Midlands (UHNM) was identified by the pre... Read More about THE IMPACT OF ADHERENCE TO CLINICAL MANAGEMENT GUIDELINES ON THE OUTCOMES OF THE PATIENTS PRESENTING WITH ACUTE UPPER GASTROINTESTINAL VARICEAL BLEED: A UNIVERSITY HOSPITAL EXPERIENCE.

Speed of recovery of testing for management of diabetes in the aftermath of COVID-19 is slower in areas of greater social deprivation: findings from a UK study (2022)
Presentation / Conference
Holland, D., Heald, A., Hanna, F., Wu, P., & Fry, A. (2022, September). Speed of recovery of testing for management of diabetes in the aftermath of COVID-19 is slower in areas of greater social deprivation: findings from a UK study. Poster presented at 58 th EASD Annual Meeting of the European Association for the Study of Diabetes, Stockholm, Sweden

Background and aims: We have previously shown that, during the first 6 months of the UK COVID-19-associated lockdown, >6.6M HbA1c tests were missed/delayed, including 1.41M missed/delayed in people with diabetes (0.51M in those with suboptimal contro... Read More about Speed of recovery of testing for management of diabetes in the aftermath of COVID-19 is slower in areas of greater social deprivation: findings from a UK study.

Under Pressure - Pharmacist's perceptions of the effects of postgraduate education on their wellbeing: a qualitative study (2022)
Presentation / Conference
O'Byrne, R., White, S., & Chew-Graham, C. (2022, September). Under Pressure - Pharmacist's perceptions of the effects of postgraduate education on their wellbeing: a qualitative study. Paper presented at Pharmacy Education Conference 2022, Stopford Building, Oxford Road, The University of Manchester, UK

Background: A 2019 NHS commission on the mental wellbeing of healthcare postgraduate learners reported research largely focused on doctors in training and identified the need for further research into the wellbeing needs and ways to support wellbein... Read More about Under Pressure - Pharmacist's perceptions of the effects of postgraduate education on their wellbeing: a qualitative study.

The Regulator’s Trilemma (2022)
Presentation / Conference
O'Donovan, N. (2022, September). The Regulator’s Trilemma. Paper presented at Digital Regulation Cooperation Forum, Competition and Markets Authority/Ofcom, Manchester, England, UK

Inequalities in the incidence and management of non-valvular atrial fibrillation in England, 2009 to 2019: Cohort study using electronic health records from general practices (2022)
Presentation / Conference
Ajabnoor, A., Zghebi, S., Parisi, R., Ashcroft, D., Rutter, M., Doran, T., …Kontopantelis, E. (2022, August). Inequalities in the incidence and management of non-valvular atrial fibrillation in England, 2009 to 2019: Cohort study using electronic health records from general practices

Background Atrial fibrillation is an important risk factor for ischaemic stroke and AF incidence is expected to increase. Guidelines recommend using oral anticoagulants (OACs) to prevent the development of stroke. However, studies have reported the f... Read More about Inequalities in the incidence and management of non-valvular atrial fibrillation in England, 2009 to 2019: Cohort study using electronic health records from general practices.

Evaluating the long-term effect of allopurinol use in gout using marginal structural models: A primary care electronic health records study (2022)
Presentation / Conference
Rathod-Mistry, T., Roddy, E., Jordan, K., Mallen, C., & Blagojevic-Bucknall, M. (2022, August). Evaluating the long-term effect of allopurinol use in gout using marginal structural models: A primary care electronic health records study

Background: Allopurinol is intended to be taken for life in the treatment of gout. In UK primary care, treatment is suboptimal with up to 30% of indicated patients being treated within five years of diagnosis and once prescribed allopurinol, treatmen... Read More about Evaluating the long-term effect of allopurinol use in gout using marginal structural models: A primary care electronic health records study.

Real-world effectiveness and persistence of methotrexate versus adalimumab: A comparative study from the British association of dermatologists biologics and immunomodulators register (BADBIR) (2022)
Presentation / Conference
Alabas, O., Mason, K., Yiu, Z., Warren, R., Lunt, M., Smith, C., & Griffiths, C. (2022, August). Real-world effectiveness and persistence of methotrexate versus adalimumab: A comparative study from the British association of dermatologists biologics and immunomodulators register (BADBIR). Paper presented at 38th International Conference on Pharmacoepidemiology and Therapeutic Risk Management (ICPE), Copenhagen, Denmark

Structural Complexity and Performance of Support Vector Machines (2022)
Presentation / Conference
(2022, July). Structural Complexity and Performance of Support Vector Machines. Presented at 2022 International Joint Conference on Neural Networks (IJCNN), Padua, Italy

Support vector machines (SVM) are often applied in the context of machine learning analysis of various data. Given the nature of SVMs, these operate always in the sub-interpolation range as a machine learning method. Here we explore the impact of str... Read More about Structural Complexity and Performance of Support Vector Machines.