All Outputs (1721)

An investigation of magnetic nanoparticle mediated methods for neuro-regeneration (2024)
Thesis
Nahar, T. S. An investigation of magnetic nanoparticle mediated methods for neuro-regeneration. (Thesis). Keele University. https://keele-repository.worktribe.com/output/775525

Conditions such as Parkinsons disease, where specific cell types are affected such as the dopaminergic neurons in the substantia nigra pars compacta, cell transplantation and growth factor therapy could restore function and slow disease progression b... Read More about An investigation of magnetic nanoparticle mediated methods for neuro-regeneration.

New approaches to diagnosing exact recurrent flows embedded in two-dimensional turbulence (2024)
Thesis
Redfern, E. M. New approaches to diagnosing exact recurrent flows embedded in two-dimensional turbulence. (Thesis). Keele University. https://keele-repository.worktribe.com/output/775657

Turbulent flow is often viewed as a trajectory wandering through a high dimensional phase-space, momentarily visiting the neighbourhood of unstable invariant solutions, e.g. unstable periodic orbits, travelling waves and equilibria. Periodic orbit th... Read More about New approaches to diagnosing exact recurrent flows embedded in two-dimensional turbulence.

Why groups don’t forgive: refining the contributions of ingroup identity, ingroup attachment, justice concerns, and conflict type to intergroup forgiveness (2024)
Thesis
Dinnick, I. Why groups don’t forgive: refining the contributions of ingroup identity, ingroup attachment, justice concerns, and conflict type to intergroup forgiveness. (Thesis). Keele University. https://keele-repository.worktribe.com/output/775650

Researchers have begun to investigate the role of forgiveness in disrupting intergroup conflict and promoting peace. This thesis has refined our understanding of the ingroup identity and forgiveness relationship by determining which ingroup identity... Read More about Why groups don’t forgive: refining the contributions of ingroup identity, ingroup attachment, justice concerns, and conflict type to intergroup forgiveness.

Political attitudes and social change: The role of intergroup contact and social identity complexity (2024)
Thesis
Kızık, B. Political attitudes and social change: The role of intergroup contact and social identity complexity. (Thesis). Keele University. https://keele-repository.worktribe.com/output/775323

This thesis explores the impact of intergroup contact on political attitudes via social identity complexity (SIC) across WEIRD and non-WEIRD societies, including post-conflict contexts. This research aims to test whether and how dimensions of intergr... Read More about Political attitudes and social change: The role of intergroup contact and social identity complexity.

Comprehensive utilisation of hydrogen gas for the efficient use of proton exchange membrane fuel cell powered vehicles (2024)
Thesis
Latham-Wheawall, L. Comprehensive utilisation of hydrogen gas for the efficient use of proton exchange membrane fuel cell powered vehicles. (Thesis). Keele University. https://keele-repository.worktribe.com/output/775441

The need for clean energy is not being met and is increasing each day. One immensely underused technology – proton exchange membrane fuel cells, can drastically help to deliver green energy and prevent the worsening of climate change. However, in ord... Read More about Comprehensive utilisation of hydrogen gas for the efficient use of proton exchange membrane fuel cell powered vehicles.

Understanding the barriers, facilitators and extent of diagnostic delay in axial spondyloarthritis (2024)
Thesis
Hay, C. A. Understanding the barriers, facilitators and extent of diagnostic delay in axial spondyloarthritis. (Thesis). Keele University. https://keele-repository.worktribe.com/output/775300

Background: Axial spondyloarthritis (axSpA) causes inflammation of the pelvis and spine, resulting in chronic pain, impaired range of movement, fatigue and physical disability. Diagnosis remains challenging and is frequently delayed, resulting in poo... Read More about Understanding the barriers, facilitators and extent of diagnostic delay in axial spondyloarthritis.

Recreating arterial thrombosis models using tissue-engineered arterial constructs: A method to reduce and replace mice used in platelet research (2023)
Thesis
Ranjbar, J. A. Recreating arterial thrombosis models using tissue-engineered arterial constructs: A method to reduce and replace mice used in platelet research. (Thesis). Keele University. https://keele-repository.worktribe.com/output/674551

Intravital microscopy in mice is widely used to study in vivo thrombus formation, however, the relevance of these studies to human physiology is unclear. In this thesis, a 3D tissue-engineered human arterial construct (TEAC) was developed that replic... Read More about Recreating arterial thrombosis models using tissue-engineered arterial constructs: A method to reduce and replace mice used in platelet research.

The role of physiotherapy in polymyalgia rheumatica in the United Kingdom: a mixed method study (2023)
Thesis
O'Brien, A. V. The role of physiotherapy in polymyalgia rheumatica in the United Kingdom: a mixed method study. (Thesis). Keele University. https://keele-repository.worktribe.com/output/674475

Background: Polymyalgia Rheumatica (PMR) is the commonest rheumatic condition affecting older people, typically treated with glucocorticoids. However, the treatment side-effects including fatigue, anxiety and other alterations in mood, are frequent a... Read More about The role of physiotherapy in polymyalgia rheumatica in the United Kingdom: a mixed method study.

Hydrodynamic simulations of convection and nucleosynthesis in the late phases of massive stars to constrain and guide stellar evolution theory (2023)
Thesis
Rizzuti, F. Hydrodynamic simulations of convection and nucleosynthesis in the late phases of massive stars to constrain and guide stellar evolution theory. (Thesis). Keele University. https://keele-repository.worktribe.com/output/674565

The present knowledge of stellar evolution is still limited today by large uncertainties that derive from the complex multi-dimensional processes occurring in stars. Among them, the turbulent motions of the stellar fluid control the size and evolutio... Read More about Hydrodynamic simulations of convection and nucleosynthesis in the late phases of massive stars to constrain and guide stellar evolution theory.

FTIR Spectroscopy for cancer diagnosis. How can glass substrates be used to bring it closer to clinical practice? (2023)
Thesis
Dowling, L. M. M. FTIR Spectroscopy for cancer diagnosis. How can glass substrates be used to bring it closer to clinical practice?. (Thesis). Keele University. https://keele-repository.worktribe.com/output/674513

Cancer incidence rates are increasing world-wide including in the UK. An increase in cancer cases puts further pressure on pathology departments that are often already struggling to meet targets to diagnose cancers in a timely manner. Delays in diagn... Read More about FTIR Spectroscopy for cancer diagnosis. How can glass substrates be used to bring it closer to clinical practice?.

Characterising the molecular consequences of LMNA mutations in congenital muscular dystrophy (2023)
Thesis
Storey, E. C. Characterising the molecular consequences of LMNA mutations in congenital muscular dystrophy. (Thesis). Keele University. https://keele-repository.worktribe.com/output/674333

LMNA-related congenital muscular dystrophy (L-CMD) is a rare disorder predominantly causing muscle weakness and wasting, over time, leading to development of dysphagia and life-threating respiratory insufficiency, and sometimes cardiac arrhythmias. T... Read More about Characterising the molecular consequences of LMNA mutations in congenital muscular dystrophy.

Unravelling the immunomodulatory effect of Poly (glycolic acid) particles using new techniques (2023)
Thesis
Xie, B. Unravelling the immunomodulatory effect of Poly (glycolic acid) particles using new techniques. (Thesis). Keele University. https://keele-repository.worktribe.com/output/674529

Non-degradable and biodegradable implants inevitably generate debris or degradation products in the body, and these induce acute and chronic inflammation. Polyglycolic acid (PGA) is a simple linear aliphatic polyester with a wide set of medical appli... Read More about Unravelling the immunomodulatory effect of Poly (glycolic acid) particles using new techniques.

Lay, professional, and police rape stereotype acceptance in England and Wales: A holistic, mixed-methods overview of the Criminal Justice System (2023)
Thesis
Hermolle, M. F. V. Lay, professional, and police rape stereotype acceptance in England and Wales: A holistic, mixed-methods overview of the Criminal Justice System. (Thesis). Keele University. https://keele-repository.worktribe.com/output/674588

This thesis examined rape stereotype acceptance and use in England and Wales, viewed through the lens of Social Representations Theory (SRT). Given the high attrition rate and low prosecution rate for rape, the project was a holistic look at stereoty... Read More about Lay, professional, and police rape stereotype acceptance in England and Wales: A holistic, mixed-methods overview of the Criminal Justice System.

The dynamics of star formation in the local Milky Way as traced by OB associations (2023)
Thesis
Quintana Isasi, A. L. P.-H. The dynamics of star formation in the local Milky Way as traced by OB associations. (Thesis). Keele University. https://keele-repository.worktribe.com/output/598066

OB associations are gravitationally unbound, low-density groups of young stars delineated by bright OB stars. At the intersection of star formation and Galactic structure, they are important across many areas of astronomy. However, most historical OB... Read More about The dynamics of star formation in the local Milky Way as traced by OB associations.

Modelling and forecasting oil market volatility: A regime switching GARCH MIDAS approach (2023)
Thesis
Tirkishova, M. Modelling and forecasting oil market volatility: A regime switching GARCH MIDAS approach. (Thesis). Keele University. https://keele-repository.worktribe.com/output/598023

In this thesis, we consider a regime switching GARCH MIDAS model with Student-t innovations. By allowing the error term to be non-Gaussian, we want to see how effective it is in describing the volatility displayed in financial time series. For the lo... Read More about Modelling and forecasting oil market volatility: A regime switching GARCH MIDAS approach.

Part 1 - Scenes from the Storm Andrew Jackson - The Road to the Presidency A Drama. Part 2 - The Story of the Storm: Issues of History, Genre, and Truth in Scenes from the Storm (2023)
Thesis
Mousinho, G. A. Part 1 - Scenes from the Storm Andrew Jackson - The Road to the Presidency A Drama. Part 2 - The Story of the Storm: Issues of History, Genre, and Truth in Scenes from the Storm. (Thesis). Keele University. https://keele-repository.worktribe.com/output/597519

‘Andrew Jackson, I am given to understand, was a patriot and a traitor. He was one of the greatest of generals, and wholly ignorant of the art of war. A writer brilliant, elegant, eloquent, and without being able to compose a correct sentence, or spe... Read More about Part 1 - Scenes from the Storm Andrew Jackson - The Road to the Presidency A Drama. Part 2 - The Story of the Storm: Issues of History, Genre, and Truth in Scenes from the Storm.

Best interests decisions for people with advanced dementia: a qualitative study of nurses’ perspectives in England (2023)
Thesis
Murphy, J. S. C. Best interests decisions for people with advanced dementia: a qualitative study of nurses’ perspectives in England. (Thesis). Keele University. https://keele-repository.worktribe.com/output/597559

In the United Kingdom (UK), there are 907,900 people aged over 65 with dementia, 546,500 of whom would be classed as having severe dementia (Wittenberg et al 2019). Advanced dementia is now recognised as a leading cause of death in the UK and across... Read More about Best interests decisions for people with advanced dementia: a qualitative study of nurses’ perspectives in England.

Primary care prescribing of orlistat medication for weight management in adults with type 2 diabetes: an epidemiological study (2023)
Thesis
Ghosal, S. Primary care prescribing of orlistat medication for weight management in adults with type 2 diabetes: an epidemiological study. (Thesis). Keele University. https://keele-repository.worktribe.com/output/597570

Introduction
The incidence of type 2 Diabetes mellitus (T2DM) is increasing and is a major public health burden. Obesity is one of the main modifiable risk factors for T2DM. However no UK studies have assessed the relationship of orlistat, a medica... Read More about Primary care prescribing of orlistat medication for weight management in adults with type 2 diabetes: an epidemiological study.

Investigating the use of marine-derived glycosaminoglycans as mimetics for heparan sulphate in fibroblast growth factor signalling (2023)
Thesis
Chen, S. Investigating the use of marine-derived glycosaminoglycans as mimetics for heparan sulphate in fibroblast growth factor signalling. (Thesis). Keele University. https://keele-repository.worktribe.com/output/598060

Fibroblast growth factors (FGFs) are polypeptide growth factors and are potent regulators of cell proliferation, cell differentiation, cell migration and angiogenesis (Ornitz and Itoh, 2001). FGFs can bind with fibroblast growth factor receptors with... Read More about Investigating the use of marine-derived glycosaminoglycans as mimetics for heparan sulphate in fibroblast growth factor signalling.

Using the solid injection technique with gas chromatography and mass spectrometry to identify cuticular hydrocarbons in several thrips insect species (2023)
Thesis
Covaci, A.-D. Using the solid injection technique with gas chromatography and mass spectrometry to identify cuticular hydrocarbons in several thrips insect species. (Thesis). Keele University. https://keele-repository.worktribe.com/output/597582

Thrips are a group of insects included in the order Thysanoptera. So far, over 6000 species have been described, among which over 100 are known as crop pests There is a plethora of studies on various species of thrips, yet the CHC composition is know... Read More about Using the solid injection technique with gas chromatography and mass spectrometry to identify cuticular hydrocarbons in several thrips insect species.