Research "push", long term-change, and general practice
(2015)
Journal Article
All Outputs (1205)
The distribution of blow fly (Diptera: Calliphoridae) larval lengths and its implications for estimating post mortem intervals (2015)
Journal Article
The length or stage of development of blow fly (Diptera: Calliphoridae) larvae may be used to estimate a minimum postmortem interval, often by targeting the largest individuals of a species in the belief that they will be the oldest. However, natural... Read More about The distribution of blow fly (Diptera: Calliphoridae) larval lengths and its implications for estimating post mortem intervals.
Annotation of rule-based models with formal semantics to enable creation, analysis, reuse and visualization. (2015)
Journal Article
MOTIVATION: Biological systems are complex and challenging to model and therefore model reuse is highly desirable. To promote model reuse, models should include both information about the specifics of simulations and the underlying biology in the for... Read More about Annotation of rule-based models with formal semantics to enable creation, analysis, reuse and visualization..
Caveolae as a target to quench autoinduction of the metastatic phenotype in lung cancer (2015)
Journal Article
Purpose Mevalonate pathway inhibitors are potentially useful chemotherapeutic agents showing growth inhibition and pro-apoptotic effects in cancer cells. The effects of statins and bisphosphonates on cancer growth are attributed to a reduction in pr... Read More about Caveolae as a target to quench autoinduction of the metastatic phenotype in lung cancer.
Exhaled breath hydrogen cyanide as a marker of early Pseudomonas aeruginosa infection in children with cystic fibrosis (2015)
Journal Article
Hydrogen cyanide is readily detected in the headspace above Pseudomonas aeruginosa cultures and in the breath of cystic fibrosis (CF) patients with chronic (P. aeruginosa) infection. We investigated if exhaled breath HCN is an early marker of P. aeru... Read More about Exhaled breath hydrogen cyanide as a marker of early Pseudomonas aeruginosa infection in children with cystic fibrosis.
A better participant experience using sms for real time data collection (2015)
Journal Article
High quality, error free and complete data is the Holy Grail for healthcare researchers. Using SMS, researchers can build a data collection pathway which, when integrated with web technologies, can provide a dynamic data collection experience for... Read More about A better participant experience using sms for real time data collection.
An empirical evaluation of the impact of missing data on treatment effect (2015)
Presentation / Conference
Objectives Missing data represent a potential source of bias in randomized clinical trials (RCTs). A simple approach that makes use of the responses subsequently obtained via reminder is proposed to assess the validity of the inferences from a missi... Read More about An empirical evaluation of the impact of missing data on treatment effect.
Reviewing the evidence supporting predictive biomarkers in European medicines agency indications and contraindications using visual plots (2015)
Journal Article
Objectives Predictive biomarkers can be used to identify most suitable treatments for patients. To maximise patient benefit valid predictive biomarkers need to be used and several trial designs have been proposed to achieve this. We aimed to revi... Read More about Reviewing the evidence supporting predictive biomarkers in European medicines agency indications and contraindications using visual plots.
Innovation methods for optimising clinical trial recruitment and retention within primary care (2015)
Journal Article
Background Recruiting patients to research and collecting study data in a primary care setting, combined with maximising retention rates from a primary care population can be challenging and requires recruitment and retention methods which are innov... Read More about Innovation methods for optimising clinical trial recruitment and retention within primary care.
Causal evidence that intrinsic beta frequency is relevant for enhanced signal propagation in the motor system as shown through rhythmic TMS (2015)
Journal Article
Correlative evidence provides support for the idea that brain oscillations underpin neural computations. Recent work using rhythmic stimulation techniques in humans provide causal evidence but the interactions of these external signals with intrinsic... Read More about Causal evidence that intrinsic beta frequency is relevant for enhanced signal propagation in the motor system as shown through rhythmic TMS.
2dF-AAOmega spectroscopy of massive stars in the Magellanic Clouds: The north-eastern region of the Large Magellanic Cloud⋆⋆⋆ (2015)
Journal Article
We present spectral classifications from optical spectroscopy of 263 massive stars in the north-eastern region of the Large Magellanic Cloud. The observed two-degree field includes the massive 30 Doradus star-forming region, the environs of SN1987A,... Read More about 2dF-AAOmega spectroscopy of massive stars in the Magellanic Clouds: The north-eastern region of the Large Magellanic Cloud⋆⋆⋆.
Picomolar Inhibition of Plasmepsin V, an Essential Malaria Protease, Achieved Exploiting the Prime Region (2015)
Journal Article
Malaria is an infectious disease caused by Plasmodium parasites. It results in an annual death-toll of ~ 600,000. Resistance to all medications currently in use exists, and novel antimalarial drugs are urgently needed. Plasmepsin V (PmV) is an essent... Read More about Picomolar Inhibition of Plasmepsin V, an Essential Malaria Protease, Achieved Exploiting the Prime Region.
Disclosing the results of the invasive cervical cancer review to patients: a survey of lead colposcopists across England (2015)
Journal Article
Objective: To survey lead colposcopists to explore the extent to which patients are currently being invited to discuss the results of their invasive cervical cancer review, the reasons why this might not be happening and the clinician experience. Met... Read More about Disclosing the results of the invasive cervical cancer review to patients: a survey of lead colposcopists across England.
Respecting the Voices of Children and Young People in Participatory Action Research. (2015)
Presentation / Conference
A participatory action research (PAR) PhD study is being conducted to critically explore the issues surrounding children visiting adult patients in a large UK hospital. The primary objectives are to increase understanding of how staff could be better... Read More about Respecting the Voices of Children and Young People in Participatory Action Research..
An analysis of business phenomena and austerity narratives in the arts sector from a new materialist perspective (2015)
Journal Article
The paper adopts a lens of new materialism to analyse narratives of managers in the arts sector in response to the master narrative of austerity and proposed‘solutions’ using business models(including accounting). It explores the complex trajectories... Read More about An analysis of business phenomena and austerity narratives in the arts sector from a new materialist perspective.
An analysis of business phenomena and austerity narratives in the arts sector from a new materialist perspective (2015)
Journal Article
The paper adopts a lens of new materialism to analyse narratives of managers in the arts sector in response to the master narrative of austerity and proposed ‘solutions’ using business models (including accounting). It explores the complex trajectori... Read More about An analysis of business phenomena and austerity narratives in the arts sector from a new materialist perspective.
The JCMT Plane Survey: early results from the l=30 degrees field (2015)
Journal Article
We present early results from the JCMT (James Clerk Maxwell Telescope) Plane Survey (JPS), which has surveyed the northern inner Galactic plane between longitudes = 7? and = 63? in the 850-µm continuum with SCUBA-2 (Submm Common-User Bolometer Arra... Read More about The JCMT Plane Survey: early results from the l=30 degrees field.