A Tailor-Made Synthetic Polymer for Cell Encapsulation: Design Rationale, Synthesis, Chemical-Physics and Biological Characterizations

Gerges, Irini; Tamplenizza, Margherita; Rossi, Eleonora; Tocchio, Alessandro; Martello, Federico; Recordati, Camilla; Kumar, Deepak; Forsyth, Nicholas R.; Liu, Yang; Lenardi, Cristina

doi:10.1002/mabi.201500386

All Outputs (3)

Pluripotent and Multipotent Stem Cells Display Distinct Hypoxic miRNA Expression Profiles (2016)
Journal Article

MicroRNAs are reported to have a crucial role in the regulation of self-renewal and differentiation of stem cells. Hypoxia has been identified as a key biophysical element of the stem cell culture milieu however, the link between hypoxia and miRNA ex... Read More about Pluripotent and Multipotent Stem Cells Display Distinct Hypoxic miRNA Expression Profiles.

Mesenchymal stem cell derived products attenuate cytokine-induced apoptosis in pancreatic beta cells (2016)
Presentation / Conference

Aims:Cytokine-driven beta cell apoptosis is central to Type 1diabetes. Mesenchymal stem cells (MSCs) are multipotent cellswith significant immunomodulatory capacity, which counteractautoimmunityand enhance islet engraftment and survival. The aimof th... Read More about Mesenchymal stem cell derived products attenuate cytokine-induced apoptosis in pancreatic beta cells.

A Tailor-Made Synthetic Polymer for Cell Encapsulation: Design Rationale, Synthesis, Chemical-Physics and Biological Characterizations (2016)
Journal Article

This study presents a custom-made in situ gelling polymeric precursor for cell encapsulation. Composed of poly((2-hydroxyethyl)methacrylate-co-(3-aminopropyl)methacrylamide) (P(HEMA-co-APM) mother backbone and RGD-mimicking poly(amidoamine) (PAA) moi... Read More about A Tailor-Made Synthetic Polymer for Cell Encapsulation: Design Rationale, Synthesis, Chemical-Physics and Biological Characterizations.