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Effect of x-ray energy on the radiological image quality in propagation-based phase-contrast computed tomography of the breast (2021)
Journal Article
Wan, S., Arhatari, B. D., Nesterets, Y. I., Mayo, S. C., Thompson, D., Fox, J., …Taba, S. T. (2021). Effect of x-ray energy on the radiological image quality in propagation-based phase-contrast computed tomography of the breast. Journal of Medical Imaging, 8(05), https://doi.org/10.1117/1.jmi.8.5.052108

Purpose: Breast cancer is the most common cancer in women in developing and developed countries and is responsible for 15% of women’s cancer deaths worldwide. Conventional absorption-based breast imaging techniques lack sufficient contrast for compre... Read More about Effect of x-ray energy on the radiological image quality in propagation-based phase-contrast computed tomography of the breast.

Operator Volumes and In-Hospital Outcomes: An Analysis of 7,740 Rotational Atherectomy Procedures From the BCIS National Database. (2021)
Journal Article
Mamas. (2021). Operator Volumes and In-Hospital Outcomes: An Analysis of 7,740 Rotational Atherectomy Procedures From the BCIS National Database. JACC. Cardiovascular interventions, 1423 - 1430. https://doi.org/10.1016/j.jcin.2021.04.034

OBJECTIVES: The aims of this study were to use a national percutaneous coronary intervention (PCI) registry to study temporal changes in procedure volumes of PCI using rotational atherectomy (ROTA-PCI), the patient and procedural factors associated w... Read More about Operator Volumes and In-Hospital Outcomes: An Analysis of 7,740 Rotational Atherectomy Procedures From the BCIS National Database..

Squaramide‐Based Self‐Associating Amphiphiles for Anion Recognition (2021)
Journal Article
Kumawat, L. K., Wynne, C., Cappello, E., Fisher, P., Brennan, L. E., Strofaldi, A., …Elmes, R. B. P. (2021). Squaramide‐Based Self‐Associating Amphiphiles for Anion Recognition. ChemPlusChem, 86(8), 1058-1068. https://doi.org/10.1002/cplu.202100275

The synthesis and characterisation of two novel self‐assembled amphiphiles (SSAs) SQS‐1 and SQS‐2 are reported. Both compounds, based on the squaramide motif, were fully soluble in a range of solvents and were shown to undergo self‐assembly through a... Read More about Squaramide‐Based Self‐Associating Amphiphiles for Anion Recognition.

Developing a New Strategy for Delivery of Neural Transplant Populations Using Precursor Cell Sprays and Specialized Cell Media (2021)
Journal Article
Woods, W. A., Chowdhury, F., Tzerakis, N., Adams, C. F., & Chari, D. M. (2021). Developing a New Strategy for Delivery of Neural Transplant Populations Using Precursor Cell Sprays and Specialized Cell Media. Advanced NanoBiomed Research, 1(9), 2100051 - 2100051. https://doi.org/10.1002/anbr.202100051

Neural precursor/stem cell transplantation therapies promote regeneration in neurological injuries, but current cell delivery methods have drawbacks. These include risks with surgical microinjection (e.g., hemorrhage, embolism) and high cell loss wit... Read More about Developing a New Strategy for Delivery of Neural Transplant Populations Using Precursor Cell Sprays and Specialized Cell Media.

Opportunistic diagnosis of osteoporosis, fragile bone strength and vertebral fractures from routine CT scans; a review of approved technology systems and pathways to implementation (2021)
Journal Article
Aggarwal, V., Maslen, C., Abel, R., Bhattacharya, P., Ward, K., Poole, K., …Bromiley, P. (2021). Opportunistic diagnosis of osteoporosis, fragile bone strength and vertebral fractures from routine CT scans; a review of approved technology systems and pathways to implementation. Therapeutic Advances in Musculoskeletal Disease,

Osteoporosis causes bones to become weak, porous and fracture more easily. While a vertebral fracture is the archetypal fracture of osteoporosis, it is also the most difficult to diagnose clinically. Patients often suffer further spine or other frac... Read More about Opportunistic diagnosis of osteoporosis, fragile bone strength and vertebral fractures from routine CT scans; a review of approved technology systems and pathways to implementation.

Improving outcomes for patients hospitalised with gout: a systematic review. (2021)
Journal Article
Roddy. (2021). Improving outcomes for patients hospitalised with gout: a systematic review. Rheumatology, 90-102. https://doi.org/10.1093/rheumatology/keab539

OBJECTIVES: Hospital admissions for gout flares have increased dramatically in recent years, despite widely available, effective medications for the treatment and prevention of flares. We conducted a systematic review to evaluate the effectiveness an... Read More about Improving outcomes for patients hospitalised with gout: a systematic review..

The attitudes towards, and beliefs about, physical activity in people with osteoarthritis and comorbidity: A qualitative investigation (2021)
Journal Article
McKevitt, S., Jinks, C., Healey, E. L., & Quicke, J. G. (2022). The attitudes towards, and beliefs about, physical activity in people with osteoarthritis and comorbidity: A qualitative investigation. Musculoskeletal Care, 20(1), 167-179. https://doi.org/10.1002/msc.1579

OBJECTIVE: To investigate the attitudes towards, and beliefs about, physical activity (PA) in older adults with osteoarthritis (OA) and comorbidity to understand experiences and seek ways to improve PA participation. METHODS: Semi-structured intervie... Read More about The attitudes towards, and beliefs about, physical activity in people with osteoarthritis and comorbidity: A qualitative investigation.

Personal Data and Collective Value: Data-Driven Personalisation as Network Effect (2021)
Book Chapter
O’Donovan, N. (2021). Personal Data and Collective Value: Data-Driven Personalisation as Network Effect. In Data-Driven Personalisation in Markets, Politics and Law (74-92). Cambridge University Press (CUP). https://doi.org/10.1017/9781108891325.006

Over recent years, economists, lawyers and regulators have become increasingly interested in the role played by ‘network effects’ in the digital economy: namely, the phenomenon whereby a platform becomes increasingly valuable to its users, the more u... Read More about Personal Data and Collective Value: Data-Driven Personalisation as Network Effect.

Protocol for development of a reporting guideline (TRIPOD-AI) and risk of bias tool (PROBAST-AI) for diagnostic and prognostic prediction model studies based on artificial intelligence. (2021)
Journal Article
(2021). Protocol for development of a reporting guideline (TRIPOD-AI) and risk of bias tool (PROBAST-AI) for diagnostic and prognostic prediction model studies based on artificial intelligence. BMJ Open, e048008 - ?. https://doi.org/10.1136/bmjopen-2020-048008

INTRODUCTION: The Transparent Reporting of a multivariable prediction model of Individual Prognosis Or Diagnosis (TRIPOD) statement and the Prediction model Risk Of Bias ASsessment Tool (PROBAST) were both published to improve the reporting and criti... Read More about Protocol for development of a reporting guideline (TRIPOD-AI) and risk of bias tool (PROBAST-AI) for diagnostic and prognostic prediction model studies based on artificial intelligence..

First Contact Practitioners' (FCPs) and General Practitioners' Perceptions Towards FCPs Delivering Vocational Advice to Patients with Musculoskeletal Conditions: A Qualitative Investigation of the Implementation Potential of the I-SWAP Initiative. (2021)
Journal Article
Saunders, B., Foster, N. E., Hill, J. C., Sowden, G., Evans, N., Bishop, A., …Wynne-Jones, G. (2022). First Contact Practitioners' (FCPs) and General Practitioners' Perceptions Towards FCPs Delivering Vocational Advice to Patients with Musculoskeletal Conditions: A Qualitative Investigation of the Implementation Potential of the I-SWAP Initiative. Journal of Occupational Rehabilitation, 32, 147–155. https://doi.org/10.1007/s10926-021-09992-5

Purpose Musculoskeletal (MSK) pain is a common cause of work absence. The recent SWAP (Study of Work And Pain) randomised controlled trial (RCT) found that a brief vocational advice service for primary care patients with MSK pain led to fewer days' w... Read More about First Contact Practitioners' (FCPs) and General Practitioners' Perceptions Towards FCPs Delivering Vocational Advice to Patients with Musculoskeletal Conditions: A Qualitative Investigation of the Implementation Potential of the I-SWAP Initiative..

The influence of exocyclic lone pairs on the bonding and geometry of type A mesoionic rings (2021)
Journal Article
(2021). The influence of exocyclic lone pairs on the bonding and geometry of type A mesoionic rings. Structural Chemistry, https://doi.org/10.1007/s11224-021-01798-8

Based on structures determined by X-ray crystallography, ab initio MP2 calculations on type A mesoionic rings give geometries in good agreement with observed values. A study of four mesoionic ring systems, each with exocyclic oxygen, nitrogen or carb... Read More about The influence of exocyclic lone pairs on the bonding and geometry of type A mesoionic rings.

Combining multi-omics and drug perturbation profiles to identify muscle-specific treatments for spinal muscular atrophy (2021)
Journal Article
Bowerman. (2021). Combining multi-omics and drug perturbation profiles to identify muscle-specific treatments for spinal muscular atrophy. JCI insight, 1-24. https://doi.org/10.1172/jci.insight.149446

Spinal muscular atrophy (SMA) is a neuromuscular disorder caused by loss of survival motor neuron (SMN) protein. While SMN restoration therapies are beneficial, they are not a cure. We aimed to identify novel treatments to alleviate muscle pathology... Read More about Combining multi-omics and drug perturbation profiles to identify muscle-specific treatments for spinal muscular atrophy.

A new method of contrast enhancement of musculoskeletal ultrasound imaging based on fuzzy inference technique (2021)
Journal Article
Jabbar, S. I., Aladi, A. Q., Day, C., & Chadwick, E. (2021). A new method of contrast enhancement of musculoskeletal ultrasound imaging based on fuzzy inference technique. Biomedical Physics & Engineering Express, 7(5), 055003. https://doi.org/10.1088/2057-1976/ac0dce

Improving the clarity and visual quality of Musculoskeletal Ultrasound Images (MUI) can help clinicians to detect diseases more easily and accurately. In this work, we described how to enhance the contrast of MUI locally based on a fuzzy inference sy... Read More about A new method of contrast enhancement of musculoskeletal ultrasound imaging based on fuzzy inference technique.

Development of 2-Morpholino-N-hydroxybenzamides as anti-proliferative PC-PLC inhibitors (2021)
Journal Article
Rees, S. W., Leung, E., Reynisson, J., Barker, D., & Pilkington, L. I. (2021). Development of 2-Morpholino-N-hydroxybenzamides as anti-proliferative PC-PLC inhibitors. Bioorganic Chemistry, 114, 105152. https://doi.org/10.1016/j.bioorg.2021.105152

Phosphatidylcholine-specific phospholipase C (PC-PLC) is a key enzyme involved in the metabolism of the mammalian phospholipid phosphatidylcholine into secondary messengers diacylglycerol (DAG) and phosphocholine. DAG and phosphocholine have been ide... Read More about Development of 2-Morpholino-N-hydroxybenzamides as anti-proliferative PC-PLC inhibitors.

Dust Production around Carbon-Rich Stars: The Role of Metallicity (2021)
Journal Article
Nanni, A., Cristallo, S., van Loon, J., & Groenewegen, M. (in press). Dust Production around Carbon-Rich Stars: The Role of Metallicity. Universe, 7(7), 233. https://doi.org/10.3390/universe7070233

Background: Most of the stars in the Universe will end their evolution by losing their envelope during the thermally pulsing asymptotic giant branch (TP-AGB) phase, enriching the interstellar medium of galaxies with heavy elements, partially condense... Read More about Dust Production around Carbon-Rich Stars: The Role of Metallicity.

Excess years of life lost to COVID-19 and other causes of death by sex, neighbourhood deprivation and region in England & Wales during 2020 (2021)
Journal Article
Mamas. (2021). Excess years of life lost to COVID-19 and other causes of death by sex, neighbourhood deprivation and region in England & Wales during 2020

Background Deaths in the first year of the COVID-19 pandemic in England & Wales have been shown to be unevenly distributed socioeconomically and geographically. However, the full scale of inequalities may have been underestimated as most measures of... Read More about Excess years of life lost to COVID-19 and other causes of death by sex, neighbourhood deprivation and region in England & Wales during 2020.

Propranolol Reduces Risk of Knee or Hip Replacement Due to Osteoarthritis: a Propensity Score Matched Cohort Study-using Data From the Clinical Practice Research Datalink. (2021)
Journal Article
Mamas, M., & Mallen, C. (2021). Propranolol Reduces Risk of Knee or Hip Replacement Due to Osteoarthritis: a Propensity Score Matched Cohort Study-using Data From the Clinical Practice Research Datalink. Research Square, https://doi.org/10.21203/rs.3.rs-670522/v1

Objectives: To examine the association between ß -blocker prescription and knee or hip total joint replacement (TJR) in a UK primary-care population with incident knee or hip osteoarthritis (OA). Methods: Cohort study using data from the Clinical P... Read More about Propranolol Reduces Risk of Knee or Hip Replacement Due to Osteoarthritis: a Propensity Score Matched Cohort Study-using Data From the Clinical Practice Research Datalink..

The sibling familiarity effect: Is within‐person facial variability shared across siblings? (2021)
Journal Article
Strathie, A., Hughes‐White, N., & Laurence, S. (2022). The sibling familiarity effect: Is within‐person facial variability shared across siblings?. British Journal of Psychology, 113(1), 327-345. https://doi.org/10.1111/bjop.12517

Humans are experts at familiar face recognition, but poor at unfamiliar face recognition. Familiarity is created when a face is encountered across varied conditions, but the way in which a person’s appearance varies is identity-specific, so familiari... Read More about The sibling familiarity effect: Is within‐person facial variability shared across siblings?.