All Outputs (71)

P082 Nephrolithiasis associated with uricosuric therapies for the treatment of gout: a systematic review (2024)
Presentation / Conference

Background/Aims Uric acid nephrolithiasis is a recognised side-effect of uricosuric therapies and a contraindication to their use. The objective of this systematic review was to assess the incidence and risk of nephrolithiasis in people with gout rec... Read More about P082 Nephrolithiasis associated with uricosuric therapies for the treatment of gout: a systematic review.

International variations in serum PTH and calcium levels and their mortality associations in peritoneal dialysis patients: Results from PDOPPS (2024)
Journal Article

Background: Mineral bone disorder (MBD) in chronic kidney disease (CKD) is associated with high symptom burden, fractures, vascular calcification, cardiovascular disease and increased morbidity and mortality. CKD-MBD studies have been limited in peri... Read More about International variations in serum PTH and calcium levels and their mortality associations in peritoneal dialysis patients: Results from PDOPPS.

Adverse pregnancy outcomes in pregnant women with chronic kidney disease: A systematic review and meta‐analysis (2024)
Journal Article

Background: Chronic kidney disease (CKD) is associated with an increased risk of adverse pregnancy outcomes, but the risk at different stages of CKD (defined by estimated glomerular filtration rate, eGFR) compared with women without CKD has not been... Read More about Adverse pregnancy outcomes in pregnant women with chronic kidney disease: A systematic review and meta‐analysis.

Centre variation in home dialysis uptake: A survey of kidney centre practice in relation to home dialysis organisation and delivery in England (2024)
Journal Article

Background: Disparities in home dialysis uptake across England suggest inequity and unexplained variation in access. We surveyed staff at all English kidney centres to identify patterns in service organisation/delivery and explore correlations with h... Read More about Centre variation in home dialysis uptake: A survey of kidney centre practice in relation to home dialysis organisation and delivery in England.

Gastric Acid Suppression Therapy and its Association with Peritoneal Dialysis-Associated Peritonitis in the Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS) (2023)
Journal Article

Background: Peritonitis is a major peritoneal dialysis (PD) related complication. We determined whether gastric acid suppression (GAS) (proton pump inhibitor (PPI) or histamine-2 receptor antagonists (H2RA)) use was associated with all-cause and orga... Read More about Gastric Acid Suppression Therapy and its Association with Peritoneal Dialysis-Associated Peritonitis in the Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS).

Estimating the association between systemic Interleukin-6 and mortality in the dialysis population. Re-analysis of the global fluid study, systematic review and meta-analysis (2023)
Journal Article

Background: Systemic inflammation, measured as circulating Interleukin-6 (IL-6) levels, is associated with cardiovascular and all-cause mortality in chronic kidney disease. However, this has not been convincingly demonstrated in a systematic review o... Read More about Estimating the association between systemic Interleukin-6 and mortality in the dialysis population. Re-analysis of the global fluid study, systematic review and meta-analysis.

An update on absolute and relative indications for dialysis treatment modalities (2023)
Journal Article

Background Choosing a dialysis modality is an important decision for people to make as their kidney failure progresses. In doing so, their options should be informed by any absolute or relative indications that may favour one modality over another. M... Read More about An update on absolute and relative indications for dialysis treatment modalities.

Standards of diabetes care and burden of hypoglycaemia in people with diabetes on peritoneal dialysis: Results from a real-world clinical audit (2023)
Journal Article

There is limited data on the standards of diabetes care in people on peritoneal dialysis (PD). Our aim was to assess the standards of diabetes care and the burden of hypoglycaemia in people with diabetes on PD. We performed a retrospective study at t... Read More about Standards of diabetes care and burden of hypoglycaemia in people with diabetes on peritoneal dialysis: Results from a real-world clinical audit.

The Peritoneal Membrane and its Role in Peritoneal Dialysis. (2023)
Journal Article

A healthy and functional peritoneal membrane is key to achieve sufficient ultrafiltration and to restore fluid balance, a major component of high-quality prescription in patients treated with peritoneal dialysis (PD). Variability in membrane function... Read More about The Peritoneal Membrane and its Role in Peritoneal Dialysis..

A systematic review of acute kidney injury in pregnancy and cardio-renal outcomes (2023)
Presentation / Conference

Narrative Review of Glycemic Management in People With Diabetes on Peritoneal Dialysis (2023)
Journal Article

There is an increasing number of people with diabetes on peritoneal dialysis (PD) worldwide. However, there is a lack of guidelines and clinical recommendations for managing glucose control in people with diabetes on PD. The aim of this review is to... Read More about Narrative Review of Glycemic Management in People With Diabetes on Peritoneal Dialysis.

IMPROVE-PD Finder: A Web-Based Platform to Search and Share Peritoneal Dialysis Biobank, Registry, and Clinical Trial Metadata (2023)
Journal Article

Peritoneal dialysis (PD) is a life-sustaining kidney replacement therapy for the increasing number of people with permanent kidney failure across all age groups worldwide. Although PD potentially offers socioeconomic and performance benefits over hem... Read More about IMPROVE-PD Finder: A Web-Based Platform to Search and Share Peritoneal Dialysis Biobank, Registry, and Clinical Trial Metadata.

Management of adults with diabetes on dialysis: Summary of recommendations of the Joint British Diabetes Societies guidelines 2022 (2022)
Journal Article

Diabetes is the commonest cause of end-stage kidney disease in many parts of the world, and many people on dialysis programmes live with diabetes. Such people are vulnerable to complications from their diabetes, and their care may be fragmented due t... Read More about Management of adults with diabetes on dialysis: Summary of recommendations of the Joint British Diabetes Societies guidelines 2022.

Salt and Water Balance (2022)
Book Chapter

Achieving salt and water balance is fundamental to optimizing fluid status, one of the key objectives of peritoneal dialysis (PD) treatment. The relative importance of salt and water management to patient outcomes was historically underestimated by e... Read More about Salt and Water Balance.

Intervening to eliminate the centre-effect variation in home dialysis use: protocol for Inter-CEPt—a sequential mixed-methods study designing an intervention bundle (2022)
Journal Article

INTRODUCTION: Use of home dialysis by centres in the UK varies considerably and is decreasing despite attempts to encourage greater use. Knowing what drives this unwarranted variation requires in-depth understanding of centre cultural and organisatio... Read More about Intervening to eliminate the centre-effect variation in home dialysis use: protocol for Inter-CEPt—a sequential mixed-methods study designing an intervention bundle.

Variation in Peritoneal Dialysis Time on Therapy by Country: Results from the Peritoneal Dialysis Outcomes and Practice Patterns Study. (2022)
Journal Article

Background and objectives Quantifying contemporary peritoneal dialysis time on therapy is important for patients and providers. We describe time on peritoneal dialysis in the context of outcomes of hemodialysis transfer, death, and kidney transplanta... Read More about Variation in Peritoneal Dialysis Time on Therapy by Country: Results from the Peritoneal Dialysis Outcomes and Practice Patterns Study..

Risk factors associated with COVID-19 severity among patients on maintenance haemodialysis: a retrospective multicentre cross-sectional study in the UK (2022)
Journal Article

Objectives To assess the applicability of risk factors for severe COVID-19 defined in the general population for patients on haemodialysis. Setting A retrospective cross-sectional study performed across thirty four haemodialysis units in midlands... Read More about Risk factors associated with COVID-19 severity among patients on maintenance haemodialysis: a retrospective multicentre cross-sectional study in the UK.

Mortality Trends After Transfer From Peritoneal Dialysis to Hemodialysis (2022)
Journal Article

Introduction Transition to hemodialysis (HD) is a common outcome in peritoneal dialysis (PD), but the associated mortality risk is poorly understood. This study sought to identify rates of and risk factors for mortality after transitioning from PD t... Read More about Mortality Trends After Transfer From Peritoneal Dialysis to Hemodialysis.

Widening access to the specialised foundation programme (2022)
Journal Article

The specialised foundation programme, previously known as the academic foundation programme, is an alternate foundation training pathway for doctors that are interested in research, medical education and leadership. The programme is highly competiti... Read More about Widening access to the specialised foundation programme.

AQP1 Promoter Variant, Water Transport, and Outcomes in Peritoneal Dialysis. (2021)
Journal Article

BACKGROUND: Variability in ultrafiltration influences prescriptions and outcomes in patients with kidney failure who are treated with peritoneal dialysis. Variants in AQP1, the gene that encodes the archetypal water channel aquaporin-1, may contribut... Read More about AQP1 Promoter Variant, Water Transport, and Outcomes in Peritoneal Dialysis..