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Narrative Review of Glycemic Management in People With Diabetes on Peritoneal Dialysis

Wijewickrama, Piyumi; Williams, Jennifer; Bain, Steve; Dasgupta, Indranil; Chowdhury, Tahseen A.; Wahba, Mona; Frankel, Andrew H.; Lambie, Mark; Karalliedde, Janaka


Piyumi Wijewickrama

Jennifer Williams

Steve Bain

Indranil Dasgupta

Tahseen A. Chowdhury

Mona Wahba

Andrew H. Frankel

Janaka Karalliedde


There is an increasing number of people with diabetes on peritoneal dialysis (PD) worldwide. However, there is a lack of guidelines and clinical recommendations for managing glucose control in people with diabetes on PD. The aim of this review is to provide a summary of the relevant literature and highlight key clinical considerations with practical aspects in the management of diabetes in people undergoing PD. A formal systematic review was not conducted because of the lack of sufficient and suitable clinical studies. A literature search was performed using PubMed, MEDLINE, Central, Google Scholar and, from 1980 through February 2022. The search was limited to publications in English. This narrative review and related guidance have been developed jointly by diabetologists and nephrologists, who reviewed all available current global evidence regarding the management of diabetes in people on PD.We focus on the importance of individualized care for people with diabetes on PD, the burden of hypoglycemia, glycemic variability in the context of PD and treatment choices for optimizing glucose control. In this review, we have summarized the clinical considerations to guide and inform clinicians providing care for people with diabetes on PD.

Journal Article Type Article
Acceptance Date Jan 30, 2023
Online Publication Date Feb 9, 2023
Publication Date 2023-04
Deposit Date Aug 22, 2023
Print ISSN 2468-0249
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 8
Issue 4
Pages 700-714
Keywords diabetes; kidney failure; peritoneal dialysis