Antibiotics for relapses of protracted bacterial bronchitis
(2024)
Journal Article
All Outputs (17)
COVID‐19 infection and nocardiosis causing the death of an adolescent with cystic fibrosis (2022)
Journal Article
Letter
Interventions for treating distal intestinal obstruction syndrome (DIOS) in cystic fibrosis (2021)
Journal Article
BACKGROUND: Cystic fibrosis is the most common life-limiting autosomal recessive genetic disorder in white populations. Distal intestinal obstruction syndrome (DIOS) is an important morbidity in cystic fibrosis. It is the result of the accumulation o... Read More about Interventions for treating distal intestinal obstruction syndrome (DIOS) in cystic fibrosis.
Interventions for preventing distal intestinal obstruction syndrome (DIOS) in cystic fibrosis (2021)
Journal Article
Background Cystic fibrosis (CF) is the most common, life‐limiting, genetically inherited disease. It affects multiple organs, particularly the respiratory system. However, gastrointestinal problems such as constipation and distal intestinal obstruct... Read More about Interventions for preventing distal intestinal obstruction syndrome (DIOS) in cystic fibrosis.
Chapter 17: Respiratory Disorders (2021)
Book Chapter
The ERS approach to e-cigarettes is entirely rational (2020)
Journal Article
'No abstract'
Duration of initial antibiotic course is associated with recurrent relapse in protracted bacterial bronchitis (2019)
Presentation / Conference
Background: Protracted Bacterial Bronchitis (PBB) is a leading cause of chronic wet cough in children. Antibiotic response is a diagnostic criterion but there is little evidence to inform duration of treatment. Relapse is common and those who relapse... Read More about Duration of initial antibiotic course is associated with recurrent relapse in protracted bacterial bronchitis.
Unwarranted use of intravenous aminoglycosides at UK paediatric cystic fibrosis centres (2019)
Journal Article
Highlights IV aminoglycosides are frequently used to treat infective exacerbations in CF due to efficacy against PA. The side effects of aminoglycosides include nephrotoxicity, ototoxicity and vestibulotoxicity. More than one third of UK CF... Read More about Unwarranted use of intravenous aminoglycosides at UK paediatric cystic fibrosis centres.
Interventions for preventing distal intestinal obstruction syndrome (DIOS) in cystic fibrosis. (2018)
Journal Article
BACKGROUND: Cystic fibrosis (CF) is the most common, life-limiting, genetically inherited disease. It affects multiple organs, particularly the respiratory system. However, gastrointestinal problems such as constipation and distal intestinal obstruct... Read More about Interventions for preventing distal intestinal obstruction syndrome (DIOS) in cystic fibrosis..
Comparing the management of constipation and distal intestinal obstruction syndrome between paediatricians and adult physicians. (2017)
Journal Article
No abstract
Modeling Nutritional Outcomes for Infants Diagnosed With Cystic Fibrosis by Newborn Screening (Meeting Abstract) (2016)
Journal Article
Meeting abstract published in supplement of the Thorax journal, December 2016.
Combined influence of gene-specific cord blood methylation and maternal smoking habit on birth weight (2013)
Journal Article
Aim: Evidence suggests that folic acid intake affects birth weight and that these effects may be mediated via the fetal epigenome. Our previous array data indicate that methylation in human cord blood at gene-specific CpGs is associated with birth we... Read More about Combined influence of gene-specific cord blood methylation and maternal smoking habit on birth weight.
Antiepileptic drugs and the fetal epigenome (2012)
Journal Article
Antiepileptic drugs (AEDs) can lower maternal folate and increase maternal homocysteine levels, which are known to affect the methyl cycle and hence DNA methylation levels. The influence of in utero exposure to AEDs on fetal DNA methylation was inves... Read More about Antiepileptic drugs and the fetal epigenome.
Asthma severity and atopy: how clear is the relationship? (2006)
Journal Article
BACKGROUND: The relationship between asthma severity and atopy is complex. Many studies have failed to show significant relationships between clinical severity or lung function and markers of atopic sensitisation. AIM: To determine whether increasing... Read More about Asthma severity and atopy: how clear is the relationship?.
Effects of glutathione S-transferase M1, T1 and P1 on lung function in asthmatic families. (2005)
Journal Article
RATIONALE: Previous data have suggested that glutathione-S-transferase (GST) genotypes are important in determining the rate of lung function growth in childhood. This effect was most marked in Caucasian children with asthma. OBJECTIVES: We investiga... Read More about Effects of glutathione S-transferase M1, T1 and P1 on lung function in asthmatic families..
Maternal glutathione S-transferase GSTP1 genotype is a specific predictor of phenotype in children with asthma. (2005)
Journal Article
Maternal factors are known to influence the heritability and expression of asthma and atopy. We report the association of maternal, paternal and proband GSTP1 genotype with lung function in 145 Caucasian children with asthma. GSTP1 Val105/Val105 and... Read More about Maternal glutathione S-transferase GSTP1 genotype is a specific predictor of phenotype in children with asthma..