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All Outputs (5132)

The prescription and monitoring of conventional synthetic disease-modifying anti-rheumatic drugs: British Society for Rheumatology guideline scope (2024)
Journal Article
Mercer, L., Abhishek, A., Kavirayani, A., Ahmed, A., Davidson, A., Foulkes, A., …Galloway, J. (in press). The prescription and monitoring of conventional synthetic disease-modifying anti-rheumatic drugs: British Society for Rheumatology guideline scope. Rheumatology Advances in Practice, 8(3), Article rkae077. https://doi.org/10.1093/rap/rkae077

Lay Summary: What does this mean for patients? A revised guideline, produced by the British Society for Rheumatology (BSR), will provide up-to-date information about the safe prescribing and monitoring of the effects of non-biologic (or conventional... Read More about The prescription and monitoring of conventional synthetic disease-modifying anti-rheumatic drugs: British Society for Rheumatology guideline scope.

Google Internet searches related to inflammatory arthritis: An observational study using Google Trends data (2024)
Journal Article
Akthar, M., Mason, K. J., & Scott, I. C. (2024). Google Internet searches related to inflammatory arthritis: An observational study using Google Trends data. Musculoskeletal Care, 22(3), Article e1916. https://doi.org/10.1002/msc.1916

Objective: The Internet has transformed how patients access health information. We examined Google search engine data to understand which aspects of health are most often searched for in combination with inflammatory arthritis (IA). Methods: Using Go... Read More about Google Internet searches related to inflammatory arthritis: An observational study using Google Trends data.

Inter-school variations in the standard of examiners’ graduation-level OSCE judgements (2024)
Journal Article
Yeates, P., Maluf, A., McCray, G., Kinston, R., Cope, N., Cullen, K., …McKinley, R. (2024). Inter-school variations in the standard of examiners’ graduation-level OSCE judgements. Medical Teacher, https://doi.org/10.1080/0142159X.2024.2372087

Introduction Ensuring equivalence in high-stakes performance exams is important for patient safety and candidate fairness. We compared inter-school examiner differences within a shared OSCE and resulting impact on students’ pass/fail categorisation.... Read More about Inter-school variations in the standard of examiners’ graduation-level OSCE judgements.

Using Twitter (X) to mobilise knowledge for First Contact Physiotherapists: A qualitative study (Preprint) (2024)
Journal Article
Campbell, L., Quicke, J., Stevenson, K., Paskins, Z., Dziedzic, K., & Swaithes, L. (2024). Using Twitter (X) to mobilise knowledge for First Contact Physiotherapists: A qualitative study (Preprint). Journal of Medical Internet Research, 26, Article e55680. https://doi.org/10.2196/55680

Background: Twitter (now X) is a virtual social network commonly used by healthcare professionals. Little is known about whether it helps healthcare professionals to share, mobilise and co-create knowledge, or reduce the time between research know... Read More about Using Twitter (X) to mobilise knowledge for First Contact Physiotherapists: A qualitative study (Preprint).

The Relationship Between Obesity and Patient-Reported Outcome Measures in People with Polymyalgia Rheumatica (2024)
Journal Article
Scott, I. C., Bajpai, R., Hider, S. L., Helliwell, T., Mallen, C. D., & Muller, S. (in press). The Relationship Between Obesity and Patient-Reported Outcome Measures in People with Polymyalgia Rheumatica. Rheumatology Advances in Practice, 8(3), Article rkae081. https://doi.org/10.1093/rap/rkae081

Objective To examine the association between obesity and patient-reported outcomes measures (PROMs) in a primary care-based cohort of people with polymyalgia rheumatica (PMR). Methods The PMR Cohort Study recruited people with incident PMR from... Read More about The Relationship Between Obesity and Patient-Reported Outcome Measures in People with Polymyalgia Rheumatica.

Musculoskeletal Health and Work: Development and Internal–External Cross-Validation of a Model to Predict Risk of Work Absence and Presenteeism in People Seeking Primary Healthcare (2024)
Journal Article
Archer, L., Peat, G., Snell, K. I. E., Hill, J. C., Dunn, K. M., Foster, N. E., …Wynne-Jones, G. (2024). Musculoskeletal Health and Work: Development and Internal–External Cross-Validation of a Model to Predict Risk of Work Absence and Presenteeism in People Seeking Primary Healthcare. Journal of Occupational Rehabilitation, https://doi.org/10.1007/s10926-024-10223-w

Purpose To develop and validate prediction models for the risk of future work absence and level of presenteeism, in adults seeking primary healthcare with musculoskeletal disorders (MSD). Methods Six studies from the West-Midlands/Northwest regi... Read More about Musculoskeletal Health and Work: Development and Internal–External Cross-Validation of a Model to Predict Risk of Work Absence and Presenteeism in People Seeking Primary Healthcare.

Automating incidence and prevalence analysis in open cohorts (2024)
Journal Article
Cockburn, N., Hammond, B., Gani, I., Cusworth, S., Acharya, A., Gokhale, K., …Chandan, J. S. (in press). Automating incidence and prevalence analysis in open cohorts. BMC medical research methodology, 24, Article 144. https://doi.org/10.1186/s12874-024-02266-7

Motivation: Data is increasingly used for improvement and research in public health, especially administrative data such as that collected in electronic health records. Patients enter and exit these typically open-cohort datasets non-uniformly; this... Read More about Automating incidence and prevalence analysis in open cohorts.

Contextualising and challenging under-representation in research in light of Cultural Trauma: a qualitative focus group and interview study (2024)
Journal Article
Fryer, K., Hutt, I., Aminu, H., Linton, E., White, J., Reynolds, J., & Mitchell, C. (in press). Contextualising and challenging under-representation in research in light of Cultural Trauma: a qualitative focus group and interview study. Research Involvement and Engagement, 10(1), Article 69. https://doi.org/10.1186/s40900-024-00600-3

Background: Although underserved populations— including those from ethnic minority communities and those living in poverty—have worse health and poorer healthcare experiences, most primary care research does not fairly reflect these groups. Patient a... Read More about Contextualising and challenging under-representation in research in light of Cultural Trauma: a qualitative focus group and interview study.

O05 Risk of keratinocyte carcinomas in patients with psoriasis treated with biologic therapy: analysis from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR), on behalf of the BADBIR Study Group (2024)
Presentation / Conference
Esse, S., Alabas, O., Mason, K., Ryan, S., Reynolds, N., Smith, C., …Warren, R. (2024, July). O05 Risk of keratinocyte carcinomas in patients with psoriasis treated with biologic therapy: analysis from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR), on behalf of the BADBIR Study Group. Presented at 104th Annual Meeting of the British Association of Dermatologists, Manchester

Previous literature suggests an association between the use of biologics and the development of keratinocyte carcinoma in psoriasis. Our aim was to evaluate the risks of developing basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (SCC... Read More about O05 Risk of keratinocyte carcinomas in patients with psoriasis treated with biologic therapy: analysis from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR), on behalf of the BADBIR Study Group.

P072 Risk of incident cancer, excluding keratinocyte carcinoma, in patients with psoriasis treated with biologic therapy: a prospective cohort study from the British Association of Dermatologists Biologic and Immunomodulators Register (BADBIR), on behalf of the BADBIR Study Group (2024)
Presentation / Conference
Esse, S., Alabas, O., Mason, K., Ryan, S., Reynolds, N., Smith, C., …Warren, R. (2024, July). P072 Risk of incident cancer, excluding keratinocyte carcinoma, in patients with psoriasis treated with biologic therapy: a prospective cohort study from the British Association of Dermatologists Biologic and Immunomodulators Register (BADBIR), on behalf of the BADBIR Study Group. Poster presented at 104th Annual Meeting of the British Association of Dermatologists, Manchester

There are long-standing concerns that the use of biologic therapies to treat patients with psoriasis could confer an increased risk of developing cancer due to their immunomodulatory effects. We aimed to assess the risk of any incident cancer (exclud... Read More about P072 Risk of incident cancer, excluding keratinocyte carcinoma, in patients with psoriasis treated with biologic therapy: a prospective cohort study from the British Association of Dermatologists Biologic and Immunomodulators Register (BADBIR), on behalf of the BADBIR Study Group.

Understanding the preferences of young adults with type 2 diabetes mellitus with regard to diabetes self-management education: a qualitative study (2024)
Journal Article
Sim, R. R. J., Soon, W., Smith, H. E., Griva, K., & Wong, S. K. W. (2024). Understanding the preferences of young adults with type 2 diabetes mellitus with regard to diabetes self-management education: a qualitative study. BMJ Open, 14(7), Article e086133. https://doi.org/10.1136/bmjopen-2024-086133

Aim: Young-onset type 2 diabetes (YOD) is associated with poorer clinical outcomes. To support the development of more effective diabetes self-management education (DSME) programmes, this study aimed to understand the preferences of young adults with... Read More about Understanding the preferences of young adults with type 2 diabetes mellitus with regard to diabetes self-management education: a qualitative study.

Optimising physiotherapy treatment for people with lateral elbow tendinopathy: development and pilot/feasibility testing of an evidence-based treatment approach (2024)
Thesis
Bateman, M. (2024). Optimising physiotherapy treatment for people with lateral elbow tendinopathy: development and pilot/feasibility testing of an evidence-based treatment approach. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/853496

Background: There are a wide range of physiotherapy treatment options for people with lateral elbow tendinopathy (LET), however previous studies have reported inconsistent approaches to treatment and a lack of evidence demonstrating clinical effectiv... Read More about Optimising physiotherapy treatment for people with lateral elbow tendinopathy: development and pilot/feasibility testing of an evidence-based treatment approach.

How do males of South Asian origin with long-term physical conditions understand, experience and seek help for emotional distress? (2024)
Thesis
Awan, H. (2024). How do males of South Asian origin with long-term physical conditions understand, experience and seek help for emotional distress?. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/849807

People with physical-mental comorbidity have a poorer quality of life, worse clinical outcomes and increased mortality than those with physical conditions alone. Those from some ethnic groups may be less likely to recognise and seek help for symptoms... Read More about How do males of South Asian origin with long-term physical conditions understand, experience and seek help for emotional distress?.

Investigating the therapeutic potential of repurposed drugs that target central nervous system and peripheral pathologies in cellular and animal models of spinal muscular atrophy (2024)
Thesis
Çetin, Ö. (2024). Investigating the therapeutic potential of repurposed drugs that target central nervous system and peripheral pathologies in cellular and animal models of spinal muscular atrophy. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/853197

Spinal muscular atrophy (SMA) is a neuromuscular disorder caused by the loss-of-function of the survival motor neuron (SMN) gene resulting in muscle atrophy and weakness. There are currently 3 gene-based therapies (Spinraza®, Zolgensma® and Evrysdi®)... Read More about Investigating the therapeutic potential of repurposed drugs that target central nervous system and peripheral pathologies in cellular and animal models of spinal muscular atrophy.

Towards an ethically informed framework for managing patients with medically unexplained symptoms: developing boundary principles (2024)
Thesis
Fernando, B. L. (2024). Towards an ethically informed framework for managing patients with medically unexplained symptoms: developing boundary principles. (Thesis). Keele University. Retrieved from https://keele-repository.worktribe.com/output/855660

Introduction Patients with medically unexplained symptoms (MUS), i.e., physical complaints not fully explained by somatic/psychiatric pathology, are well-documented as a significant problem in primary care. Yet, the issues these patients and their... Read More about Towards an ethically informed framework for managing patients with medically unexplained symptoms: developing boundary principles.

Nutrition for Older Adults With Osteoarthritis: Empowering People in Sub-Saharan Africa With Information for Self-Management in Line With Core Guideline Recommendations (2024)
Journal Article
Owoyemi, T. L., Babatunde, O., Adetunji, O., Alonge, I., Ogunbanjo, A., & Adebajo, A. O. (2024). Nutrition for Older Adults With Osteoarthritis: Empowering People in Sub-Saharan Africa With Information for Self-Management in Line With Core Guideline Recommendations. Current Developments in Nutrition, 8(S2), Article 102214. https://doi.org/10.1016/j.cdnut.2024.102214

Objectives: This study was part of a project aimed to provide consistent, culturally acceptable, and accessible information on OA. Specifically, we sought to support healthcare professionals with evidence-based care and empower older adults to self-m... Read More about Nutrition for Older Adults With Osteoarthritis: Empowering People in Sub-Saharan Africa With Information for Self-Management in Line With Core Guideline Recommendations.

PS04 Suicide risk in patients with psoriasis: results from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR) (2024)
Journal Article
Williams, K., Lada, G., Reynolds, N., Mcelhone, K., Evans, I., Walton, S., …Kleyn, C. E. (2024). PS04 Suicide risk in patients with psoriasis: results from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR). British Journal of Dermatology, 191(Supplement_1), i177-i177. https://doi.org/10.1093/bjd/ljae090.375

Psoriasis is associated with poor mental health, high prevalence of depression and reduced quality of life. However, suicide risk in this group is unclear. Previous meta-analyses have provided conflicting results regarding risk of suicidality outcome... Read More about PS04 Suicide risk in patients with psoriasis: results from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR).

Healthcare practitioners' views of self‐harm management practices in older adults in Ireland: A qualitative study (2024)
Journal Article
Troya, M. I., Lonergan, C., Cassidy, E., Griffin, E., Lovejoy, S. A., Mughal, F., …Arensman, E. (2024). Healthcare practitioners' views of self‐harm management practices in older adults in Ireland: A qualitative study. International Journal of Geriatric Psychiatry, 39(7), Article e6116. https://doi.org/10.1002/gps.6116

Objectives To explore healthcare practitioners' views on management practices of self-harm in older adults. Methods Semi-structured interviews were conducted with healthcare practitioners, including consultant psychiatrists, general practitioner... Read More about Healthcare practitioners' views of self‐harm management practices in older adults in Ireland: A qualitative study.

Performance of CHA 2 DS 2 -VASc and HAS-BLED in predicting stroke and bleeding in atrial fibrillation and cancer (2024)
Journal Article
Ajabnoor, A. M., Zghebi, S. S., Parisi, R., Ashcroft, D. M., Faivre-Finn, C., Mamas, M. A., & Kontopantelis, E. (2024). Performance of CHA 2 DS 2 -VASc and HAS-BLED in predicting stroke and bleeding in atrial fibrillation and cancer. European Heart Journal Open, 4(4), Article oeae053. https://doi.org/10.1093/ehjopen/oeae053

Aims: To compare the predictive performance of CHA2DS2-VASc and HAS-BLED scores in atrial fibrillation (AF) patients with and without cancer. Methods and results: Using data from the Clinical Practice Research Datalink in England, we performed a retr... Read More about Performance of CHA 2 DS 2 -VASc and HAS-BLED in predicting stroke and bleeding in atrial fibrillation and cancer.