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REPRODUCIBILITY OF LUNG CLEARANCE INDEX (LCI) IN CLINICALLY STABLE ADULTS WITH MILD CYSTIC FIBROSIS (CF)
Presentation / Conference
Gilchrist. REPRODUCIBILITY OF LUNG CLEARANCE INDEX (LCI) IN CLINICALLY STABLE ADULTS WITH MILD CYSTIC FIBROSIS (CF). Presented at British Thoracic Society Winter Meeting 2016

Background In order for lung clearance index (LCI) to be a clinically useful measurement, a better understanding is required of short-term variability. LCI-SEARCH is a longitudinal study in children and adults with CF, with LCI measured at each clini... Read More about REPRODUCIBILITY OF LUNG CLEARANCE INDEX (LCI) IN CLINICALLY STABLE ADULTS WITH MILD CYSTIC FIBROSIS (CF).

Rapid and portable MBW measurements for clinical application of LCI in routine clinics
Presentation / Conference
Gilchrist. Rapid and portable MBW measurements for clinical application of LCI in routine clinics. Presented at ERS Lung Science Conference 2016

Background: Assessment of lung clearance index (LCI) is typically a prolonged process (>20mins), performed in physiology labs. This has hindered routine clinical application and restricted repeat assessments to annual reviews. We have developed a por... Read More about Rapid and portable MBW measurements for clinical application of LCI in routine clinics.

The potential of closed circuit lung clearance index (LCI) to provide longitudinal clinical utility in cystic fibrosis (CF)
Presentation / Conference
Gilchrist. The potential of closed circuit lung clearance index (LCI) to provide longitudinal clinical utility in cystic fibrosis (CF). Presented at https://erj.ersjournals.com/content/54/suppl_63/PA332

Background: Closed circuit washin offers a quicker test with the advantages of an exogenous tracer to measure FRC and LCI. We measured LCI in CF paediatric and adult outpatient clinics to assess repeatability of LCI and track changes over time, and i... Read More about The potential of closed circuit lung clearance index (LCI) to provide longitudinal clinical utility in cystic fibrosis (CF).

The treatment of poverty in Nantwich and Crewe 1730-1914
Thesis
Edwards, F. The treatment of poverty in Nantwich and Crewe 1730-1914. https://keele-repository.worktribe.com/output/422668

This thesis examines the various ways in which poverty was treated in Crewe and Nantwich from the operation of the old Poor Law to 1914 when a complex combination of private and public effort existed in an attempt to ease the plight of the Poor. The... Read More about The treatment of poverty in Nantwich and Crewe 1730-1914.

OB Associations
Presentation / Conference
Jeffries, & Wright. OB Associations. Presented at Protostars and Planets VII

OB associations are low-density groups of young stars that are dispersing from their birth environment into the Galactic field. They are important for understanding the star formation process, early stellar evolution, the properties and distribution... Read More about OB Associations.

Feasibility of identifying prognostic factors for total joint arthroplasty in electronic primary health care records
Thesis
Turner, M. A. Feasibility of identifying prognostic factors for total joint arthroplasty in electronic primary health care records. https://keele-repository.worktribe.com/output/422986

The ability to identify osteoarthritis (OA) patients at high risk of progressing to joint arthroplasty surgery could enable earlier, targeted nonsurgical management in primary care. The ability to do so using only information routinely recorded withi... Read More about Feasibility of identifying prognostic factors for total joint arthroplasty in electronic primary health care records.

Role of Cyclin D1 polymorphisms and protein over-expression in clinical outcomes of colorectal cancer
Thesis
Sivakumar, R. Role of Cyclin D1 polymorphisms and protein over-expression in clinical outcomes of colorectal cancer. https://keele-repository.worktribe.com/output/422989

Cyclin D1 is a key regulatory protein in the progression of G1-S phase of the cell cycle. Activated Cyclin D1 in turn activates S phase proteins and thereby leading to cell proliferation. Over expression of Cyclin D1 leads S phase cell cycle progress... Read More about Role of Cyclin D1 polymorphisms and protein over-expression in clinical outcomes of colorectal cancer.

P060 Living with rheumatoid arthritis during the coronavirus pandemic: a longitudinal interview study
Presentation / Conference Contribution
Campbell, P., Paskins, Z., Hider, S., Hassell, A., Crawford-Manning, F., Rule, K., Brooks, M., & Ryan, S. P060 Living with rheumatoid arthritis during the coronavirus pandemic: a longitudinal interview study. Poster presented at British Society for Rheumatology Annual Conference

Background/Aims The COVID-19 pandemic placed patients with rheumatoid arthritis (RA) at increased risk of poor outcomes as a result of their condition, compounded by use of immunosuppressant medication, and higher prevalence of comorbidities. As a co... Read More about P060 Living with rheumatoid arthritis during the coronavirus pandemic: a longitudinal interview study.

SEX DIFFERENCES IN HIGH-RISK BUT INDICATED CORONARY INTERVENTIONS. NATIONAL REPORT FROM THE BRITISH CARDIOVASCULAR INTERVENTION SOCIETY REGISTRY
Presentation / Conference
Mamas, & Rashid. SEX DIFFERENCES IN HIGH-RISK BUT INDICATED CORONARY INTERVENTIONS. NATIONAL REPORT FROM THE BRITISH CARDIOVASCULAR INTERVENTION SOCIETY REGISTRY. Presented at ACC.22

Background: Complex and high-risk but indicated percutaneous coronary intervention (CHiP) is increasingly common in contemporary PCI practice. Data on sex differences in the type of CHiP procedures undertaken or their associated clinical outcomes are... Read More about SEX DIFFERENCES IN HIGH-RISK BUT INDICATED CORONARY INTERVENTIONS. NATIONAL REPORT FROM THE BRITISH CARDIOVASCULAR INTERVENTION SOCIETY REGISTRY.

Vitamin D supplementation for improving bone density in vitamin D-deficient children: a systematic review and individual participant data meta-analysis of randomized controlled trials
Presentation / Conference Contribution
Wu, F., El-Hajj Fuleihan, G., Cai, G., Lamberg-Allardt, C., Viljakainen, H. T., Rahme, M., Grønborg, I. M., Andersen, R., Khadilkar, A., Zulf Mughal, M., Mølgaard, C., Larnkjær, A., Zhu, K., Riley, R. D., & Winzenberg, T. Vitamin D supplementation for improving bone density in vitamin D-deficient children: a systematic review and individual participant data meta-analysis of randomized controlled trials. Presented at Journal of Bone and Mineral Research

'Meeting Abstract'

Modelling the population distribution of patient-reported outcomes using electronic health records: a UK study
Presentation / Conference
Wilkie, Yu, & Jordan. Modelling the population distribution of patient-reported outcomes using electronic health records: a UK study. Presented at IEA WORLD CONGRESS OF EPIDEMIOLOGY 2021

Background Patient Reported Outcome Measures (PROM) collected in surveys allow understanding of the health at the population-level. We aimed to test the feasibility of estimating health status as measured by PROMs through ecological prediction models... Read More about Modelling the population distribution of patient-reported outcomes using electronic health records: a UK study.

Juvenile Chondrocytes: Novel Alternatives for Allogeneic Cell Therapy?
Presentation / Conference
Hulme, C., & Wright, K. Juvenile Chondrocytes: Novel Alternatives for Allogeneic Cell Therapy?. Presented at International Cartilage Regeneration and Joint Preservation Society (ICRS) World Congress 2022

Purpose
Development of novel allogeneic chondrocyte therapies are needed to provide a more widespread, cost-effective cartilage treatment option. Here we investigate the potential of juvenile cartilage sources for allogeneic chondrocyte manufactur... Read More about Juvenile Chondrocytes: Novel Alternatives for Allogeneic Cell Therapy?.

The sedimentological characteristics of basal ice and their preservation within the proglacial environment
Thesis
Cutts, S. L. The sedimentological characteristics of basal ice and their preservation within the proglacial environment. (Thesis). https://keele-repository.worktribe.com/output/423747

The identification of distinctive sedimentological characteristics within the basal ice layer (BIL), and their potential preservation within the proglacial environment, is crucial to enhancing our understanding of glaciological conditions beneath ice... Read More about The sedimentological characteristics of basal ice and their preservation within the proglacial environment.

Shared decision-making around analgesia for musculoskeletal pain in primary care consultations
Thesis
Hyde, C. Shared decision-making around analgesia for musculoskeletal pain in primary care consultations. https://keele-repository.worktribe.com/output/423751

Background
Musculoskeletal (MSK) pain is a major health problem worldwide and in UK primary care. Shared decision-making (SDM) is a process advocated by UK policy directives whereby a general practitioner (GP) and patient share information and the... Read More about Shared decision-making around analgesia for musculoskeletal pain in primary care consultations.

Developing a non-invasive method for in vivo monitoring of forearm flexor tendon excursions during rehabilitation following surgical tendon repair
Thesis
Sharma, R. Developing a non-invasive method for in vivo monitoring of forearm flexor tendon excursions during rehabilitation following surgical tendon repair. https://keele-repository.worktribe.com/output/423752

Background: An injury to the wrist and hand can impact different anatomical structures. Any damage or cut to the flexor tendons can leave a devastating impact if not treated well and can therefore compromise our daily physical activities. Surgery and... Read More about Developing a non-invasive method for in vivo monitoring of forearm flexor tendon excursions during rehabilitation following surgical tendon repair.