Tina Dale's Outputs (2)

Human tendon stem/progenitor cell-derived extracellular vesicle production promoted by dynamic culture (2025)
Journal Article
Clerici, M., Camilla Ciardulli, M., Pavel Lamparelli, E., Lovecchio, J., Giordano, E., Dale, T. P., Forsyth, N. R., Maffulli, N., & Della Porta, G. (2025). Human tendon stem/progenitor cell-derived extracellular vesicle production promoted by dynamic culture. Artificial Cells, Nanomedicine, and Biotechnology, 53(1), 1-16. https://doi.org/10.1080/21691401.2025.2475099

Tendon injuries significantly impact quality of life, prompting the exploration of innovative solutions beyond conventional surgery. Extracellular Vesicles (EVs) have emerged as a promising strategy to enhance tendon regeneration. In this study, huma... Read More about Human tendon stem/progenitor cell-derived extracellular vesicle production promoted by dynamic culture.

The Human Mesenchymal Stem Cell Secretome Directs Macrophage Differentiation in an Oxygen-Dependent Manner (2023)
Preprint / Working Paper
Shephard, M. T., Merkhan, M. M., Dale, T. P., & Forsyth, N. R. (2023). The Human Mesenchymal Stem Cell Secretome Directs Macrophage Differentiation in an Oxygen-Dependent Manner

Background
Chronic disease states can share inflammation as an underlying pathology. Macrophages are associated with chronic inflammation; in general, M1 phenotype macrophage activity inhibits cell proliferation and causes tissue damage whilst M2 ma... Read More about The Human Mesenchymal Stem Cell Secretome Directs Macrophage Differentiation in an Oxygen-Dependent Manner.