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Mamas Mamas' Outputs (1085)

Impact of Cardiovascular–Kidney–Metabolic Syndrome Staging on Myocardial Infarction Outcomes: A Retrospective Analysis of 2.7 Million Patients (2025)
Journal Article
Shabtai, R., Gatuz, M. V., Folman, A., Barel, M. S., Abu-Fanne, R., Abramov, D., Mamas, M. A., Roguin, A., & Kobo, O. (in press). Impact of Cardiovascular–Kidney–Metabolic Syndrome Staging on Myocardial Infarction Outcomes: A Retrospective Analysis of 2.7 Million Patients. Diseases, 13(4), 97. https://doi.org/10.3390/diseases13040097

Background: Cardiovascular–kidney–metabolic (CKM) syndrome, recently defined by the American Heart Association, encompasses the interplay between obesity, diabetes, chronic kidney disease, and cardiovascular disease. This study aimed to investigate t... Read More about Impact of Cardiovascular–Kidney–Metabolic Syndrome Staging on Myocardial Infarction Outcomes: A Retrospective Analysis of 2.7 Million Patients.

Invasive Versus Conservative Treatment Strategy in Older Patients With Non‐ ST Segment Elevation Acute Coronary Syndromes: A Meta‐Analysis of Randomized Controlled Trials (2025)
Journal Article
Ahmed, M., Ahsan, A., Shafiq, A., Hashmi, T. M., Ahmed, R., Alam, M., Shahid, F., Rana, J. S., Mamas, M. A., & Fonarow, G. C. (in press). Invasive Versus Conservative Treatment Strategy in Older Patients With Non‐ ST Segment Elevation Acute Coronary Syndromes: A Meta‐Analysis of Randomized Controlled Trials. Journal of the American Geriatrics Society, https://doi.org/10.1111/jgs.19447

Background: Non‐ST segment elevation acute coronary syndromes (NSTE‐ACS) are a common cause of hospital admission in older patients. Our study aims to synthesize the available evidence from randomized controlled trials (RCTs) to compare clinical outc... Read More about Invasive Versus Conservative Treatment Strategy in Older Patients With Non‐ ST Segment Elevation Acute Coronary Syndromes: A Meta‐Analysis of Randomized Controlled Trials.

Cardiovascular disease burden and risk factor management in cancer survivors: insights into a multiethnic, socioeconomically deprived urban population (2025)
Journal Article
Szabo, L., Cooper, J., Condurache, D.-G., Dostal, I., Andriamiadana, G., Mathur, R., Walter, F. M., Mamas, M. A., Manisty, C. H., Harvey, N. C., Neubauer, S., Petersen, S. E., Robson, J., & Raisi-Estabragh, Z. (2025). Cardiovascular disease burden and risk factor management in cancer survivors: insights into a multiethnic, socioeconomically deprived urban population. Heart, https://doi.org/10.1136/heartjnl-2024-325309

Background: Cardiovascular disease (CVD) burden and risk factor management among cancer survivors, especially in socioeconomically deprived, multiethnic populations, remain understudied. This study examines CVD burden and risk factor control in survi... Read More about Cardiovascular disease burden and risk factor management in cancer survivors: insights into a multiethnic, socioeconomically deprived urban population.

Association of quality of care and long-term mortality risk for individuals presenting with ST-segment myocardial infarction (STEMI) by diabetes mellitus status: A nationwide cohort study (2025)
Journal Article
Cole, A., Weight, N., Wijeysundera, H. C., Rashid, M., Yu, D., Healey, E. L., Chew, N. W., Siudak, Z., Khunti, K., Kontopantelis, E., & Mamas, M. A. (in press). Association of quality of care and long-term mortality risk for individuals presenting with ST-segment myocardial infarction (STEMI) by diabetes mellitus status: A nationwide cohort study. Diabetes Research and Clinical Practice, 222, 1-10. https://doi.org/10.1016/j.diabres.2025.112092

This study aimed to assess how diabetes influences the quality of care and longer-term outcomes in contemporary STEMI cohorts. We analysed 283,658 adults hospitalised with STEMI from the United Kingdom Myocardial Ischaemia National Audit Project (MIN... Read More about Association of quality of care and long-term mortality risk for individuals presenting with ST-segment myocardial infarction (STEMI) by diabetes mellitus status: A nationwide cohort study.

Medical therapy and outcomes in REVIVED-BCIS2 and STICHES: an individual patient data analysis. (2025)
Journal Article
Ryan, M., Petrie, M. C., Kontopantelis, E., Dodd, M., Tong, G., Marquis-Gravel, G., Docherty, K. F., Clayton, T., Lansky, A. J., Mamas, M. A., Rouleau, J.-L., Velazquez, E. J., & Perera, D. (in press). Medical therapy and outcomes in REVIVED-BCIS2 and STICHES: an individual patient data analysis. European Heart Journal, 1-11. https://doi.org/10.1093/eurheartj/ehaf080

In the Surgical Treatment for Ischaemic Heart Failure Trial Extension Study (STICHES), coronary artery bypass grafting (CABG) improved outcomes of patients with ischaemic left ventricular dysfunction receiving medical therapy, whereas in the Revascul... Read More about Medical therapy and outcomes in REVIVED-BCIS2 and STICHES: an individual patient data analysis..

Quality of Care and Long-term Survival After ST-elevation Myocardial Infarction in Adults with Cancer (2025)
Journal Article
Dafaalla, M., Walter Dhillon Shanmuganathan, J., Wijeysundera, H. C., Roberts, D. J., Khan, S. U., Elbadawi, A., Elgendy, I. Y., Freeman, P., Mallen, C., & Mamas, M. A. (in press). Quality of Care and Long-term Survival After ST-elevation Myocardial Infarction in Adults with Cancer. European Heart Journal - Quality of Care and Clinical Outcomes, https://doi.org/10.1093/ehjqcco/qcaf004

Background While current evidence suggests that the clinical outcomes of ST-elevation myocardial infarction (STEMI) are worse among patients with cancer, it is unknown what role the quality of care received during admission plays. We aimed to evaluat... Read More about Quality of Care and Long-term Survival After ST-elevation Myocardial Infarction in Adults with Cancer.

Association of Kidney Function With Incident Heart Failure: An Analysis of the Women's Health Initiative. (2025)
Journal Article
Cheng, R. K., Roberts, M. B., Bansal, N., Reding, K., Salahuddin, T., Mamas, M., LaMonte, M., Shadyab, A. H., Franceschini, N., Klein, L., Manson, J. E., & Eaton, C. B. (in press). Association of Kidney Function With Incident Heart Failure: An Analysis of the Women's Health Initiative. Journal of the American Heart Association, 14(5), Article e037051. https://doi.org/10.1161/JAHA.124.037051

Studies have shown an association of chronic kidney disease with heart failure (HF); however, this association has not been adequately examined in postmenopausal women, who are at heightened risk of both chronic kidney disease and HF. Additionally, a... Read More about Association of Kidney Function With Incident Heart Failure: An Analysis of the Women's Health Initiative..

Comparative analysis of patient outcomes in pulmonary embolism with chronic inflammatory diseases. (2025)
Journal Article
Gatuz, M. V., Abu-Fanne, R., Abramov, D., Mamas, M. A., Roguin, A., & Kobo, O. (2025). Comparative analysis of patient outcomes in pulmonary embolism with chronic inflammatory diseases. IJC Heart & Vasculature, 57, Article 101637. https://doi.org/10.1016/j.ijcha.2025.101637

Pulmonary embolism (PE) is a critical condition with significant morbidity and mortality, particularly among patients with chronic inflammatory diseases (CID) such as rheumatoid arthritis and systemic lupus erythematosus that are linked to a heighten... Read More about Comparative analysis of patient outcomes in pulmonary embolism with chronic inflammatory diseases..

Immune checkpoint inhibitors: Unravelling atherosclerotic cardiovascular risk. (2025)
Journal Article
Gray, R., Manisty, C., Cheng, R., Dastidar, A., Mamas, M., & Ghosh, A. (in press). Immune checkpoint inhibitors: Unravelling atherosclerotic cardiovascular risk. Atherosclerosis, 403, Article 119147. https://doi.org/10.1016/j.atherosclerosis.2025.119147

1. Introduction
The development of immune checkpoint inhibitors (ICI) has transformed the landscape of cancer treatment in the past decade with these agents becoming the standard of care in the treatment of many malignancies [1]. There are currently... Read More about Immune checkpoint inhibitors: Unravelling atherosclerotic cardiovascular risk..

Variations in the Medical Device Authorization and Reimbursement Landscape: A Case Study of 2 Cardiovascular Devices Across 4 Countries. (2025)
Journal Article
Williams, M. M., Smith, N. R., Uyl-de Groot, C. A., den Uil, C. A., Ross, J. S., Mohamed, M. O., Mamas, M. A., Banerjee, A., Ko, D. T., Landon, B., & Cram, P. (in press). Variations in the Medical Device Authorization and Reimbursement Landscape: A Case Study of 2 Cardiovascular Devices Across 4 Countries. Circulation: Cardiovascular Quality and Outcomes, Article e011636. https://doi.org/10.1161/CIRCOUTCOMES.124.011636

The authorization process and coverage/reimbursement mechanisms for medical devices play critical roles in device adoption and usage. However, international variation in these processes remains poorly characterized, especially with regard to data tra... Read More about Variations in the Medical Device Authorization and Reimbursement Landscape: A Case Study of 2 Cardiovascular Devices Across 4 Countries..

Comparative Efficacy and Safety of Low-Dose Direct Oral Anticoagulants Versus Dual Antiplatelet Therapy Following Left Atrial Appendage Occlusion in Patients With Nonvalvular Atrial Fibrillation: A Systematic Review and Meta-Analysis. (2025)
Journal Article
Ibrahim, A., Shalabi, L., Zreigh, S., Ramadan, S., Mourad, S., Eljadid, G., Beshr, M., Abdelaziz, A., Elhadi, M., Sabouret, P., & Mamas, M. (in press). Comparative Efficacy and Safety of Low-Dose Direct Oral Anticoagulants Versus Dual Antiplatelet Therapy Following Left Atrial Appendage Occlusion in Patients With Nonvalvular Atrial Fibrillation: A Systematic Review and Meta-Analysis. Catheterization and Cardiovascular Interventions, 1-9. https://doi.org/10.1002/ccd.31461

Left atrial appendage occlusion (LAAO) is an alternative to chronic oral anticoagulation (OAT) for stroke prevention in nonvalvular atrial fibrillation (NVAF) patients with contraindications to OAT. Postprocedure antithrombotic therapy (ATT) is essen... Read More about Comparative Efficacy and Safety of Low-Dose Direct Oral Anticoagulants Versus Dual Antiplatelet Therapy Following Left Atrial Appendage Occlusion in Patients With Nonvalvular Atrial Fibrillation: A Systematic Review and Meta-Analysis..

15-Year trends, predictors, and outcomes of heart failure hospitalization complicating first acute myocardial infarction in the modern percutaneous coronary intervention era (2025)
Journal Article
Rashid, M., Abramov, D., Naseer, M. U., Van Spall, H. G. C., Ahmed, F. Z., Lawson, C., Dafaalla, M., Kontopantelis, E., Mohamed, M. O., Petrie, M. C., & Mamas, M. A. (in press). 15-Year trends, predictors, and outcomes of heart failure hospitalization complicating first acute myocardial infarction in the modern percutaneous coronary intervention era. European Heart Journal Open, 5(2), 1-11. https://doi.org/10.1093/ehjopen/oeaf013

Aims: Heart failure (HF) following acute myocardial infarction (AMI) is a global health concern, but data on risk factors associated with HF hospitalization post-AMI are limited. Methods and results: We analysed data from the Myocardial Ischaemia Nat... Read More about 15-Year trends, predictors, and outcomes of heart failure hospitalization complicating first acute myocardial infarction in the modern percutaneous coronary intervention era.

Ischemic and bleeding risk after ST-elevation myocardial infarction in patients with active cancer; a nationwide study (2025)
Journal Article
Dafaalla, M., Costa, F., Jia, H., Wijeysundera, H., Rashid, M., Graham, M. M., Wojakowski, W., Chieffo, A., Mintz, G. S., & Mamas, M. A. (in press). Ischemic and bleeding risk after ST-elevation myocardial infarction in patients with active cancer; a nationwide study. European Heart Journal Open, Article oeaf012. https://doi.org/10.1093/ehjopen/oeaf012

Background Treatment of patients with cancer presenting with ST-elevation myocardial infarction (STEMI) is complex given the increased risk of both thrombotic and major bleeding complications. Methods A nationally-linked cohort of STEMI patients betw... Read More about Ischemic and bleeding risk after ST-elevation myocardial infarction in patients with active cancer; a nationwide study.

Temporal trends in cardiovascular mortality among patients with hematological malignancies: a 20-year perspective. (2025)
Journal Article
Doolub, G., Raichman, A., Abramov, D., Bang, V., Parwani, P., Karunanithi, K., Abdel-Qadir, H., Kobo, O., & Mamas, M. A. (in press). Temporal trends in cardiovascular mortality among patients with hematological malignancies: a 20-year perspective. Expert Review of Cardiovascular Therapy, 23(1-2), 35-43. https://doi.org/10.1080/14779072.2025.2463332

We present an analysis of cardiovascular-related deaths specific to hematological cancer patients in the United States from 1999 to 2020, examining trends in relation to age, gender, and type of hematological cancer. Utilizing the Multiple Cause of D... Read More about Temporal trends in cardiovascular mortality among patients with hematological malignancies: a 20-year perspective..

Integration and Potential Applications of Cardiovascular Computed Tomography in Cardio-Oncology (2025)
Journal Article
Erbay, M. I., Manubolu, V. S., Stein-Merlob, A. F., Ferencik, M., Mamas, M. A., Lopez-Mattei, J., Baldassarre, L. A., Budoff, M. J., & Yang, E. H. (2025). Integration and Potential Applications of Cardiovascular Computed Tomography in Cardio-Oncology. Current Cardiology Reports, 27(1), 51. https://doi.org/10.1007/s11886-025-02206-x

Purpose of Review: Cardiovascular computed tomography (CCT) is a versatile, readily available, and non-invasive imaging tool with high-resolution capabilities in many cardiovascular diseases (CVD). Our review explains the increased risk of CVD among... Read More about Integration and Potential Applications of Cardiovascular Computed Tomography in Cardio-Oncology.

30-day Unplanned Readmission Rates and Causes in Patients Hospitalized for Acute Coronary Syndrome Based on DANish CoMorbidity Index for Acute Myocardial Infarction Score. (2025)
Journal Article
Sokhal, B. S., Matetić, A., Marshall, M., Twohig, H., Shepherd, T., Mallen, C. D., & Mamas, M. A. (2025). 30-day Unplanned Readmission Rates and Causes in Patients Hospitalized for Acute Coronary Syndrome Based on DANish CoMorbidity Index for Acute Myocardial Infarction Score. Hellenic Journal of Cardiology, https://doi.org/10.1016/j.hjc.2025.01.006

Introduction
This study aimed to investigate the association of the DANish CoMorbidity Index for Acute Myocardial Infarction (DANCAMI) score with 30-day unplanned readmission rates and causes in patients with acut... Read More about 30-day Unplanned Readmission Rates and Causes in Patients Hospitalized for Acute Coronary Syndrome Based on DANish CoMorbidity Index for Acute Myocardial Infarction Score..

Association of American Heart Association's Life's Essential 8 and mortality among US adults with and without cardiovascular disease. (2025)
Journal Article
Kobo, O., Kaur, G., Tamis-Holland, J. E., Zaman, S., Bullock-Palmer, R. P., Tamirisa, K., Gulati, M., & Mamas, M. A. (in press). Association of American Heart Association's Life's Essential 8 and mortality among US adults with and without cardiovascular disease. Journal of Cardiology, https://doi.org/10.1016/j.jjcc.2025.01.015

Differences in the American Heart Association's Life's Essential 8 (LE8) score and its association with mortality based on the presence of clinically prevalent cardiovascular disease (CVD) has not been assessed previously. Data from the National Heal... Read More about Association of American Heart Association's Life's Essential 8 and mortality among US adults with and without cardiovascular disease..

Corrigendum to "Adoption of same day discharge following elective left main stem percutaneous coronary intervention" [International Journal of Cardiology. 2020; 321: 38-47]. (2025)
Journal Article
Taxiarchi, P., Kontopantelis, E., Kinnaird, T., Curzen, N., Banning, A., Ludman, P., Shoaib, A., Rashid, M., Martin, G. P., & Mamas, M. A. (in press). Corrigendum to "Adoption of same day discharge following elective left main stem percutaneous coronary intervention" [International Journal of Cardiology. 2020; 321: 38-47]. International Journal of Cardiology, 423, 1. https://doi.org/10.1016/j.ijcard.2025.133010