Mamas Mamas' Outputs (897)

SEX DIFFERENCES IN DISTRIBUTION, MANAGEMENT AND OUTCOMES OF COMBINED ISCHEMIC-BLEEDING RISK FOLLOWING ACUTE CORONARY SYNDROME (2021)
Journal Article
Rashid, & Mamas. (2021). SEX DIFFERENCES IN DISTRIBUTION, MANAGEMENT AND OUTCOMES OF COMBINED ISCHEMIC-BLEEDING RISK FOLLOWING ACUTE CORONARY SYNDROME. Journal of the American College of Cardiology, 39 - 39. https://doi.org/10.1016/S0735-1097%2821%2901398-X

Background: Risk factors of bleeding and recurrent ischemic events after acute coronary syndrome (ACS) often overlap. Whether the distribution and management of these complications vary by sex remains unknown. Methods: ACS hospitalizations in the Uni... Read More about SEX DIFFERENCES IN DISTRIBUTION, MANAGEMENT AND OUTCOMES OF COMBINED ISCHEMIC-BLEEDING RISK FOLLOWING ACUTE CORONARY SYNDROME.

Clinical Outcomes of Proximal Optimization Technique (POT) in Bifurcation Stenting Short title: Impact of proximal optimization technique (2021)
Journal Article
Mamas, Rashid, & Rashid. (2021). Clinical Outcomes of Proximal Optimization Technique (POT) in Bifurcation Stenting Short title: Impact of proximal optimization technique. EuroIntervention, https://doi.org/10.4244/EIJ-D-20-01393

Background: Optimal deployment of coronary stents in a bifurcation lesion remains a matter of debate.

Aims: We sought to capture the daily practice of bifurcation stenting by means of a worldwide registry and to investigate how the post-implantati... Read More about Clinical Outcomes of Proximal Optimization Technique (POT) in Bifurcation Stenting Short title: Impact of proximal optimization technique.

Clinical outcomes of percutaneous coronary intervention for chronic total occlusion in prior coronary artery bypass grafting patients (2021)
Journal Article
Rashid, M., Shoaib, A., Mohamed, M., Curzen, N., Ludman, P., Zaman, A., Nolan, J., Azam, Z. A., Kinnaird, T., & Mamas, M. A. (2021). Clinical outcomes of percutaneous coronary intervention for chronic total occlusion in prior coronary artery bypass grafting patients. Catheterization and Cardiovascular Interventions, 99(1), 74-84. https://doi.org/10.1002/ccd.29691

OBJECTIVE: To compare the clinical characteristics and outcomes in patients with stable angina who have undergone chronic total occlusion (CTO) percutaneous coronary intervention (PCI) in native arteries with or without prior coronary artery bypass g... Read More about Clinical outcomes of percutaneous coronary intervention for chronic total occlusion in prior coronary artery bypass grafting patients.

Prognosis of Acute Ischaemic Stroke Patients with Cancer: A National Inpatient Sample Study (2021)
Journal Article
Mamas. (2021). Prognosis of Acute Ischaemic Stroke Patients with Cancer: A National Inpatient Sample Study. Cancers, 2193 - 2193. https://doi.org/10.3390/cancers13092193

Whilst cancer is a risk factor for acute ischaemic stroke (AIS), its impact on AIS prognosis between metastatic and non-metastatic (MC and NMC) disease is poorly understood. Furthermore, the receipt of intravenous thrombolysis (IVT) and endovascular... Read More about Prognosis of Acute Ischaemic Stroke Patients with Cancer: A National Inpatient Sample Study.

HYBRID CORONARY REVASCULARIZATION VERSUS CORONARY ARTERY BYPASS GRAFT IN PATIENTS WITH MULTIVESSEL CORONARY ARTERY DISEASE A META-ANALYSIS (2021)
Journal Article
Zghouzi, M., Ullah, W., Sandhyavenu, H., Pacha, H. M., Al-Khadra, Y., Ahmad, B., Sattar, Y., Suleiman, A.-R., Garcia, S., Bagur, R., Ali, O., Gardi, D., Hakim, Z., Mohamed, M., Rashid, M., Mamas, M., & Alraies, M. C. (2021). HYBRID CORONARY REVASCULARIZATION VERSUS CORONARY ARTERY BYPASS GRAFT IN PATIENTS WITH MULTIVESSEL CORONARY ARTERY DISEASE A META-ANALYSIS. Journal of the American College of Cardiology, 77(18), 1042. https://doi.org/10.1016/s0735-1097%2821%2902401-3

Background
Hybrid coronary artery revascularization (HCR) refers to complete or near complete revascularization using the combination of single vessel CABG and PCI of other significant coronary lesions. The short-term outcomes of HCR compared to CAB... Read More about HYBRID CORONARY REVASCULARIZATION VERSUS CORONARY ARTERY BYPASS GRAFT IN PATIENTS WITH MULTIVESSEL CORONARY ARTERY DISEASE A META-ANALYSIS.

META-ANALYSIS OF SAFETY AND EFFICACY OF RENIN ANGIOTENSIN ALDOSTERONE SYSTEM INHIBITORS IN COVID-19 POPULATION (2021)
Presentation / Conference Contribution
Sattar, Y., Mukuntharaj, P., Attique, H., Ullah, W., Sana, M. K., Zaher, N., Suleiman, A.-R. M., Mehmood, M., Panchal, A., Mir, T., Nadeem, M., Zghouzi, M., Ahmad, B., Hakim, Z., Gardi, D., Ali, O. E., Alhatemi, G., Mohamed, M., Elgendy, I., Mamas, M., & Alraies, M. C. META-ANALYSIS OF SAFETY AND EFFICACY OF RENIN ANGIOTENSIN ALDOSTERONE SYSTEM INHIBITORS IN COVID-19 POPULATION. Presented at ACC.21

Background
The safety and efficacy of Renin Angiotensin Aldosterone System Inhibitors(RAASi) in COVID 19 patients has been controversial.

Methods
Digital databases were queried for relevant articles. A random-effect model was used to compute an... Read More about META-ANALYSIS OF SAFETY AND EFFICACY OF RENIN ANGIOTENSIN ALDOSTERONE SYSTEM INHIBITORS IN COVID-19 POPULATION.

THE ASSOCIATION BETWEEN SEX, RACE, SOCIOECONOMIC STATUS, AND IN-HOSPITAL ALL-CAUSE MORTALITY AMONG PATIENTS ADMITTED FOR HEART FAILURE: A RETROSPECTIVE COHORT STUDY (2021)
Presentation / Conference Contribution
Averbuch, T., Mohamed, M., Islam, S., Martin, G., Thabane, L., Mamas, M., & Van Spall, H. G. THE ASSOCIATION BETWEEN SEX, RACE, SOCIOECONOMIC STATUS, AND IN-HOSPITAL ALL-CAUSE MORTALITY AMONG PATIENTS ADMITTED FOR HEART FAILURE: A RETROSPECTIVE COHORT STUDY. Presented at ACC.21; 15-17 May 2021, Virtual

Background
Heart failure (HF) hospitalization is associated with high mortality. We aimed to assess the role of race, sex, and socioeconomic status (SES) in the risk of in-hospital mortality among patients hospitalized for HF.

Methods
We used th... Read More about THE ASSOCIATION BETWEEN SEX, RACE, SOCIOECONOMIC STATUS, AND IN-HOSPITAL ALL-CAUSE MORTALITY AMONG PATIENTS ADMITTED FOR HEART FAILURE: A RETROSPECTIVE COHORT STUDY.

Clinical phenogroups are more effective than left ventricular ejection fraction categories in stratifying heart failure outcomes (2021)
Journal Article
Gevaert, A. B., Tibebu, S., Mamas, M. A., Ravindra, N. G., Lee, S. F., Ahmad, T., Ko, D. T., Januzzi, J. L., & Van Spall, H. G. (2021). Clinical phenogroups are more effective than left ventricular ejection fraction categories in stratifying heart failure outcomes. ESC Heart Failure, 8(4), 2741-2754. https://doi.org/10.1002/ehf2.13344

Aims
Heart failure (HF) guidelines place patients into 3 discrete groups according to left ventricular ejection fraction (LVEF): reduced (<40%), mid-range (40–49%), and preserved LVEF (=50%). We assessed whether clinical phenogroups offer better pro...

Derivation and validation of a two-variable index to predict 30-day outcomes following heart failure hospitalization (2021)
Journal Article
Mamas, Averbuch, T., Lee, S. F., Mamas, M. A., Oz, U. E., Perez, R., Connolly, S. J., Ko, D. T., & Van Spall, H. G. C. (2021). Derivation and validation of a two-variable index to predict 30-day outcomes following heart failure hospitalization. ESC Heart Failure, 8(4), 2690-2697. https://doi.org/10.1002/ehf2.13324

Background
The LACE index—length of stay (L), acuity (A), Charlson co-morbidities (C), and emergent visits (E)—predicts 30-day outcomes following heart failure (HF) hospitalization but is complex to score. A simpler LE index (length of stay and emer... Read More about Derivation and validation of a two-variable index to predict 30-day outcomes following heart failure hospitalization.

Ethnic disparities in care and outcomes of non-ST-segment elevation myocardial infarction: a nationwide cohort study. (2021)
Journal Article
Mamas, & Rashid. (2021). Ethnic disparities in care and outcomes of non-ST-segment elevation myocardial infarction: a nationwide cohort study. European Heart Journal - Quality of Care and Clinical Outcomes, https://doi.org/10.1093/ehjqcco/qcab030

BACKGROUND: Little is known about ethnic disparities in care and clinical outcomes of patients admitted with non-ST-segment elevation myocardial infarction (NSTEMI) in national cohorts from universal healthcare systems derived from Europe. METHODS &... Read More about Ethnic disparities in care and outcomes of non-ST-segment elevation myocardial infarction: a nationwide cohort study..

Assessing the severity of cardiovascular disease in 213 088 patients with coronary heart disease: a retrospective cohort study. (2021)
Journal Article
Mamas, Mallen, & Chew-Graham. (2021). Assessing the severity of cardiovascular disease in 213 088 patients with coronary heart disease: a retrospective cohort study. Open Heart, https://doi.org/10.1136/openhrt-2020-001498

OBJECTIVE: Most current cardiovascular disease (CVD) risk stratification tools are for people without CVD, but very few are for prevalent CVD. In this study, we developed and validated a CVD severity score in people with coronary heart disease (CHD)... Read More about Assessing the severity of cardiovascular disease in 213 088 patients with coronary heart disease: a retrospective cohort study..

In-Hospital Outcomes and Trends of Endovascular Intervention vs Surgical Revascularization in Octogenarians With Peripheral Artery Disease. (2021)
Journal Article
Mamas. (2021). In-Hospital Outcomes and Trends of Endovascular Intervention vs Surgical Revascularization in Octogenarians With Peripheral Artery Disease. American Journal of Cardiology, 143 - 150

It is unknown whether endovascular intervention (EVI) is associated with superior outcomes when compared with surgical revascularization in octogenarian. National Inpatient Sample (NIS) database was used to compare the outcomes of limb revascularizat... Read More about In-Hospital Outcomes and Trends of Endovascular Intervention vs Surgical Revascularization in Octogenarians With Peripheral Artery Disease..

Cost of inpatient heart failure care and 30-day readmissions in the United States (2021)
Journal Article
Mamas, Kwok, C. S., Abramov, D., Parwani, P., Ghosh, R. K., Kittleson, M., Ahmad, F. Z., Al Ayoubi, F., & Van Spall, H. G. C. (2021). Cost of inpatient heart failure care and 30-day readmissions in the United States. International Journal of Cardiology, 329, 115-122. https://doi.org/10.1016/j.ijcard.2020.12.020

BACKGROUND: Heart failure hospitalizations are a major financial cost to healthcare systems. This study aimed to evaluate the costs associated with inpatient hospitalization. METHODS: Patients with a primary diagnosis of heart failure during a hospit... Read More about Cost of inpatient heart failure care and 30-day readmissions in the United States.

Distribution of High-Sensitivity Troponin Taken Without Conventional Clinical Indications in Critical Care Patients and Its Association With Mortality. (2021)
Journal Article
Mamas, M., Hinton, J., Augustine, M., Gabara, L., Mariathas, M., Allan, R., Borca, F., Nicholas, Z., Beecham, R., Gillett, N., Kwok, C. S., Cook, P., Grocott, M. P. W., & Curzen, N. (2021). Distribution of High-Sensitivity Troponin Taken Without Conventional Clinical Indications in Critical Care Patients and Its Association With Mortality. Critical Care Medicine, 49(9), 1451 - 1459. https://doi.org/10.1097/ccm.0000000000005024

OBJECTIVES: To describe the distribution of high-sensitivity troponin in a consecutive cohort of patients in critical care units, regardless of clinical indication, and its association with clinical outcomes. DESIGN: Prospective observational study.... Read More about Distribution of High-Sensitivity Troponin Taken Without Conventional Clinical Indications in Critical Care Patients and Its Association With Mortality..

Evidence-based arterial access site practice in patients with acute coronary syndromes: Has SAFARI-STEMI changed the landscape? (2021)
Journal Article
Nagaraja, V., Rao, S. V., George, S., Mamas, M., & Nolan, J. (2021). Evidence-based arterial access site practice in patients with acute coronary syndromes: Has SAFARI-STEMI changed the landscape?. Catheterization and Cardiovascular Interventions, 97(7), 1417 - 1421. https://doi.org/10.1002/ccd.29684

Key Points Access site practice in acute coronary syndrome (ACS) has been extensively investigated with the data favoring a radial approach. SAFARI‐STEMI does not change the recommendation to use radial access in most patients due to methodological i... Read More about Evidence-based arterial access site practice in patients with acute coronary syndromes: Has SAFARI-STEMI changed the landscape?.

Clinical and Economic Burden of Stroke Among Young, Midlife, and Older Adults in the United States, 2002-2017 (2021)
Journal Article
Mamas, & Rashid. (2021). Clinical and Economic Burden of Stroke Among Young, Midlife, and Older Adults in the United States, 2002-2017. https://doi.org/10.1016/j.mayocpiqo.2021.01.015

Objective
To assess trends of stroke hospitalization rates, inpatient mortality, and health care resource use in young (aged =44 years), midlife (aged 45-64 years), and older (aged =65 years) adults.

Patients and Methods
We studied the National... Read More about Clinical and Economic Burden of Stroke Among Young, Midlife, and Older Adults in the United States, 2002-2017.

Questions and answers on antithrombotic therapy and revascularization strategies in non-ST-elevation acute coronary syndrome (NSTE-ACS): a companion document of the 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. (2021)
Journal Article
Barbato, E., Mehilli, J., Sibbing, D., Siontis, G. C. M., Collet, J.-P., Thiele, H., Scientific Document Group, E., & Mamas, M. (2021). Questions and answers on antithrombotic therapy and revascularization strategies in non-ST-elevation acute coronary syndrome (NSTE-ACS): a companion document of the 2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. European Heart Journal, 1368 - 1378. https://doi.org/10.1093/eurheartj/ehaa601

Machine Learning-Augmented Propensity Score Analysis of Percutaneous Coronary Intervention in Over 30 Million Cancer and Non-cancer Patients. (2021)
Journal Article
Mamas. (2021). Machine Learning-Augmented Propensity Score Analysis of Percutaneous Coronary Intervention in Over 30 Million Cancer and Non-cancer Patients. Frontiers in Cardiovascular Medicine, -. https://doi.org/10.3389/fcvm.2021.620857

Background: It is unknown to what extent the clinical benefits of PCI outweigh the risks and costs in patients with vs. without cancer and within each cancer type. We performed the first known nationally representative propensity score analysis of PC... Read More about Machine Learning-Augmented Propensity Score Analysis of Percutaneous Coronary Intervention in Over 30 Million Cancer and Non-cancer Patients..

Thin Strut CoCr Biodegradable Polymer Biolimus A9-Eluting Stents versus Thicker Strut Stainless Steel Biodegradable Polymer Biolimus A9-Eluting Stents: Two-Year Clinical Outcomes. (2021)
Journal Article
Mamas. (2021). Thin Strut CoCr Biodegradable Polymer Biolimus A9-Eluting Stents versus Thicker Strut Stainless Steel Biodegradable Polymer Biolimus A9-Eluting Stents: Two-Year Clinical Outcomes. Journal of Interventional Cardiology, https://doi.org/10.1155/2021/6654515

Background: While thinner struts are associated with improved clinical outcomes in bare-metal stents (BMS), reducing strut thickness may affect drug delivery from drug-eluting stents (DES) and there are limited data comparing otherwise similar thin a... Read More about Thin Strut CoCr Biodegradable Polymer Biolimus A9-Eluting Stents versus Thicker Strut Stainless Steel Biodegradable Polymer Biolimus A9-Eluting Stents: Two-Year Clinical Outcomes..

Location of death among patients presenting with cardiovascular disease to the emergency department in the United states. (2021)
Journal Article
Mamas. (2021). Location of death among patients presenting with cardiovascular disease to the emergency department in the United states. https://doi.org/10.1111/ijcp.13798

BACKGROUND: In-hospital deaths are an important outcome and little is known about deaths in the emergency department (ED). Among patients who died of cardiovascular diseases (CVD), we assessed causes of death, temporal trends and the relative distrib... Read More about Location of death among patients presenting with cardiovascular disease to the emergency department in the United states..