Outputs (2)

Biogenic metallic elements in the human brain? (2021)
Journal Article
Everett, J., Lermyte, F., Brooks, J., Tjendana-Tjhin, V., Plascencia-Villa, G., Hands-Portman, I., …Telling, N. D. (2021). Biogenic metallic elements in the human brain?. Science Advances, 7(24), https://doi.org/10.1126/sciadv.abf6707

The chemistry of copper and iron plays a critical role in normal brain function. A variety of enzymes and proteins containing positively charged Cu+, Cu2+, Fe2+, and Fe3+ control key processes, catalyzing oxidative metabolism and neurotransmitter and... Read More about Biogenic metallic elements in the human brain?.

Nanoscale chemical speciation of ß-amyloid/iron aggregates using soft x-ray spectromicroscopy (2021)
Journal Article
Everett, J., Brooks, J., Collingwood, J. F., & Telling, N. (2021). Nanoscale chemical speciation of ß-amyloid/iron aggregates using soft x-ray spectromicroscopy. Inorganic Chemistry Frontiers, 8(6), 1439-1448. https://doi.org/10.1039/D0QI01304H

Iron (Fe) is an essential trace element required for healthy brain function. Yet, disrupted iron neurochemistry, and the associated formation of aberrantly aggregated protein lesions has been implicated in the development of multiple degenerative bra... Read More about Nanoscale chemical speciation of ß-amyloid/iron aggregates using soft x-ray spectromicroscopy.