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Outputs (156)

Bisphosphonate alternative regimens for the prevention of osteoporotic fragility fractures: BLAST-OFF, a mixed-methods study (2024)
Report

Bisphosphonates are a class of medication commonly used to treat osteoporosis. Alendronate is recommended as the first-line treatment; however, long-term adherence (both treatment compliance and persistence) is poor. Alternative bisphosphonates are a... Read More about Bisphosphonate alternative regimens for the prevention of osteoporotic fragility fractures: BLAST-OFF, a mixed-methods study.

P080 Supporting shared decision-making about osteoporosis medicines: Combining multiple methods to develop the prototype iFraP intervention (2024)
Presentation / Conference

Background/Aims Shared decision-making (SDM) is a joint process in which a person and healthcare professional work together to reach decisions about care. The iFraP (Improving uptake of Fracture Prevention drug treatments) intervention comprises comp... Read More about P080 Supporting shared decision-making about osteoporosis medicines: Combining multiple methods to develop the prototype iFraP intervention.

Daily Pain Severity but Not Vertebral Fractures Is Associated With Lower Physical Activity in Postmenopausal Women With Back Pain (2024)
Journal Article

Back pain lifetime incidence is 60-70%, whilst 12-20% of older women have vertebral fractures (VFs), often with back pain. We aimed to provide objective evidence, currently lacking, regarding whether back pain and VFs affect physical activity (PA).... Read More about Daily Pain Severity but Not Vertebral Fractures Is Associated With Lower Physical Activity in Postmenopausal Women With Back Pain.

Improving patients’ experiences of diagnosis and treatment of vertebral fracture: co-production of knowledge sharing resources (2024)
Journal Article

Background: Osteoporosis involves changes to bones that makes them prone to fracture. The most common osteoporotic fracture is vertebral, in which one or more spinal vertebrae collapse. People with vertebral fracture are at high risk of further fract... Read More about Improving patients’ experiences of diagnosis and treatment of vertebral fracture: co-production of knowledge sharing resources.

An online clinical decision tool to screen for vertebral fragility fractures (Vfrac) in older women presenting with back pain in general practice: protocol for a feasibility study in preparation for a future cluster randomised controlled trial (2024)
Journal Article

Summary: This feasibility study for a future definitive randomized trial assesses the use and acceptability of a new clinical decision tool to identify risk of a vertebral fracture and those who should be referred for spinal radiography in women aged... Read More about An online clinical decision tool to screen for vertebral fragility fractures (Vfrac) in older women presenting with back pain in general practice: protocol for a feasibility study in preparation for a future cluster randomised controlled trial.

An online clinical decision tool to screen for vertebral fragility fractures (Vfrac) in older women presenting with back pain in general practice: protocol for a feasibility study in preparation for a future cluster randomized controlled trial (2024)
Journal Article

Summary This feasibility study for a future definitive randomized trial assesses the use and acceptability of a new clinical decision tool to identify risk of a vertebral fracture and those who should be referred for spinal radiography in women aged... Read More about An online clinical decision tool to screen for vertebral fragility fractures (Vfrac) in older women presenting with back pain in general practice: protocol for a feasibility study in preparation for a future cluster randomized controlled trial.

Optimising the implementation of evidence-based osteoarthritis guidelines in primary care: Development of a knowledge mobilisation toolkit (2024)
Journal Article

Objective Implementing clinical guidelines for osteoarthritis in primary care is complex. Whilst international guidelines detail what best practice for osteoarthritis looks like, little is known about how this is... Read More about Optimising the implementation of evidence-based osteoarthritis guidelines in primary care: Development of a knowledge mobilisation toolkit.

Variation in UK fracture liaison service consultation conduct and content before and during the COVID pandemic: results from the iFraP-D UK survey (2023)
Journal Article

Summary We conducted a survey of FLSs’ consultation conduct and content which identified marked variation in whether FLS HCPs discussed osteoporosis medicine with patients. A review of service pro formas showed more content related to ‘investigating... Read More about Variation in UK fracture liaison service consultation conduct and content before and during the COVID pandemic: results from the iFraP-D UK survey.

The cost-effectiveness of adding an ultrasound corticosteroid and local anaesthetic injection to advice and education for hip osteoarthritis (2023)
Journal Article

Objectives. Evidence for the comparative cost-effectiveness of intra-articular corticosteroid injection in people with hip osteoarthritis (OA) remains unclear. This study investigated the cost-effectiveness of best current treatment (BCT) comprising... Read More about The cost-effectiveness of adding an ultrasound corticosteroid and local anaesthetic injection to advice and education for hip osteoarthritis.

Using the UK standards for public involvement to evaluate the public involvement sections of annual reports from NIHR managed research centres (2023)
Journal Article

Background: Within the United Kingdom (UK), the National Institute for Health and Care Research is the largest funder of health and social care research, and additionally funds research centres that support the development and delivery of research. E... Read More about Using the UK standards for public involvement to evaluate the public involvement sections of annual reports from NIHR managed research centres.

Patients' preferences for fracture risk communication: the Risk Communication in Osteoporosis (RICO) study. (2023)
Journal Article

The RICO study indicated that most patients would like to receive information regarding their fracture risk but that only a small majority have actually received it. Patients globally preferred a visual presentation of fracture risk and were interest... Read More about Patients' preferences for fracture risk communication: the Risk Communication in Osteoporosis (RICO) study..

Rheumatology nurses' perceptions of undertaking a postgraduate education programme: A phenomenological study (2023)
Journal Article

Background: The expansion of the role of the rheumatology nurse specialist led to the instigation, in 1999, of the first Masters programme in rheumatology nursing, with the aim of supporting clinical advancement with evidence‐based practice. This stu... Read More about Rheumatology nurses' perceptions of undertaking a postgraduate education programme: A phenomenological study.

Clinicians’ views of prescribing oral and intravenous bisphosphonates for osteoporosis: a qualitative study (2023)
Journal Article

Background: Bisphosphonate medications, including alendronate, ibandronate and risedronate administered orally and zoledronate, administered intravenously, are commonly prescribed for the treatment of osteoporosis based on evidence that, correctly ta... Read More about Clinicians’ views of prescribing oral and intravenous bisphosphonates for osteoporosis: a qualitative study.

Bone health assessment in adults with fragility fracture risk factors between 2002-2014: a retrospective cohort study. (2023)
Journal Article

Background Lifetime risk of fragility fractures is 50% in post-menopausal women and 20% in men aged over 50 years. Identifying people at high risk facilitates early intervention and reduction of biopsychosocial morbidity associated with these fractur... Read More about Bone health assessment in adults with fragility fracture risk factors between 2002-2014: a retrospective cohort study..

Applying the consolidated framework for implementation research to evaluate the community rapid intervention service (2023)
Journal Article

Background: Developed in 2019, the Community Rapid Intervention Service (CRIS) is a community intervention service aiming to prevent hospital admissions. CRIS provides a response within two hours to patients with sub-acute medical needs in their usua... Read More about Applying the consolidated framework for implementation research to evaluate the community rapid intervention service.

Osteoporosis and fracture as risk factors for self-harm and suicide: a systematic review and meta-analysis (2023)
Journal Article

Background: Increase in presentations of self-harm to primary care, a risk factor of suicide, has led to a growing interest in identifying at-risk populations. Aim: To examine whether osteoporosis or fractures are risk factors for self-harm, sui... Read More about Osteoporosis and fracture as risk factors for self-harm and suicide: a systematic review and meta-analysis.

Exploring the treatment burden of disease modifying anti rheumatic drug monitoring in people with rheumatoid arthritis (2023)
Journal Article

Objectives People with rheumatoid arthritis (RA) taking disease-modifying anti-rheumatic drugs (DMARDs) require safety monitoring to identify potential side-effects. This study aimed to explore patients’ and family members’ perspectives on DMARD moni... Read More about Exploring the treatment burden of disease modifying anti rheumatic drug monitoring in people with rheumatoid arthritis.

Research priorities regarding the use of bisphosphonates for osteoporosis: a UK priority setting exercise (2023)
Journal Article

Worldwide, many people who would benefit from osteoporosis drugs are not offered or receiving them, resulting in an osteoporosis care gap. Adherence with bisphosphonates is particularly low. This study aimed to identify stakeholder research prioritie... Read More about Research priorities regarding the use of bisphosphonates for osteoporosis: a UK priority setting exercise.

AB1595 HOW DO WE PREVENT THE DEVELOPMENT OF MULTIMORBIDITY IN PEOPLE WITH INFLAMMATORY RHEUMATOLOGICAL DISORDERS: A QUALITATIVE INVESTIGATION (2023)
Journal Article

Background: People with inflammatory rheumatological disorders (IRDs) are at high risk of developing multimorbidity, specifically cardiovascular disease (CVD) and mood problems. UK guidelines advocate annual reviews for people with Rheumatoid Arthrit... Read More about AB1595 HOW DO WE PREVENT THE DEVELOPMENT OF MULTIMORBIDITY IN PEOPLE WITH INFLAMMATORY RHEUMATOLOGICAL DISORDERS: A QUALITATIVE INVESTIGATION.

E060 Testing a new prototype osteoporosis shared decision-making intervention in UK Fracture Liaison Services: patient and clinician perspectives of ‘iFraP’ (2023)
Presentation / Conference

Shared decision-making (SDM) is a joint process in which a person and healthcare professional work together to reach decisions about care. The Improving uptake of Fracture Prevention drug treatments (iFraP) study developed a prototype theoretically-i... Read More about E060 Testing a new prototype osteoporosis shared decision-making intervention in UK Fracture Liaison Services: patient and clinician perspectives of ‘iFraP’.

Exploring the longer-term impact of the COVID-19 pandemic on physical and mental health of people with inflammatory rheumatic diseases: a cross-sectional survey (2023)
Journal Article

OBJECTIVE: To assess the longer term impact of the COVID-19 pandemic on the self-reported physical and mental health of people with inflammatory rheumatic diseases (IRDs). METHODS: Two thousand twenty-four patients with IRDs were randomly selected fr... Read More about Exploring the longer-term impact of the COVID-19 pandemic on physical and mental health of people with inflammatory rheumatic diseases: a cross-sectional survey.

Optimising the process of knowledge mobilisation in Communities of Practice: recommendations from a (multi-method) qualitative study (2023)
Journal Article

Background: Communities of Practice (CoPs) offer a strategy for mobilising knowledge and integrating evidence-based interventions into musculoskeletal practice, yet little is known about their practical application in this context. This study aimed t... Read More about Optimising the process of knowledge mobilisation in Communities of Practice: recommendations from a (multi-method) qualitative study.

Digital exclusion as a potential cause of inequalities in access to care: a survey in people with inflammatory rheumatic diseases (2023)
Journal Article

Objectives: COVID-19 led to rapid uptake of digital healthcare. We sought to examine digital access, health and digital literacy, and impact on confidence and satisfaction with remote consultations in people with inflammatory rheumatic diseases (IRDs... Read More about Digital exclusion as a potential cause of inequalities in access to care: a survey in people with inflammatory rheumatic diseases.

Acceptability and engagement amongst patients on oral and intravenous bisphosphonates for the treatment of osteoporosis in older adults (2022)
Journal Article

Background: Osteoporosis is common in older adults leading to fragility fractures at enormous individual and economic cost. Improving long-term adherence with bisphosphonate treatments reduces fracture risk, but adherence rates for first line oral bi... Read More about Acceptability and engagement amongst patients on oral and intravenous bisphosphonates for the treatment of osteoporosis in older adults.

Research priorities to reduce the impact of Musculoskeletal Disorders: a priority setting exercise using the CHRNI method (2022)
Journal Article

Involving research users in setting priorities for research is essential to ensure research outcomes are patient-centred and to maximise research value and impact. The Musculoskeletal (MSK) Disorders Research Advisory Group Versus Arthritis led a res... Read More about Research priorities to reduce the impact of Musculoskeletal Disorders: a priority setting exercise using the CHRNI method.

Exploring the physical, psychological and social well-being of people with rheumatoid arthritis during the coronavirus pandemic: a single-centre, longitudinal, qualitative interview study in the UK (2022)
Journal Article

Objective Rheumatoid arthritis (RA) is an autoimmune, inflammatory, systemic condition that requires specific drug treatment to suppress disease activity and prevent joint deformity. To manage the ongoing symptoms of joint pain and fatigue patients a... Read More about Exploring the physical, psychological and social well-being of people with rheumatoid arthritis during the coronavirus pandemic: a single-centre, longitudinal, qualitative interview study in the UK.

Exploring the physical, psychological and social well-being of people with rheumatoid arthritis during the coronavirus pandemic: a single-centre, longitudinal, qualitative interview study in the UK (2022)
Journal Article

OBJECTIVE: Rheumatoid arthritis (RA) is an autoimmune, inflammatory, systemic condition that requires specific drug treatment to suppress disease activity and prevent joint deformity. To manage the ongoing symptoms of joint pain and fatigue patients... Read More about Exploring the physical, psychological and social well-being of people with rheumatoid arthritis during the coronavirus pandemic: a single-centre, longitudinal, qualitative interview study in the UK.

Supporting patients to get the best from their osteoporosis treatment; what works for whom, why and in what circumstance: a rapid realist review (2022)
Journal Article

Purpose: In people with osteoporosis, adherence to medicines is poorer than other diseases and patients report follow up is lacking, and multiple unmet information needs. We conducted a rapid realist review to understand what contextual conditions an... Read More about Supporting patients to get the best from their osteoporosis treatment; what works for whom, why and in what circumstance: a rapid realist review.

Supporting patients to get the best from their osteoporosis treatment: a rapid realist review of what works, for whom, and in what circumstance (2022)
Journal Article

Systematic reviews that examine effectiveness of interventions to improve medicines optimisation do not explain how or why they work. This realist review identified that interventions which effectively optimise medicines use in osteoporosis include o... Read More about Supporting patients to get the best from their osteoporosis treatment: a rapid realist review of what works, for whom, and in what circumstance.

POS1514-HPR UNDERSTANDING AND CHARACTERISING PATIENT PATHWAYS TO TREATMENT FOR VERTEBRAL FRACTURES: A QUALITATIVE STUDY (2022)
Journal Article

BackgroundOsteoporosis involves thinning of the bones, making them more prone to break. The most common osteoporotic fracture is a vertebral fracture (OVF). People with OVFs are at high risk of further fractures. To reduce this risk, guidelines recom... Read More about POS1514-HPR UNDERSTANDING AND CHARACTERISING PATIENT PATHWAYS TO TREATMENT FOR VERTEBRAL FRACTURES: A QUALITATIVE STUDY.

Strong, Steady and Straight: UK consensus statement on physical activity and exercise for osteoporosis (2022)
Journal Article

Exercise and physical activity can improve bone strength and the risk of falls, which may offer benefits in the prevention and management of osteoporosis. However, uncertainty about the types of exercise that are safe and effective instigates lack of... Read More about Strong, Steady and Straight: UK consensus statement on physical activity and exercise for osteoporosis.

P077 Developing a better explanation of osteoarthritis: results from a conjoint analysis of patient preferences (2022)
Journal Article

Abstract Background/Aims Despite the negative impact of osteoarthritis (OA) and existence of evidence-based guidelines, many patients and professionals lack clarity about the nature of OA and effective treatment strategies. This project aims to impr... Read More about P077 Developing a better explanation of osteoarthritis: results from a conjoint analysis of patient preferences.

P059 Acceptability of remote consulting during COVID-19 among patients with two common long-term musculoskeletal conditions: findings from three qualitative studies and recommendations for practice (2022)
Journal Article

Abstract Background/Aims The COVID-19 pandemic led to the widespread adoption of remote consultations. Whilst remote consultations offer many potential advantages to patients and healthcare services, they are unlikely to be suitable for all. Guidanc... Read More about P059 Acceptability of remote consulting during COVID-19 among patients with two common long-term musculoskeletal conditions: findings from three qualitative studies and recommendations for practice.

P064 Impact of COVID-19 on physical and mental health of people with inflammatory conditions: the ICEPAC survey (2022)
Journal Article

Abstract Background/Aims Concerns about the risk of COVID-19 infection led to guidelines advocating shielding for many people with inflammatory conditions. We aimed to assess the impact of the pandemic on the self-reported physical and mental health... Read More about P064 Impact of COVID-19 on physical and mental health of people with inflammatory conditions: the ICEPAC survey.

P091 Who do we risk leaving behind? A survey of digital access and e-health literacy in people with inflammatory conditions (2022)
Journal Article

Abstract Background/Aims The COVID-19 pandemic led to an overnight shift in healthcare delivery and rapid uptake of digital technology. Such approaches risk digital exclusion for people without access to or not confident in their use of technology.... Read More about P091 Who do we risk leaving behind? A survey of digital access and e-health literacy in people with inflammatory conditions.

P137 Supporting patients to get the best from their osteoporosis treatment; what works for whom, why and in what circumstance: a rapid realist review (2022)
Journal Article

Abstract Background/Aims For two decades, clinicians and academics have been writing about the problem of poor adherence in osteoporosis, while people with osteoporosis have identified a need for more follow up and information about medicines. We ai... Read More about P137 Supporting patients to get the best from their osteoporosis treatment; what works for whom, why and in what circumstance: a rapid realist review.

P008 Fracture liaison service management of patients aged 85 and older who sustain fragility fractures: audit and quality improvement (2022)
Journal Article

Abstract Background/Aims Osteoporosis is a burdensome disease internationally, that is commonly diagnosed following fragility fracture. In line with national guidance, in 2018 the North Staffordshire Fracture Liaison Service (FLS) changed their mana... Read More about P008 Fracture liaison service management of patients aged 85 and older who sustain fragility fractures: audit and quality improvement.

Overall Effects and Moderators of Rehabilitation in Patients With Wrist Fracture: A Systematic Review. (2022)
Journal Article

OBJECTIVE: Wrist fractures constitute the most frequently occurring upper limb fracture. Many patients report persistent pain and functional limitations up to 18 months following wrist fracture. Identifying which patients are likely to gain the great... Read More about Overall Effects and Moderators of Rehabilitation in Patients With Wrist Fracture: A Systematic Review..

Clinical effectiveness of one ultrasound guided intra-articular corticosteroid and local anaesthetic injection in addition to advice and education for hip osteoarthritis (HIT trial): single blind, parallel group, three arm, randomised controlled trial (2022)
Journal Article

Objectives: to compare the clinical effectiveness of best current treatment (BCT) plus single ultrasound-guided intra-articular hip injection (USGI) of 40mg triamcinolone acetonide and 4ml 1% lidocaine hydrochloride [BCT+US-Triamcinolone-Lidocaine] w... Read More about Clinical effectiveness of one ultrasound guided intra-articular corticosteroid and local anaesthetic injection in addition to advice and education for hip osteoarthritis (HIT trial): single blind, parallel group, three arm, randomised controlled trial.

Acceptability of, and preferences for, remote consulting during COVID-19 among older patients with two common long-term musculoskeletal conditions: findings from three qualitative studies and recommendations for practice (2022)
Journal Article

Background Guidance for choosing face-to-face vs remote consultations (RCs) encourages clinicians to consider patient preferences, however, little is known about acceptability of, and preferences for RCs, particularly amongst patients with musculoske... Read More about Acceptability of, and preferences for, remote consulting during COVID-19 among older patients with two common long-term musculoskeletal conditions: findings from three qualitative studies and recommendations for practice.

TREATMENT ACCEPTABILITY AND ENGAGEMENT AMONGST PATIENTS ON ORAL AND INTRAVENOUS BISPHOSPHONATES: A QUALITATIVE STUDY (2022)
Presentation / Conference

Objective: To explore treatment acceptability and engagement amongst patients prescribed oral and intravenous bisphosphonate treatment regimens for the prevention of osteoporotic fragility fractures. Methods: Semistructured interviews were conduct... Read More about TREATMENT ACCEPTABILITY AND ENGAGEMENT AMONGST PATIENTS ON ORAL AND INTRAVENOUS BISPHOSPHONATES: A QUALITATIVE STUDY.

A clinical tool to identify older women with back pain at high risk of osteoporotic vertebral fractures (Vfrac): a population-based cohort study with exploratory economic evaluation (2022)
Journal Article

Background: Osteoporotic vertebral fractures (OVFs) identify people at high risk of future fractures, but despite this, less than a third come to clinical attention. The objective of this study was to develop a clinical tool to aid healthcare profess... Read More about A clinical tool to identify older women with back pain at high risk of osteoporotic vertebral fractures (Vfrac): a population-based cohort study with exploratory economic evaluation.

Assessing the Effectiveness of Bisphosphonates for the Prevention of Fragility Fractures: An Updated Systematic Review and Network Meta‐Analyses (2022)
Journal Article

Bisphosphonates have been found to be effective in preventing fragility fractures. However, their comparative effectiveness in populations at risk has yet to be defined. In light of recent clinical trials, we aimed to compare four bisphosphonates (al... Read More about Assessing the Effectiveness of Bisphosphonates for the Prevention of Fragility Fractures: An Updated Systematic Review and Network Meta‐Analyses.

Comparing medication adherence in patients receiving bisphosphonates for preventing fragility fractures: a comprehensive systematic review and network meta-analysis. (2022)
Journal Article

BACKGROUND: Bisphosphonates are effective in preventing fragility fractures; however, high rates of adherence are needed to preserve clinical benefits. OBJECTIVE: To investigate persistence and compliance to oral and intravenous bisphosphonates (alen... Read More about Comparing medication adherence in patients receiving bisphosphonates for preventing fragility fractures: a comprehensive systematic review and network meta-analysis..

Addition of symptoms to traditional risk factors improves prediction of those at high risk of vertebral fractures: Results of the Vfrac study (2022)
Journal Article

Less than a third of osteoporotic vertebral fractures (OVFs) come to clinical attention. This is due to a variety of reasons including inadequate understanding of the clinical triggers necessary to refer high risk individuals for spinal radiographs.... Read More about Addition of symptoms to traditional risk factors improves prediction of those at high risk of vertebral fractures: Results of the Vfrac study.

Long-term clinical and socio-economic outcomes following wrist fracture: A systematic review and meta-analysis (2021)
Journal Article

Purpose: To summarise and appraise evidence on the prognosis and long-term clinical and socio-economic outcomes following wrist fracture among adults aged 50 years and over. Methods: Five databases (MEDLINE, EMBASE, AMED, CINAHL-P and PsycINFO) we... Read More about Long-term clinical and socio-economic outcomes following wrist fracture: A systematic review and meta-analysis.

Fragility fractures and prescriptions of medications for osteoporosis in patients with polymyalgia rheumatica: results from the PMR Cohort Study (2021)
Journal Article

OBJECTIVES: PMR is a common indication for long-term glucocorticoid treatment, leading to an increased risk of osteoporosis and fragility fractures. Guidelines recommend calcium and vitamin D for all patients, in addition to anti-resorptive agents fo... Read More about Fragility fractures and prescriptions of medications for osteoporosis in patients with polymyalgia rheumatica: results from the PMR Cohort Study.

Addressing Conflicts of Interest in Health and Medicine: Current Evidence and Implications for Patient Decision Aid Development (2021)
Journal Article

BACKGROUND: More stringent policies for addressing conflicts of interest have been implemented around the world in recent years. Considering the value of revisiting conflict of interest quality standards set by the International Patient Decision Aid... Read More about Addressing Conflicts of Interest in Health and Medicine: Current Evidence and Implications for Patient Decision Aid Development.

Barriers and facilitators to the implementation of osteoarthritis management programmes in primary or community care settings: a systematic review and qualitative framework synthesis protocol. (2021)
Journal Article

Despite consistent international guidelines for osteoarthritis (OA) management, evidence-based treatments are underutilised. OA management programmes (OAMPs) are being implemented internationally to address this evidence-practice gap. An OAMP is defi... Read More about Barriers and facilitators to the implementation of osteoarthritis management programmes in primary or community care settings: a systematic review and qualitative framework synthesis protocol..

ACCEPTABILITY OF BISPHOSPHONATE TREATMENT REGIMENS FOR OSTEOPOROSIS: A QUALITATIVE SYSTEMATIC REVIEW (2021)
Presentation / Conference

Objective: To investigate the acceptability of different bisphosphonates treatment regimens for osteoporosis among patients and clinicians. Methods: A systematic review of qualitative research exploring patients’ and clinicians’ views of the accep... Read More about ACCEPTABILITY OF BISPHOSPHONATE TREATMENT REGIMENS FOR OSTEOPOROSIS: A QUALITATIVE SYSTEMATIC REVIEW.

Improving uptake of Fracture Prevention drug treatments: a protocol for Development of a consultation intervention (iFraP-D) (2021)
Journal Article

INTRODUCTION: Prevention of fragility fractures, a source of significant economic and personal burden, is hindered by poor uptake of fracture prevention medicines. Enhancing communication of scientific evidence and elicitation of patient medication-r... Read More about Improving uptake of Fracture Prevention drug treatments: a protocol for Development of a consultation intervention (iFraP-D).

PREVALENCE OF FRAGILITY FRACTURES AND MEDICATION PRESCRIPTION FOR OSTEOPOROSIS IN PATIENTS WITH POLYMYALGIA RHEUMATICA: RESULTS FROM THE PMR COHORT STUDY (2021)
Journal Article

Background/Aims Polymyalgia rheumatica (PMR) is one of the commonest indications for long term glucocorticoid (GC) use, leading to an increased risk of osteoporosis and fragility fractures. Clinical guidelines recommend prescribing medication includ... Read More about PREVALENCE OF FRAGILITY FRACTURES AND MEDICATION PRESCRIPTION FOR OSTEOPOROSIS IN PATIENTS WITH POLYMYALGIA RHEUMATICA: RESULTS FROM THE PMR COHORT STUDY.

Developing a model Fracture Liaison Service consultation with patients, carers and clinicians: a Delphi survey to inform content of the iFraP complex consultation intervention. (2021)
Journal Article

Fracture Liaison Services are recommended to deliver best practice in secondary fracture prevention. This modified Delphi survey, as part of the iFraP (Improving uptake of Fracture Prevention drug Treatments) study, provides consensus regarding tasks... Read More about Developing a model Fracture Liaison Service consultation with patients, carers and clinicians: a Delphi survey to inform content of the iFraP complex consultation intervention..

HIT (Hip Injection Trial) Advice and Exercise Leaflet (2021)
Book

Advice and exercises recommended for hip osteoarthritis. This leaflet is divided into 2 parts: The first section includes advice for day to day activities. The second section includes exercises. These are split into easy, medium and harder exercises.

Evaluation of quality and readability of online patient information on osteoporosis and osteoporosis drug treatment and recommendations for improvement (2021)
Journal Article

Purpose: Identify commonly accessed patient information resources about osteoporosis and osteoporosis drug treatment, appraise the quality and make recommendations for improvement. Methods: Patient information resources were purposively sampled and t... Read More about Evaluation of quality and readability of online patient information on osteoporosis and osteoporosis drug treatment and recommendations for improvement.

Experience of implementing and delivering group consultations in UK general practice: a qualitative study (2021)
Journal Article

BACKGROUND: Group consultations are a relatively new concept in UK primary care and are a suggested solution to current workload pressures in general practice. Little is known about the experience of implementing and delivering this approach from sta... Read More about Experience of implementing and delivering group consultations in UK general practice: a qualitative study.

Acceptability of bisphosphonates among patients, clinicians and managers: a systematic review and framework synthesis (2020)
Journal Article

OBJECTIVE: To explore the acceptability of different bisphosphonate regimens for the treatment of osteoporosis among patients, clinicians and managers, payers and academics. DESIGN: A systematic review of primary qualitative studies. Seven databases... Read More about Acceptability of bisphosphonates among patients, clinicians and managers: a systematic review and framework synthesis.

Understanding the uptake of a clinical innovation for osteoarthritis in primary care: a qualitative study of knowledge mobilisation using the i-PARIHS framework. (2020)
Journal Article

BACKGROUND: Osteoarthritis is a leading cause of pain and disability worldwide. Despite research supporting best practice, evidence-based guidelines are often not followed. Little is known about the implementation of non-surgical models of care in ro... Read More about Understanding the uptake of a clinical innovation for osteoarthritis in primary care: a qualitative study of knowledge mobilisation using the i-PARIHS framework..

A Primary Care Audit of Fracture Risk Management in Patients with a History of Chronic Pancreatitis (2020)
Presentation / Conference

Objective: To establish whether patients with a history of chronic pancreatitis have had appropriate fracture risk assessment. Methods: This audit was undertaken in a research ready, teaching practice with a list size of 11,377 on 18 November 2019... Read More about A Primary Care Audit of Fracture Risk Management in Patients with a History of Chronic Pancreatitis.

TARGETING COMMUNICATION IN THE CLINICIAN-PATIENT CONSULTATION TO IMPROVE UPTAKE OF FRACTURE PREVENTION TREATMENTS: EARLY FINDINGS FROM THE IFRAP STUDY (2020)
Presentation / Conference

iFraP is a 5-year study to design and test an intervention including a computerised decision aid, to use in the consultation, to promote informed decision making and informed adherence of osteoporosis drugs. Early findings from the iFraP study will b... Read More about TARGETING COMMUNICATION IN THE CLINICIAN-PATIENT CONSULTATION TO IMPROVE UPTAKE OF FRACTURE PREVENTION TREATMENTS: EARLY FINDINGS FROM THE IFRAP STUDY.

RECOMMENDATIONS TO IMPROVE QUALITY OF PATIENT INFORMATION MATERIALS IN OSTEOPOROSIS: RESULTS FROM A QUALITATIVE STUDY AND STAKEHOLDER CONSULTATION (2020)
Presentation / Conference

Objective: To identify inaccuracies, and contradictory statements in webbased patient information relating to osteoporosis and to produce recommendations for improvements. Methods: Nine commonly accessed patient information websites were selected f... Read More about RECOMMENDATIONS TO IMPROVE QUALITY OF PATIENT INFORMATION MATERIALS IN OSTEOPOROSIS: RESULTS FROM A QUALITATIVE STUDY AND STAKEHOLDER CONSULTATION.

Quality and effectiveness of osteoporosis treatment decision aids: a systematic review and environmental scan (2020)
Journal Article

Decision aids (DAs) are evidence-based tools that support shared decision-making (SDM) implementation in practice; this study aimed to identify existing osteoporosis DAs and assess their quality and efficacy; and to gain feedback from a patient advis... Read More about Quality and effectiveness of osteoporosis treatment decision aids: a systematic review and environmental scan.

IMPROVING COMMUNICATION OF FRACTURE RISK GLOBALLY: INSIGHTS FROM INTERVIEWS WITH PATIENTS. THE RISKCOMMUNICATION STUDY OR RICO STUDY (2020)
Presentation / Conference

Objective: Lack of or low quality communication between patient and healthcare provider may partially explain poor initiation and adherence to anti-osteoporosis treatment. In this study, we aimed to gain insights into patients’ understanding and pref... Read More about IMPROVING COMMUNICATION OF FRACTURE RISK GLOBALLY: INSIGHTS FROM INTERVIEWS WITH PATIENTS. THE RISKCOMMUNICATION STUDY OR RICO STUDY.

Qualitative findings from the Hip Injection Trial (HIT): experiences of living with hip osteoarthritis and receiving trial treatments (2020)
Journal Article

Background The HIT trial compared ultrasound-guided intra-articular hip injection (USGI) of triamcinolone acetonide and 1% lidocaine hydrochloride combined with best current treatment (BCT) with (i) BCT alone and (ii) an USGI of 1% lidocaine only co... Read More about Qualitative findings from the Hip Injection Trial (HIT): experiences of living with hip osteoarthritis and receiving trial treatments.

The hip injection trial (HIT) nested qualitative study: experiences of living with hip Osteoarthritis and receiving trial treatments. (2020)
Journal Article

Purpose: Evidence about the effectiveness of intra-articular corticosteroid injection for hip osteoarthritis (OA) is limited. The HIT trial compared ultrasound-guided intra-articular hip injection (USGI) of triamcinolone acetonide and 1% lidocaine hy... Read More about The hip injection trial (HIT) nested qualitative study: experiences of living with hip Osteoarthritis and receiving trial treatments..

O04 Clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injection for hip OA: a randomised controlled trial (HIT) (2020)
Presentation / Conference

Background Evidence of the effectiveness of intra-articular corticosteroid injection for hip osteoarthritis (OA) is limited. The HIT trial compared the clinical and cost-effectiveness of an ultrasound-guided intra-articular hip injection (USGI) of 4... Read More about O04 Clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injection for hip OA: a randomised controlled trial (HIT).

EXPERIENCES OF DELIVERING A NURSE-LED FRACTURE RISK ASSESSMENT FOR PATIENTS WITH INFLAMMATORY RHEUMATOLOGICAL CONDITIONS IN PRIMARY CARE (2020)
Presentation / Conference

Background The INCLUDE (INtegrating and improving Care for patients with infLammatory rheUmatological DisordErs in the community) pilot trial aimed to evaluate the feasibility and acceptability of a nurse-delivered review in primary care for people... Read More about EXPERIENCES OF DELIVERING A NURSE-LED FRACTURE RISK ASSESSMENT FOR PATIENTS WITH INFLAMMATORY RHEUMATOLOGICAL CONDITIONS IN PRIMARY CARE.

P193 Experiences of delivering a nurse-led fracture risk assessment for patients with inflammatory rheumatological conditions in primary care (2020)
Journal Article

Background The INCLUDE (INtegrating and improving Care for patients with infLammatory rheUmatological DisordErs in the community) pilot trial aimed to evaluate the feasibility and acceptability of a nurse-delivered review in primary care for people... Read More about P193 Experiences of delivering a nurse-led fracture risk assessment for patients with inflammatory rheumatological conditions in primary care.

Factors influencing the implementation of evidence-based guidelines for osteoarthritis in primary care: A systematic review and thematic synthesis. (2020)
Journal Article

INTRODUCTION: Implementation of evidence-based health guidelines in primary care is challenging. This systematic review aimed to synthesize qualitative evidence that investigates the factors influencing the implementation of evidence-based guidelines... Read More about Factors influencing the implementation of evidence-based guidelines for osteoarthritis in primary care: A systematic review and thematic synthesis..

Relative prevalence and distribution of knee, hand and foot symptomatic osteoarthritis subtypes in an English population (2020)
Journal Article

In this brief report, we used data from a series of three related cohorts on pain and osteoarthritis (OA) of the knee, hand and foot, which were conducted in North Staffordshire, England. We used a common approach for sampling, data collection and co... Read More about Relative prevalence and distribution of knee, hand and foot symptomatic osteoarthritis subtypes in an English population.

Research priorities for the management of broken bones of the upper limb in people over 50: a UK priority setting partnership with the James Lind Alliance (2019)
Journal Article

OBJECTIVE: To determine research priorities for the management of broken bones of the upper limb in people over 50, which represent the shared priorities of patients, their families, carers and healthcare professionals. DESIGN/SETTING: A national (UK... Read More about Research priorities for the management of broken bones of the upper limb in people over 50: a UK priority setting partnership with the James Lind Alliance.

Clinical Effectiveness of Ultrasound-guided Intra-articular Corticosteroid and Local Anaesthetic Injections for Hip Osteoarthritis: A Randomised Controlled Trial (HIT) (2019)
Presentation / Conference

Background/Purpose: Evidence of the effectiveness of intra-articular corticosteroid injection for hip osteoarthritis (OA) is limited and conflicting. The HIT trial compared the clinical effectiveness of an ultrasound-guided intra-articular hip inject... Read More about Clinical Effectiveness of Ultrasound-guided Intra-articular Corticosteroid and Local Anaesthetic Injections for Hip Osteoarthritis: A Randomised Controlled Trial (HIT).

"If It Was Unicorn Dust I'd Have It Again." Patient Experiences of Hip Osteoarthritis and Treatments in the Hip Injection Trial (2019)
Conference Proceeding

Background/Purpose: Evidence of the effectiveness of intra-articular corticosteroid injection for hip osteoarthritis (OA) is limited and conflicting. The HIT trial compared the clinical effectiveness of an ultrasound-guided intra-articular hip inject... Read More about "If It Was Unicorn Dust I'd Have It Again." Patient Experiences of Hip Osteoarthritis and Treatments in the Hip Injection Trial.

Return of the symptom? (2019)
Journal Article

Identifying women and men at risk of fragility fractures, who can benefit from prevention strategies such as bisphosphonate therapy, is an important topic for clinical and population epidemiology.

E059 Development of a nurse-led integrated care review based in primary care to identify and improve the management of co-morbidities in patients with inflammatory rheumatological conditions: the INCLUDE study (2019)
Journal Article

Background: People with inflammatory rheumatological conditions (IRCs) are at an increased risk of common comorbidities such as cardiovascular disease (CVD), osteoporosis, anxiety and depression. These are often not recognised or treated and can lead... Read More about E059 Development of a nurse-led integrated care review based in primary care to identify and improve the management of co-morbidities in patients with inflammatory rheumatological conditions: the INCLUDE study.

An observational cohort study to produce and evaluate an improved tool to screen older women with back pain for osteoporotic vertebral fractures (Vfrac): Study protocol (2019)
Journal Article

The aim of this study is to produce an easy to use checklist for general practitioners to complete whenever a woman aged over 65years with back pain seeks healthcare. This checklist will produce a binary output to determine if the patient should have... Read More about An observational cohort study to produce and evaluate an improved tool to screen older women with back pain for osteoporotic vertebral fractures (Vfrac): Study protocol.

Expressed information needs of patients with osteoporosis and/or fragility fractures: a systematic review (2018)
Journal Article

This systematic review identified patients have unmet information needs about the nature of osteoporosis, medication, self-management and follow-up. Clinician knowledge and attitudes appear to be of key importance in determining whether these needs a... Read More about Expressed information needs of patients with osteoporosis and/or fragility fractures: a systematic review.

DOES SMOKING CESSATION ADVICE WORK IN THE CONTEXT OF FRACTURE LIAISON SERVICE? RESULTS FROM A SERVICE AUDIT (2018)
Presentation / Conference

Background: Smoking is an important risk factor for fracture as it suppresses osteoblastic activity. Patients at high risk of fracture should be given smoking cessation advice as part of a package of lifestyle management/advice. Previous research in... Read More about DOES SMOKING CESSATION ADVICE WORK IN THE CONTEXT OF FRACTURE LIAISON SERVICE? RESULTS FROM A SERVICE AUDIT.

THE IMPLEMENTATION OF A VERTEBRAL FRACTURE ASSESSMENT PROTOCOL TO IMPROVE THE MANAGEMENT OF PATIENTS ATTENDING FOR ROUTINE DUAL ENERGY X-RAY ABSORPTIOMETRY (2018)
Presentation / Conference

Background: Vertebral fractures are the most common osteoporotic fracture in patients over the age of 60 and are associated with reduced quality of life, chronic pain and premature death. They are often undiagnosed and may occur in patients who have... Read More about THE IMPLEMENTATION OF A VERTEBRAL FRACTURE ASSESSMENT PROTOCOL TO IMPROVE THE MANAGEMENT OF PATIENTS ATTENDING FOR ROUTINE DUAL ENERGY X-RAY ABSORPTIOMETRY.

A randomised controlled trial of the clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injections: the hip injection trial (HIT) protocol (2018)
Journal Article

BACKGROUND: Evidence on the effectiveness of intra-articular corticosteroid injection for hip osteoarthritis is limited and conflicting. The primary objective of the Hip Injection Trial (HIT) is to compare pain intensity over 6 months, in people with... Read More about A randomised controlled trial of the clinical and cost-effectiveness of ultrasound-guided intra-articular corticosteroid and local anaesthetic injections: the hip injection trial (HIT) protocol.

Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials (2018)
Journal Article

Background Osteoarthritis (OA) is the most common long-term condition managed in UK general practice. However, care is suboptimal despite evidence that primary care and community-based interventions can reduce OA pain and disability. Objectives Th... Read More about Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials.

Risk of fragility fracture among patients with late-onset psoriasis: a United Kingdom population-based study (2018)
Journal Article

This study aimed to examine fracture risk in patients with late-onset psoriasis. A cohort study was conducted using primary care records from the Clinical Practice Research Datalink. Psoriasis patients had a 10% increased risk of fracture compared to... Read More about Risk of fragility fracture among patients with late-onset psoriasis: a United Kingdom population-based study.

EULAR recommendations for the health professional’s approach to pain management in inflammatory arthritis and osteoarthritis (2018)
Journal Article

Pain is the predominant symptom for people with inflammatory arthritis (IA) and osteoarthritis (OA) mandating the development of evidence-based recommendations for the health professional’s approach to pain management. A multidisciplinary task force... Read More about EULAR recommendations for the health professional’s approach to pain management in inflammatory arthritis and osteoarthritis.

Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study (2018)
Journal Article

Background Glucocorticoids are associated with increased fracture risk and are the mainstay of treatment in polymyalgia rheumatica (PMR) and giant cell arteritis (GCA). However, fracture risk in these conditions has not been previously quantified. T... Read More about Risk of fracture among patients with polymyalgia rheumatica and giant cell arteritis: a population-based study.

Patterns of routine primary care for osteoarthritis in the UK: a cross-sectional electronic health records study (2017)
Journal Article

Abstract Objective To determine common patterns of recorded primary care for osteoarthritis (OA), and patient and provider characteristics associated with the quality of recorded care. Design An observational study nested within a cluster-randomi... Read More about Patterns of routine primary care for osteoarthritis in the UK: a cross-sectional electronic health records study.

Exploring the Added Value of Video-Stimulated Recall in Researching the Primary Care Doctor-Patient Consultation: A Process Evaluation (2017)
Journal Article

Background: Video-stimulated recall (VSR) is a method whereby researchers show research participants a video of their own behavior to prompt and enhance their recall and interpretation after the event, for example, in a postconsultation interview. T... Read More about Exploring the Added Value of Video-Stimulated Recall in Researching the Primary Care Doctor-Patient Consultation: A Process Evaluation.

Implementing core NICE guidelines for osteoarthritis in primary care with a model consultation (MOSAICS): A cluster randomised controlled trial (2017)
Journal Article

Objective To determine the effectiveness of a model osteoarthritis consultation, compared with usual care, on physical function and uptake of National Institute for Health and Care Excellence (NICE) osteoarthritis recommendations, in adults =45 year... Read More about Implementing core NICE guidelines for osteoarthritis in primary care with a model consultation (MOSAICS): A cluster randomised controlled trial.

Incident acute pseudogout and prior bisphosphonate use: matched case-control study in the UK-Clinical Practice Research Datalink (2017)
Journal Article

Oral bisphosphonates are the most commonly used drugs to treat postmenopausal osteoporosis. Acute pseudogout is anecdotally reported to occur following bisphosphonate initiation but empirical data are lacking. We investigated whether treatment with o... Read More about Incident acute pseudogout and prior bisphosphonate use: matched case-control study in the UK-Clinical Practice Research Datalink.

Getting back to the dissecting room: an evaluation of an innovative course in musculoskeletal anatomy for UK-based rheumatology training (2017)
Journal Article

Background The rheumatologist relies heavily on clinical skills to diagnose diverse conditions, something that is correlated with one's knowledge of clinical anatomy. More recently, rheumatology has offered further career flexibility with opportunit... Read More about Getting back to the dissecting room: an evaluation of an innovative course in musculoskeletal anatomy for UK-based rheumatology training.

Incidence and medical management of bisphosphonate-associated atypical femoral fractures in a major trauma centre: a retrospective observational study (2017)
Journal Article

BACKGROUND: Atypical femoral fractures (AFFs) are rare events associated with increased duration of bisphosphonate exposure. Recommended management of AFFs include cessation of bisphosphonates and imaging of the contralateral femur. The aims of this... Read More about Incidence and medical management of bisphosphonate-associated atypical femoral fractures in a major trauma centre: a retrospective observational study.

The Identity Crisis of Osteoarthritis in General Practice: A Qualitative Study Using Video-Stimulated Recall (2015)
Journal Article

PURPOSE Patients and doctors report marked disenchantment with primary care consultation experiences relating to osteoarthritis. This study aimed to observe and analyze interactions between general practitioners (GPs) and patients presenting with ost... Read More about The Identity Crisis of Osteoarthritis in General Practice: A Qualitative Study Using Video-Stimulated Recall.

The relative importance of perceived doctor's attitude on the decision to consult for symptomatic osteoarthritis: a choice-based conjoint analysis study. (2015)
Journal Article

Objectives Some patients spend years with painful osteoarthritis without consulting for it, including times when they are experiencing persistent severe pain and disability. Beliefs about osteoarthritis and what primary care has to offer may influenc... Read More about The relative importance of perceived doctor's attitude on the decision to consult for symptomatic osteoarthritis: a choice-based conjoint analysis study..

Bisphosphonates and Risk of Acute Pseudogout: A Case-Control Study in the Clinical Practice Research Datalink (CPRD). (2014)
Presentation / Conference

Background/Purpose: Acute pseudogout is the most dramatic clinical manifestation of calcium pyrophosphate crystal deposition (CPPD). CPPD is most commonly sporadic and age-related but can rarely occur secondary to metabolic diseases or a familial tra... Read More about Bisphosphonates and Risk of Acute Pseudogout: A Case-Control Study in the Clinical Practice Research Datalink (CPRD)..

Getting under the skin of the primary care consultation using video stimulated recall: a systematic review (2014)
Journal Article

BACKGROUND: Video stimulated recall (VSR) is a method of enhancing participants' accounts of the consultation using a video recording of the event to encourage and prompt recall in a post consultation interview. VSR is used in education and education... Read More about Getting under the skin of the primary care consultation using video stimulated recall: a systematic review.

Comparison of patient experiences of the osteoarthritis consultation with GP attitudes and beliefs to OA: a narrative review (2014)
Journal Article

BACKGROUND: Osteoarthritis (OA) is a common cause of disability and consultation with a GP. However, little is known about what currently happens when patients with OA consult their GP. This review aims to compare existing literature reporting patien... Read More about Comparison of patient experiences of the osteoarthritis consultation with GP attitudes and beliefs to OA: a narrative review.

What influences patients with Osteoarthritis to consult their GP about their symptoms? A narrative review (2013)
Journal Article

BACKGROUND: Osteoarthritis (OA) is a common cause of disability and consultation with a GP. However research suggests the majority of sufferers choose not to consult their GP regarding their symptoms. Understanding the reasons for consulting is centr... Read More about What influences patients with Osteoarthritis to consult their GP about their symptoms? A narrative review.

P060 Living with rheumatoid arthritis during the coronavirus pandemic: a longitudinal interview study
Presentation / Conference

Background/Aims The COVID-19 pandemic placed patients with rheumatoid arthritis (RA) at increased risk of poor outcomes as a result of their condition, compounded by use of immunosuppressant medication, and higher prevalence of comorbidities. As a co... Read More about P060 Living with rheumatoid arthritis during the coronavirus pandemic: a longitudinal interview study.