Oksana Kehoe's Outputs (2)

Extracellular vesicle bioactivity and potential clinical utility is determined by mesenchymal stromal cell clonal subtype (2024)
Working Paper
Ioannou, S., G Kay, A., P Stone, A., Rand, E., Elberfeld, S., Bolton, W., …Genever, P. Extracellular vesicle bioactivity and potential clinical utility is determined by mesenchymal stromal cell clonal subtype

Mesenchymal stromal cells (MSCs) are a promising source of therapeutic extracellular vesicles (EVs), however it is not clear how heterogeneity within a non-clonal MSC population will affect the collective EV pool. Here we used immortalised clonal MSC... Read More about Extracellular vesicle bioactivity and potential clinical utility is determined by mesenchymal stromal cell clonal subtype.

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches (2024)
Journal Article
Kehoe, O., Welsh, J. A., Goberdhan, D. C., O'Driscoll, L., Buzas, E. I., Blenkiron, C., …Witwer, K. W. (2024). Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches. Journal of Extracellular Vesicles, 13(2), Article e12404. https://doi.org/10.1002/jev2.12404

Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of origin and change the functions and phenotypes of other cells. These features indicate strong biomarker and therapeutic potential and have
generated b... Read More about Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches.