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Divya Chari's Outputs (4)

Electrophysiological assessment of primary cortical neurons genetically engineered using iron oxide nanoparticles (2017)
Journal Article
Evans, M., Shakli, A., Jenkins, S., & Chari, D. (2017). Electrophysiological assessment of primary cortical neurons genetically engineered using iron oxide nanoparticles. Nano Research, 2881-2890. https://doi.org/10.1007/s12274-017-1496-4

The development of safe technologies to genetically modify neurons is of great interest in regenerative neurology, for both translational and basic science applications. Such approaches have conventionally been heavily reliant on viral transduction m... Read More about Electrophysiological assessment of primary cortical neurons genetically engineered using iron oxide nanoparticles.

A fusion of minicircle DNA and nanoparticle delivery technologies facilitates therapeutic genetic engineering of autologous canine olfactory mucosal cells. (2017)
Journal Article
Delaney, A., Adams, C., Fernandes, A., Al-Shakli, A., Sen, J., Carwardine, D., …Chari, D. (2017). A fusion of minicircle DNA and nanoparticle delivery technologies facilitates therapeutic genetic engineering of autologous canine olfactory mucosal cells. Nanoscale, 9, 8560--8566. https://doi.org/10.1039/c7nr00811b

Olfactory ensheathing cells (OECs) promote axonal regeneration and improve locomotor function when transplanted into the injured spinal cord. A recent clinical trial demonstrated improved motor function in domestic dogs with spinal injury following a... Read More about A fusion of minicircle DNA and nanoparticle delivery technologies facilitates therapeutic genetic engineering of autologous canine olfactory mucosal cells..