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Outputs (29)

The Relationship Between Obesity and Patient-Reported Outcome Measures in People with Polymyalgia Rheumatica (2024)
Journal Article
Scott, I., Bajpai, R., Hider, S., Helliwell, T., Mallen, C., & Muller, S. (in press). The Relationship Between Obesity and Patient-Reported Outcome Measures in People with Polymyalgia Rheumatica. Rheumatology Advances in Practice, Article rkae081. https://doi.org/10.1093/rap/rkae081

Objective To examine the association between obesity and patient-reported outcomes measures (PROMs) in a primary care-based cohort of people with polymyalgia rheumatica (PMR). Methods The PMR Cohort Study recruited people with incident PMR from... Read More about The Relationship Between Obesity and Patient-Reported Outcome Measures in People with Polymyalgia Rheumatica.

Management of Refractory Disease and Persistent Symptoms in Inflammatory Arthritis: Qualitative Framework analysis of interviews with patients and healthcare professionals (2024)
Journal Article
Chaplin, H., Simpson, C., Wilkins, K., Meehan, J., Ng, N., Galloway, J., …Norton, S. (2024). Management of Refractory Disease and Persistent Symptoms in Inflammatory Arthritis: Qualitative Framework analysis of interviews with patients and healthcare professionals. Rheumatology Advances in Practice, 8(3), Article rkae076. https://doi.org/10.1093/rap/rkae076

Objectives: This study aims to explore patients’ and clinicians’ experiences of managing and living with refractory disease (RD) and persistent physical and emotional symptoms (PPES) in patients with Rheumatoid Arthritis or Polyarticular Juvenile Idi... Read More about Management of Refractory Disease and Persistent Symptoms in Inflammatory Arthritis: Qualitative Framework analysis of interviews with patients and healthcare professionals.

E041 Feasibility and acceptability of electronic patient reported outcome measures in the routine care of people with inflammatory arthritis: Haywood Arthritis Portal study (2024)
Presentation / Conference
Cox, N., Kettle, C., Wang, H., Dutta, S., Packham, J., Galloway, J., …Scott, I. C. (2024, April). E041 Feasibility and acceptability of electronic patient reported outcome measures in the routine care of people with inflammatory arthritis: Haywood Arthritis Portal study. Poster presented at British Society for Rheumatology Annual Conference 2024

Background/Aims Electronic patient-reported outcome measures (ePROMs) assessing disease activity, function, pain, and quality of life can facilitate innovative inflammatory arthritis (IA) care, such as automating patient-initiated follow-up. This mix... Read More about E041 Feasibility and acceptability of electronic patient reported outcome measures in the routine care of people with inflammatory arthritis: Haywood Arthritis Portal study.

P045 Google Internet Searches Related to Inflammatory Arthritis: an Observational Study Using Google Trends Data (2024)
Presentation / Conference
Akthar, M., Mason, K. J., & Scott, I. C. (2024, April). P045 Google Internet Searches Related to Inflammatory Arthritis: an Observational Study Using Google Trends Data. Poster presented at British Society for Rheumatology Annual Conference 2024

Background/Aims Inflammatory arthritis (IA) care involves a paradox. Rheumatologists focus on reducing disease activity through treat-to-target (T2T). But surveys/qualitative studies show patients’ main concern is pain. As these studies include a min... Read More about P045 Google Internet Searches Related to Inflammatory Arthritis: an Observational Study Using Google Trends Data.

Analgesic Prescribing in Patients with Inflammatory Arthritis in England: Observational Studies in the Clinical Practice Research Datalink (2023)
Journal Article
Scott, I. C., Jordan, K. P., Twohig, H., Whittle, R., Muller, S., Hider, S. L., …Bailey, J. (2023). Analgesic Prescribing in Patients with Inflammatory Arthritis in England: Observational Studies in the Clinical Practice Research Datalink. Rheumatology, Article kead463. https://doi.org/10.1093/rheumatology/kead463

Despite little evidence that analgesics are effective in inflammatory arthritis (IA), studies report substantial opioid prescribing. The extent this applies to other analgesics is uncertain. We undertook a comprehensive evaluation of analgesic prescr... Read More about Analgesic Prescribing in Patients with Inflammatory Arthritis in England: Observational Studies in the Clinical Practice Research Datalink.

Heterogeneity of treatment responses in rheumatoid arthritis using group based trajectory models: secondary analysis of clinical trial data (2023)
Journal Article
Ibrahim, F., Scott, I. C., Scott, D. L., & Ayis, S. A. (in press). Heterogeneity of treatment responses in rheumatoid arthritis using group based trajectory models: secondary analysis of clinical trial data. BMC Rheumatology, 7(1), Article 33. https://doi.org/10.1186/s41927-023-00348-5

Background Traditionally rheumatoid arthritis (RA) trials classify patients as responders and non-responders; they ignore the potential range of treatment responses. Group Based Trajectory Models (GBTMs) provide a more refined approach. They identif... Read More about Heterogeneity of treatment responses in rheumatoid arthritis using group based trajectory models: secondary analysis of clinical trial data.

The relationship between pain and depression and anxiety in patients with inflammatory arthritis: a systematic review protocol (2023)
Journal Article
Cox, N., Hawarden, A., Bajpai, R., Farooq, S., Twohig, H., Muller, S., & Scott, I. C. (2024). The relationship between pain and depression and anxiety in patients with inflammatory arthritis: a systematic review protocol. Rheumatology International, 44, 435–440. https://doi.org/10.1007/s00296-023-05450-y

Pain is a major challenge for patients with inflammatory arthritis (IA). Depression and anxiety are common comorbidities in IA, associating with worse outcomes. How they relate to pain is uncertain, with existing systematic reviews (a) mainly conside... Read More about The relationship between pain and depression and anxiety in patients with inflammatory arthritis: a systematic review protocol.

P098 Changes in Analgesic Prescribing in Patients with Inflammatory Arthritis in England: An Observational Study in CPRD Aurum (2023)
Presentation / Conference
C Scott, I., Whittle, R., Bailey, J., Twohig, H., L Hider, S., D Mallen, C., …P Jordan, K. (2023, April). P098 Changes in Analgesic Prescribing in Patients with Inflammatory Arthritis in England: An Observational Study in CPRD Aurum. Poster presented at British Society for Rheumatology Annual Conference 2023, Manchester Central Convention Complex, Manchester, UK

Background/Aims Pain is a common symptom experienced by patients with inflammatory arthritis (IA). Emerging data indicate IA pain treatment focuses on prescribing analgesics despite an absence of evidence for long-term efficacy. Delivering optimal,... Read More about P098 Changes in Analgesic Prescribing in Patients with Inflammatory Arthritis in England: An Observational Study in CPRD Aurum.

P100 The Impact of Intensive Management on Pain Intensity in Patients with Rheumatoid Arthritis and Psoriatic Arthritis: Secondary Analysis of Three Clinical Trials (2023)
Presentation / Conference
Scott, I. C., Scott, D. L., & Ibrahim, F. (2023, April). P100 The Impact of Intensive Management on Pain Intensity in Patients with Rheumatoid Arthritis and Psoriatic Arthritis: Secondary Analysis of Three Clinical Trials. Poster presented at British Society for Rheumatology Annual Conference 2023, Manchester Central Convention Complex, Manchester, UK

Digital exclusion as a potential cause of inequalities in access to care: a survey in people with inflammatory rheumatic diseases (2023)
Journal Article
Hider, S., Muller, S., Gray, L., Manning, F., Heining, D., Menon, A., …Paskins, Z. (2023). Digital exclusion as a potential cause of inequalities in access to care: a survey in people with inflammatory rheumatic diseases. Rheumatology Advances in Practice, 7(1), https://doi.org/10.1093/rap/rkac109

Objectives: COVID-19 led to rapid uptake of digital healthcare. We sought to examine digital access, health and digital literacy, and impact on confidence and satisfaction with remote consultations in people with inflammatory rheumatic diseases (IRDs... Read More about Digital exclusion as a potential cause of inequalities in access to care: a survey in people with inflammatory rheumatic diseases.

The impact of the COVID-19 pandemic and stringent social distancing measures on health-related quality of life and COVID-19 infection rates in patients with rheumatic disease: a longitudinal analysis through the pandemic (2022)
Journal Article
Cox, N., R Raizada, S., Barkham, N., Venkatachalam, S., Sheeran, T. P., Adizie, T., …Bateman, J. (2022). The impact of the COVID-19 pandemic and stringent social distancing measures on health-related quality of life and COVID-19 infection rates in patients with rheumatic disease: a longitudinal analysis through the pandemic. Rheumatology Advances in Practice, 7(1), Article rkad009. https://doi.org/10.1093/rap/rkad009

Objective The aim was to evaluate the impact of the coronavirus disease 2019 (COVID-19) pandemic and stringent social isolation measures on patients with rheumatic disease (RD) from the beginning of the pandemic (April 2020). Methods In this UK-based... Read More about The impact of the COVID-19 pandemic and stringent social distancing measures on health-related quality of life and COVID-19 infection rates in patients with rheumatic disease: a longitudinal analysis through the pandemic.

Rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis epidemiology in England from 2004 to 2020: An observational study using primary care electronic health record data (2022)
Journal Article
Scott, I. C., Whittle, R., Bailey, J., Twohig, H., Hider, S., Mallen, C., …Jordan, K. (2022). Rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis epidemiology in England from 2004 to 2020: An observational study using primary care electronic health record data. The Lancet Regional Health Europe, 23, Article 100519. https://doi.org/10.1016/j.lanepe.2022.100519

Background: Contemporary data on rheumatoid arthritis (RA), psoriatic arthritis (PsA) and axial spondyloarthritis (SpA) epidemiology in England are lacking. This knowledge is crucial to planning healthcare services. We updated algorithms defining pat... Read More about Rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis epidemiology in England from 2004 to 2020: An observational study using primary care electronic health record data.

P059 Acceptability of remote consulting during COVID-19 among patients with two common long-term musculoskeletal conditions: findings from three qualitative studies and recommendations for practice (2022)
Journal Article
Paskins, Z., Bullock, L., Manning, F., Bishop, S., Campbell, P., Cottrell, E., …Ryan, S. (2022). P059 Acceptability of remote consulting during COVID-19 among patients with two common long-term musculoskeletal conditions: findings from three qualitative studies and recommendations for practice. Rheumatology, 61(S1), https://doi.org/10.1093/rheumatology/keac133.058

Abstract Background/Aims The COVID-19 pandemic led to the widespread adoption of remote consultations. Whilst remote consultations offer many potential advantages to patients and healthcare services, they are unlikely to be suitable for all. Guidanc... Read More about P059 Acceptability of remote consulting during COVID-19 among patients with two common long-term musculoskeletal conditions: findings from three qualitative studies and recommendations for practice.

P183 Establishing the epidemiology of rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis in England using primary care electronic health record data (2022)
Journal Article
Scott, I. C., Whittle, R., Bailey, J., Twohig, H., Hider, S., Mallen, C., …Jordan, K. (2022). P183 Establishing the epidemiology of rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis in England using primary care electronic health record data. Rheumatology, 61(S1), https://doi.org/10.1093/rheumatology/keac133.182

Abstract Background/Aims The substantial personal and socioeconomic costs associated with rheumatoid arthritis (RA), psoriatic arthritis (PsA), and axial spondyloarthritis (SpA) make understanding their epidemiology crucial. The Clinical Practice Re... Read More about P183 Establishing the epidemiology of rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis in England using primary care electronic health record data.

Acceptability of, and preferences for, remote consulting during COVID-19 among older patients with two common long-term musculoskeletal conditions: findings from three qualitative studies and recommendations for practice (2022)
Journal Article
Paskins, Z., Bullock, L., Manning, F., Bishop, S., Campbell, P., Cottrell, E., …Ryan, S. (2022). Acceptability of, and preferences for, remote consulting during COVID-19 among older patients with two common long-term musculoskeletal conditions: findings from three qualitative studies and recommendations for practice. BMC Musculoskeletal Disorders, 23, Article 312. https://doi.org/10.1186/s12891-022-05273-1

Background Guidance for choosing face-to-face vs remote consultations (RCs) encourages clinicians to consider patient preferences, however, little is known about acceptability of, and preferences for RCs, particularly amongst patients with musculoske... Read More about Acceptability of, and preferences for, remote consulting during COVID-19 among older patients with two common long-term musculoskeletal conditions: findings from three qualitative studies and recommendations for practice.

Analgesic prescribing in patients with inflammatory arthritis in England: an observational study using electronic healthcare record data (2021)
Journal Article
Scott, I. C., Bailey, J., White, C. R., Mallen, C., & Muller, S. (2022). Analgesic prescribing in patients with inflammatory arthritis in England: an observational study using electronic healthcare record data. Rheumatology, 61(8), 3201–3211. https://doi.org/10.1093/rheumatology/keab870

OBJECTIVES: International data suggest inflammatory arthritis (IA) pain management frequently involves opioid prescribing, despite little evidence of efficacy, and potential harms. We evaluated analgesia prescribing in English National Health Service... Read More about Analgesic prescribing in patients with inflammatory arthritis in England: an observational study using electronic healthcare record data.

Validation of the Musculoskeletal Health Questionnaire (MSK-HQ) in Primary Care Patients with Musculoskeletal Pain (2020)
Journal Article
Scott, I. C., McCray, G., Lancaster, G., Foster, N. E., & Hill, J. C. (2020). Validation of the Musculoskeletal Health Questionnaire (MSK-HQ) in Primary Care Patients with Musculoskeletal Pain. Seminars in Arthritis and Rheumatism, 50(5), 813-820. https://doi.org/10.1016/j.semarthrit.2020.06.022

Objective To evaluate the responsiveness, and concurrent validity of the Musculoskeletal Health Questionnaire (MSK-HQ) in UK primary care patients with common musculoskeletal (MSK) pain presentations. Methods A secondary analysis of a primary ca... Read More about Validation of the Musculoskeletal Health Questionnaire (MSK-HQ) in Primary Care Patients with Musculoskeletal Pain.

THE RELATIONSHIP BETWEEN OBESITY AND OUTCOMES IN PATIENTS WITH POLYMYALGIA RHEUMATICA (2020)
Journal Article
Helliwell, T., Mallen, C. D., Scott, I. C., Bajpai, R., Muller, S., & Hider, S. L. (2020). THE RELATIONSHIP BETWEEN OBESITY AND OUTCOMES IN PATIENTS WITH POLYMYALGIA RHEUMATICA. Rheumatology, 59, 18-18. https://doi.org/10.1093/RHEUMATOLOGY/KEAA110.037

Background Obesity predisposes to a pro-inflammatory state. Studies have reported worse clinical outcomes in patients with inflammatory arthritis who are obese. The relationship between obesity and outcomes in patients with polymyalgia rheumatica (P... Read More about THE RELATIONSHIP BETWEEN OBESITY AND OUTCOMES IN PATIENTS WITH POLYMYALGIA RHEUMATICA.

The relationship between obesity and outcomes in patients with polymyalgia rheumatica (2020)
Presentation / Conference
Scott, I. C., Bajpai, R., Mallen, C., Muller, S., Helliwell, T., & Hider, S. (2020, April). The relationship between obesity and outcomes in patients with polymyalgia rheumatica. Presented at British Society for Rheumatology Annual Conference 2020, Scottish Event Campus (SEC), Scotland, UK

Background Obesity predisposes to a pro-inflammatory state. Studies have reported worse clinical outcomes in patients with inflammatory arthritis who are obese. The relationship between obesity and outcomes in patients with polymyalgia rheumatica (P... Read More about The relationship between obesity and outcomes in patients with polymyalgia rheumatica.

P197 Analgesic prescribing in patients with inflammatory arthritis in the NHS (2020)
Journal Article
Scott, I. C., Bailey, J., White, C., Mallen, C. D., & Muller, S. (2020). P197 Analgesic prescribing in patients with inflammatory arthritis in the NHS. Rheumatology, 59(Supplement_2), https://doi.org/10.1093/rheumatology/keaa111.192

Background There is little evidence analgesics improve pain in inflammatory arthritis (IA), and substantial evidence they have significant harms. Excepting NSAIDs in ankylosing spondylitis (AS), their long-term use is not recommended in guidelines.... Read More about P197 Analgesic prescribing in patients with inflammatory arthritis in the NHS.

Correction to: The association between anxiety and disease activity and quality of life in rheumatoid arthritis: a systematic review and meta-analysis. (2020)
Journal Article
Machin, A. R., Babatunde, O., Haththotuwa, R., Scott, I., Blagojevic-Bucknall, M., Corp, N., …Hider, S. L. (2020). Correction to: The association between anxiety and disease activity and quality of life in rheumatoid arthritis: a systematic review and meta-analysis. Clinical Rheumatology, 39(4), 1373–1375. https://doi.org/10.1007/s10067-020-04954-3

The authors of the published original version of the above article wanted to correct the below text in the Abstract section.

The association between gravidity, parity and the risk of developing rheumatoid arthritis: A systematic review and meta-analysis. (2019)
Journal Article
Chen, W. M., Subesinghe, S., Muller, S., Hider, S. L., Mallen, C. D., & Scott, I. C. (2019). The association between gravidity, parity and the risk of developing rheumatoid arthritis: A systematic review and meta-analysis. Seminars in Arthritis and Rheumatism, 50(2), 252-260. https://doi.org/10.1016/j.semarthrit.2019.09.003

OBJECTIVE: To establish if gravidity and parity associate with the development of rheumatoid arthritis (RA), and to establish if this effect is influenced by the time elapsed since pregnancy/childbirth, the number of pregnancies/childbirths, and sero... Read More about The association between gravidity, parity and the risk of developing rheumatoid arthritis: A systematic review and meta-analysis..

Symptoms associated with inflammatory arthritis are common in the primary care population: results from the Joint Symptoms Survey (2019)
Journal Article
Hider, S. L., Muller, S., Helliwell, T., Prior, J. A., Scott, I., Lawton, S. A., …Mallen, C. D. (2019). Symptoms associated with inflammatory arthritis are common in the primary care population: results from the Joint Symptoms Survey. Rheumatology, 58(11), 2009-2014. https://doi.org/10.1093/rheumatology/kez184

Objectives: To describe the prevalence of self-reported inflammatory joint symptoms, such as joint pain, stiffness and swelling in UK primary care patients consulting for both musculoskeletal (MSK) and non-musculoskeletal (non-MSK) complaints. Met... Read More about Symptoms associated with inflammatory arthritis are common in the primary care population: results from the Joint Symptoms Survey.

The extra-articular impacts of rheumatoid arthritis: moving towards holistic care (2018)
Journal Article
Scott, I., Machin, A., Mallen, C., & Hider, S. (2018). The extra-articular impacts of rheumatoid arthritis: moving towards holistic care. BMC Rheumatology, 2, Article 32. https://doi.org/10.1186/s41927-018-0039-2

Although treat-to-target has revolutionised the outcomes of patients with rheumatoid arthritis (RA) there is emerging evidence that attaining the target of remission is insufficient to normalise patients' quality of life, and ameliorate the extra-art... Read More about The extra-articular impacts of rheumatoid arthritis: moving towards holistic care.

Impact of intensive treatment and remission on health-related quality of life in early and established rheumatoid arthritis. (2016)
Journal Article
Scott, I. C., Ibrahim, F., Lewis, C. M., Scott, D. L., & Strand, V. (2016). Impact of intensive treatment and remission on health-related quality of life in early and established rheumatoid arthritis. RMD Open, 2(2), https://doi.org/10.1136/rmdopen-2016-000270

Objectives To establish if using intensive treatment to reduce synovitis and attain remission in active rheumatoid arthritis (RA) improves all aspects of health-related quality of life (HRQoL). Methods A secondary analysis of two randomised clinic... Read More about Impact of intensive treatment and remission on health-related quality of life in early and established rheumatoid arthritis..

A randomised trial evaluating anakinra in early active rheumatoid arthritis. (2016)
Journal Article
Scott, I. C., Ibrahim, F., Simpson, G., Kowalczyk, A., White-Alao, B., Hassell, A., …Scott, D. L. (2016). A randomised trial evaluating anakinra in early active rheumatoid arthritis. Clinical and Experimental Rheumatology, 34(1), 88-93

OBJECTIVES: The effectiveness of anakinra (interleukin-1 receptor antagonist) in early rheumatoid arthritis (RA) is unknown. We evaluated the efficacy of anakinra (combined with methotrexate) in a randomised clinical trial of early active RA patient... Read More about A randomised trial evaluating anakinra in early active rheumatoid arthritis..

Changing clinical patterns in rheumatoid arthritis management over two decades: sequential observational studies. (2016)
Journal Article
Mian, A. N., Ibrahim, F., Scott, I. C., Bahadur, S., Filkova, M., Pollard, L., …Galloway, J. (2016). Changing clinical patterns in rheumatoid arthritis management over two decades: sequential observational studies. BMC Musculoskeletal Disorders, 17, Article 44. https://doi.org/10.1186/s12891-016-0897-y

Background Rheumatoid arthritis (RA) treatment paradigms have shifted over the last two decades. There has been increasing emphasis on combination disease modifying anti-rheumatic drug (DMARD) therapy, newer biologic therapies have become available... Read More about Changing clinical patterns in rheumatoid arthritis management over two decades: sequential observational studies..