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Outputs (38)

Automating incidence and prevalence analysis in open cohorts (2024)
Journal Article
Cockburn, N., Hammond, B., Gani, I., Cusworth, S., Acharya, A., Gokhale, K., …Chandan, J. S. (in press). Automating incidence and prevalence analysis in open cohorts. BMC medical research methodology, 24, Article 144. https://doi.org/10.1186/s12874-024-02266-7

Motivation Data is increasingly used for improvement and research in public health, especially administrative data such as that collected in electronic health records. Patients enter and exit these typically open-cohort datasets non-uniformly; this... Read More about Automating incidence and prevalence analysis in open cohorts.

Endocervical crypt involvement by high-grade cervical intraepithelial neoplasia and its association with high-grade histopathological recurrence after cervical excision in women with negative excision margins: a systematic review and meta-analysis (2023)
Journal Article
Papoutsis, D., Underwood, M., Parry-Smith, W., & Tzavara, C. (2024). Endocervical crypt involvement by high-grade cervical intraepithelial neoplasia and its association with high-grade histopathological recurrence after cervical excision in women with negative excision margins: a systematic review and meta-analysis. Archives of Gynecology and Obstetrics, 309, 939–948. https://doi.org/10.1007/s00404-023-07242-y

Background There is a growing body of evidence suggesting that endocervical crypt involvement by high-grade cervical intraepithelial neoplasia (CIN) may represent a risk factor for disease recurrence after cervical treatment. Objectives To provi... Read More about Endocervical crypt involvement by high-grade cervical intraepithelial neoplasia and its association with high-grade histopathological recurrence after cervical excision in women with negative excision margins: a systematic review and meta-analysis.

The association between menstrual cycle characteristics and cardiometabolic outcomes in later life: a retrospective matched cohort study of 704,743 women from the UK. (2023)
Journal Article
Okoth, K., Parry-Smith, W., Thomas, G. N., Nirantharakumar, K., & Adderley, N. J. (2023). The association between menstrual cycle characteristics and cardiometabolic outcomes in later life: a retrospective matched cohort study of 704,743 women from the UK. BMC Medicine, 21, Article 104. https://doi.org/10.1186/s12916-023-02794-x

Outcomes of gynecologic cancer surgery during the COVID-19 pandemic: an international, multicenter, prospective CovidSurg-Gynecologic Oncology Cancer study. (2022)
Journal Article
Fotopoulou, C., Khan, T., Bracinik, J., Glasbey, J., Abu-Rustum, N., Chiva, L., …Parry-Smith, W. (2022). Outcomes of gynecologic cancer surgery during the COVID-19 pandemic: an international, multicenter, prospective CovidSurg-Gynecologic Oncology Cancer study. American Journal of Obstetrics and Gynecology, 227(5), 735.e1-735.e25. https://doi.org/10.1016/j.ajog.2022.06.052

Worth the paper it's written on- A cross-sectional study of Medical Certificate of Stillbirth accuracy in the UK (2022)
Journal Article
Rimmer, M. P., Henderson, I., Parry-Smith, W., Raglan, O., Tamblyn, J., Heazell, A. E. P., …working group, T. U. N. (2023). Worth the paper it's written on- A cross-sectional study of Medical Certificate of Stillbirth accuracy in the UK. International Journal of Epidemiology, 52(1), 295–308. https://doi.org/10.1093/ije/dyac100

Background The Medical Certificate of Stillbirth (MCS) records data about a baby’s death after 24 weeks of gestation but before birth. Major errors that could alter interpretation of the MCS were widespread in two UK-based regional studies. Metho... Read More about Worth the paper it's written on- A cross-sectional study of Medical Certificate of Stillbirth accuracy in the UK.

Effectiveness of a web-based virtual journal club to promote medical education (Web-Ed): protocol of a multicentre pragmatic randomised trial (2022)
Journal Article
Rimmer, M., Elfaki, N., Dunlop, C., Coleburt, D., Cowan, N., Raglan, O., …Al Wattar, B. (2022). Effectiveness of a web-based virtual journal club to promote medical education (Web-Ed): protocol of a multicentre pragmatic randomised trial. BMJ Open, 12(6), Article e058610. https://doi.org/10.1136/bmjopen-2021-058610

Introduction A journal club (JC) is a commonly used medical educational tool. Videoconferencing technology can facilitate the delivery of JCs, however, there remains no evidence on the role of web-based virtual JCs in promoting the acquisition and re... Read More about Effectiveness of a web-based virtual journal club to promote medical education (Web-Ed): protocol of a multicentre pragmatic randomised trial.

Healing pattern of the cervical stroma following cold coagulation treatment for cervical intraepithelial neoplasia: A case report (2022)
Journal Article
Papoutsis, D., Williams, J., Underwood, M., & Parry-Smith, W. (2022). Healing pattern of the cervical stroma following cold coagulation treatment for cervical intraepithelial neoplasia: A case report. Oncology Letters, 23, Article 81. https://doi.org/10.3892/ol.2022.13201

Cold coagulation of the cervix for cervical intraepithelial neoplasia (CIN), when compared with cervical excision, has previously demonstrated comparable cure rates and a reduction in the rate of spontaneous preterm birth. In the present report the h... Read More about Healing pattern of the cervical stroma following cold coagulation treatment for cervical intraepithelial neoplasia: A case report.

Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study (2021)
Journal Article
Collaborative*, C., & Parry-Smith, W. (2021). Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study. Lancet Oncology, 22(11), 1507-1517. https://doi.org/10.1016/S1470-2045%2821%2900493-9

Background Surgery is the main modality of cure for solid cancers and was prioritised to continue during COVID-19 outbreaks. This study aimed to identify immediate areas for system strengthening by comparing the delivery of elective cancer surgery d... Read More about Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study.

SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study. (2021)
Journal Article
Collaborative, C., Collaborative, G., & Parry-Smith, W. (2022). SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study. Anaesthesia, 77(1), 28-39. https://doi.org/10.1111/anae.15563

SARS-CoV-2 has been associated with an increased rate of venous thromboembolism in critically ill patients. Since surgical patients are already at higher risk of venous thromboembolism than general populations, this study aimed to determine if patien... Read More about SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study..

Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study. (2021)
Journal Article
Collaborative, C., Collaborative, G., & Parry-Smith, W. (2021). Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study. Anaesthesia, 76(11), 1454-1464. https://doi.org/10.1111/anae.15560

We aimed to determine the impact of pre-operative isolation on postoperative pulmonary complications after elective surgery during the global SARS-CoV-2 pandemic. We performed an international prospective cohort study including patients undergoing el... Read More about Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study..

The patient with abnormal cervical cytology (2021)
Book Chapter
Underwood, M., & Parry-Smith, W. (2021). The patient with abnormal cervical cytology. In Assisted Reproduction Techniques: Challenges and Management Options (123-126). Wiley. https://doi.org/10.1002/9781119622215.ch19

This chapter includes clinical cases, background, evidence-based practical management options, preventive measures, key-point summaries of abnormal cervical cytology and answers to questions patients ask. Cervical screening programs around the world... Read More about The patient with abnormal cervical cytology.

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study (2021)
Journal Article
Collaborative, C., Collaborative, G., & Parry-Smith, W. (2021). SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study. British Journal of Surgery, 108(9), 1056-1063. https://doi.org/10.1093/bjs/znab101

Background Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods The primary outcome was the number needed to vaccinate (NNV... Read More about SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.

Postpartum haemorrhage and risk of mental ill health: A population-based longitudinal study using linked primary and secondary care databases (2021)
Journal Article
Parry-Smith, W., Okoth, K., Subramanian, A., Gokhale, K. M., Chandan, J. S., Humpston, C., …Šumilo, D. (2021). Postpartum haemorrhage and risk of mental ill health: A population-based longitudinal study using linked primary and secondary care databases. Journal of Psychiatric Research, 137, 419-425. https://doi.org/10.1016/j.jpsychires.2021.03.022

The FAST‐M complex intervention for the detection and management of maternal sepsis in low‐resource settings: a multi‐site evaluation (2021)
Journal Article
Cheshire, J., Jones, L., Munthali, L., Kamphinga, C., Liyaya, H., Phiri, T., …Lissauer, D. (2021). The FAST‐M complex intervention for the detection and management of maternal sepsis in low‐resource settings: a multi‐site evaluation. BJOG: An International Journal of Obstetrics and Gynaecology, 128(8), 1324–1333. https://doi.org/10.1111/1471-0528.16658

Objective To evaluate whether the implementation of the FAST-M complex intervention was feasible and improved the recognition and management of maternal sepsis in a low-resource setting. Design A before-and-after design. Setting Fifteen gove... Read More about The FAST‐M complex intervention for the detection and management of maternal sepsis in low‐resource settings: a multi‐site evaluation.

Escalation triggers and expected responses in obstetric early warning systems used in UK consultant-led maternity units (2020)
Journal Article
Cheshire, J., Lissauer, D., Parry-Smith, W., Tobias, A., Smith, G. B., Isaacs, R., & Hundley, V. (in press). Escalation triggers and expected responses in obstetric early warning systems used in UK consultant-led maternity units. Resuscitation Plus, 5, Article 100060. https://doi.org/10.1016/j.resplu.2020.100060

Background The use of obstetric early warning systems (OEWS) are recommended as an adjunct to reduce maternal morbidity and mortality. The aim of this review was to document the variation in OEWS trigger thresholds and the quality of information inc... Read More about Escalation triggers and expected responses in obstetric early warning systems used in UK consultant-led maternity units.

Expansile Endocervical Crypt Involvement by CIN2 – 3 as a Risk Factor for High Grade Cytology Recurrence After Cold Coagulation Cervical Treatment (2020)
Journal Article
Papoutsis, D., Underwood, M., Williams, J., Parry-Smith, W., & Panikkar, J. (in press). Expansile Endocervical Crypt Involvement by CIN2 – 3 as a Risk Factor for High Grade Cytology Recurrence After Cold Coagulation Cervical Treatment. Geburtshilfe und Frauenheilkunde, 80(9), 941-948. https://doi.org/10.1055/a-1202-2157

Introduction To determine whether expansile endocervical crypt involvement (ECI) on pretreatment cervical punch biopsies is a risk factor for high grade cytology recurrence in women following cold coagulation for cervical intraepithelial neoplasia (C... Read More about Expansile Endocervical Crypt Involvement by CIN2 – 3 as a Risk Factor for High Grade Cytology Recurrence After Cold Coagulation Cervical Treatment.

Babies in occiput posterior position are significantly more likely to require an emergency cesarean birth compared with babies in occiput transverse position in the second stage of labor: A prospective observational study. (2019)
Journal Article
Tempest, N., Lane, S., Hapangama, D., Collaborative in Obstetrics, U. A. R. T., (UK-ARCOG), G., & Parry-Smith, W. (2020). Babies in occiput posterior position are significantly more likely to require an emergency cesarean birth compared with babies in occiput transverse position in the second stage of labor: A prospective observational study. Acta obstetricia et gynecologica Scandinavica, 99(4), 537-545. https://doi.org/10.1111/aogs.13765

Introduction Malposition complicates 2-13% of births at delivery, leading to increased obstetric interventions (cesarean section and instrumental delivery) and higher rates of adverse fetal and maternal outcomes. Limited data are available regarding... Read More about Babies in occiput posterior position are significantly more likely to require an emergency cesarean birth compared with babies in occiput transverse position in the second stage of labor: A prospective observational study..

Evaluating the value of intrapartum fetal scalp blood sampling to predict adverse neonatal outcomes: A UK multicentre observational study. (2019)
Journal Article
Al Wattar, B. H., Lakhiani, A., Sacco, A., Siddharth, A., Bain, A., Calvia, A., …study group, A. (2019). Evaluating the value of intrapartum fetal scalp blood sampling to predict adverse neonatal outcomes: A UK multicentre observational study. European Journal of Obstetrics and Gynecology and Reproductive Biology, 240, 62-67. https://doi.org/10.1016/j.ejogrb.2019.06.012

Objective To evaluate the value of fetal scalp blood sampling (FBS) as an adjunct test to cardiotocography, to predict adverse neonatal outcomes. Study design A multicentre service evaluation observational study in forty-four maternity units in... Read More about Evaluating the value of intrapartum fetal scalp blood sampling to predict adverse neonatal outcomes: A UK multicentre observational study..

Early and late pregnancy outcomes in women treated with cold-coagulation versus LLETZ cervical treatment for cervical intraepithelial neoplasia; a retrospective cohort study (2018)
Journal Article
Papoutsis, D., Underwood, M., Parry-Smith, W., & Panikkar, J. (2018). Early and late pregnancy outcomes in women treated with cold-coagulation versus LLETZ cervical treatment for cervical intraepithelial neoplasia; a retrospective cohort study. Archives of Gynecology and Obstetrics, 297(4), 1015-1025. https://doi.org/10.1007/s00404-018-4704-x

Purpose To compare the pregnancy outcomes between women who were treated with cold-coagulation versus large loop excision of the transformation zone (LLETZ) for cervical intraepithelial neoplasia. Methods This was a retrospective cohort study of... Read More about Early and late pregnancy outcomes in women treated with cold-coagulation versus LLETZ cervical treatment for cervical intraepithelial neoplasia; a retrospective cohort study.

First‐line uterotonics for treating postpartum haemorrhage: a systematic review and network meta‐analysis (2017)
Journal Article
Parry Smith, W. R., Gallos, I. D., Williams, H. M., Widmer, M., Angolkar, M., Tobias, A., …Coomarasamy, A. (2017). First‐line uterotonics for treating postpartum haemorrhage: a systematic review and network meta‐analysis. Cochrane Database of Systematic Reviews, https://doi.org/10.1002/14651858.CD012754

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: Primary To assess the relative effectiveness and produce a clinically meaningful hierarchy of first‐line uterotonic drugs for the treatment of postpartum ha... Read More about First‐line uterotonics for treating postpartum haemorrhage: a systematic review and network meta‐analysis.

Does CIN2 Have the Same Aggressive Potential As CIN3? A Secondary Analysis of High-Grade Cytology Recurrence in Women Treated with Cold-Coagulation Cervical Treatment (2017)
Journal Article
Papoutsis, D., Underwood, M., Parry-Smith, W., & Panikkar, J. (2017). Does CIN2 Have the Same Aggressive Potential As CIN3? A Secondary Analysis of High-Grade Cytology Recurrence in Women Treated with Cold-Coagulation Cervical Treatment. Geburtshilfe und Frauenheilkunde, 77(03), 284-289. https://doi.org/10.1055/s-0042-119993

Introduction To determine whether women with CIN2 versus CIN3 on pretreatment cervical punch biopsy have less high-grade cytology recurrence following cold-coagulation cervical treatment. Materials and Methods This was a retrospective study of wom... Read More about Does CIN2 Have the Same Aggressive Potential As CIN3? A Secondary Analysis of High-Grade Cytology Recurrence in Women Treated with Cold-Coagulation Cervical Treatment.

RCOG/AAGBI global partnerships map: an innovative project to increase awareness of and collaboration between global healthcare partnerships (2017)
Presentation / Conference
Sobhy, S., Lightly, K., Shewry, E., Letchworth, P., McCauley, M., Merriel, A., …Stephens, M. (2017, March). RCOG/AAGBI global partnerships map: an innovative project to increase awareness of and collaboration between global healthcare partnerships. Poster presented at RCOG World Congress 2017, CTICC Cape Town, South Africa

Comparison of cure rates in women treated with cold-coagulation versus LLETZ cervical treatment for CIN2-3 on pretreatment cervical punch biopsies: a retrospective cohort study (2017)
Journal Article
Papoutsis, D., Underwood, M., Parry-Smith, W., & Panikkar, J. (2017). Comparison of cure rates in women treated with cold-coagulation versus LLETZ cervical treatment for CIN2-3 on pretreatment cervical punch biopsies: a retrospective cohort study. Archives of Gynecology and Obstetrics, 295, 979-986. https://doi.org/10.1007/s00404-017-4306-z

Purpose To compare the cure rates between women who were treated with cold-coagulation versus large loop excision of the transformation zone (LLETZ) for cervical intraepithelial neoplasia grade 2 (CIN2) or 3 (CIN3) on pretreatment cervical punch bio... Read More about Comparison of cure rates in women treated with cold-coagulation versus LLETZ cervical treatment for CIN2-3 on pretreatment cervical punch biopsies: a retrospective cohort study.

Training on Kielland’s forceps: A survey of trainees’ opinions (2017)
Journal Article
Al Wattar, B., Mahmud, A., Janjua, A., Parry-Smith, W., & Ismail, K. (in press). Training on Kielland’s forceps: A survey of trainees’ opinions. Journal of Obstetrics and Gynaecology, 37(3), 280-283. https://doi.org/10.1080/01443615.2016.1196476

We conducted a cross-sectional survey including specialist trainees in obstetrics and gynaecology in the Health Education West Midlands region, UK, to capture their views and assess training opportunities on the use of Kielland’s forceps. Half of the... Read More about Training on Kielland’s forceps: A survey of trainees’ opinions.

Management of obstetric postpartum hemorrhage: A national service evaluation of current practice in the UK (2017)
Journal Article
Al Wattar, B., Tamblyn, J., Parry-Smith, W., Prior, M., & Van Der Nelson, H. (2017). Management of obstetric postpartum hemorrhage: A national service evaluation of current practice in the UK. Risk Management and Healthcare Policy, 10, 1-6. https://doi.org/10.2147/RMHP.S121737

Background: Postpartum hemorrhage (PPH) continues to be one of the major causes of maternal mortality and morbidity in obstetrics. Variations in practice often lead to adverse maternity outcomes following PPH. Our objective was to assess the current... Read More about Management of obstetric postpartum hemorrhage: A national service evaluation of current practice in the UK.

Consultants as victims of bullying and undermining: A survey of Royal College of Obstetricians and Gynaecologists consultant experiences (2016)
Journal Article
Shabazz, T., Parry-Smith, W., Oates, S., Henderson, S., & Mountfield, J. (2016). Consultants as victims of bullying and undermining: A survey of Royal College of Obstetricians and Gynaecologists consultant experiences. BMJ Open, 6, Article e011462. https://doi.org/10.1136/bmjopen-2016-011462

Objective To explore incidents of bullying and undermining among obstetrics and gynaecology (O&G) consultants in the UK, to add another dimension to previous research and assist in providing a more holistic understanding of the problem in medicine.... Read More about Consultants as victims of bullying and undermining: A survey of Royal College of Obstetricians and Gynaecologists consultant experiences.

Bullying and undermining: a threat to both patient care and medical personnel wellbeing? A cross sectional survey of the Undergraduates, trainees and consultants in Obstetrics and Gynaecology in the West Midlands (2015)
Journal Article
Parry-Smith, W., Morse, L., Sutherland, A., Horrocks, P., & O’Mahony, F. (2015). Bullying and undermining: a threat to both patient care and medical personnel wellbeing? A cross sectional survey of the Undergraduates, trainees and consultants in Obstetrics and Gynaecology in the West Midlands. MedEdPublish,

Risk factors for treatment failure following cold coagulation cervical treatment for CIN pathology: a cohort-based study (2015)
Journal Article
Papoutsis, D., Underwood, M., Parry-Smith, W., & Panikkar, J. (2015). Risk factors for treatment failure following cold coagulation cervical treatment for CIN pathology: a cohort-based study. Archives of Gynecology and Obstetrics, 292, 1329-1337. https://doi.org/10.1007/s00404-015-3761-7

Purpose To determine any risk factors for cytology recurrence in women after cold coagulation ablative treatment for cervical intraepithelial neoplasia (CIN). Methods This was a retrospective observational study of a cohort of women having had c... Read More about Risk factors for treatment failure following cold coagulation cervical treatment for CIN pathology: a cohort-based study.

Success Rate of cold coagulation for the treatment of cervical intraepithelial neoplasia: A retrospective analysis of a series of cases (2015)
Journal Article
Parry-Smith, W., Underwood, M., De Bellis-Ayres, S., Bangs, L., Redman, C., & Panikkar, J. (2015). Success Rate of cold coagulation for the treatment of cervical intraepithelial neoplasia: A retrospective analysis of a series of cases. Journal of Lower Genital Tract Disease, 19(1), 17-21. https://doi.org/10.1097/LGT.0000000000000031

Objective To establish the cure rate at 1 year of patients who have undergone cold coagulation for the treatment of cervical intraepithelial neoplasia (CIN). Design Retrospective review of data for all patients at Shrewsbury and Telford NHS Tr... Read More about Success Rate of cold coagulation for the treatment of cervical intraepithelial neoplasia: A retrospective analysis of a series of cases.

Intravascular leiomyomatosis: A case report and review of the literature (2014)
Journal Article
Simon, A., Parry-Smith, W., Redman, C., Kodampur, M., Todd, R., Satur, C., & Morgan, R. (2015). Intravascular leiomyomatosis: A case report and review of the literature. Journal of Obstetrics and Gynaecology, 35, 539-540. https://doi.org/10.3109/01443615.2014.978847

Intravascular leiomyomatosis (IVL) is a rare condition in which histologically benign smooth muscle neoplasms arising from the intrauterine vessels infiltrate and invade systemic veins, including the inferior vena cava (IVC) (CitationCho et al. 2011)... Read More about Intravascular leiomyomatosis: A case report and review of the literature.

Cytological follow-up after hysterectomy: Is vaginal vault cytology sampling a clinical governance problem? The University Hospital of North Staffordshire approach (2014)
Journal Article
Parry-Smith, W., Thorpe, D., Ogboro-Okor, L., Underwood, M., Ismaili, E., Kodampur, M., …Redman, C. (2015). Cytological follow-up after hysterectomy: Is vaginal vault cytology sampling a clinical governance problem? The University Hospital of North Staffordshire approach. Cytopathology, 26, 188-193

Objectives Vaginal vault cytology sampling following hysterectomy is recommended for specific indications in national guidelines. However, clinical governance issues surround compliance with guidance. Our first study objective was to quantify how ma... Read More about Cytological follow-up after hysterectomy: Is vaginal vault cytology sampling a clinical governance problem? The University Hospital of North Staffordshire approach.