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Outputs (30)

The value of an embedded qualitative study in a trial of a second antidepressant for people who had not responded to one antidepressant: understanding the perspectives of patients and general practitioners (2018)
Journal Article
Chew-Graham, C., Shepherd, T., Burroughs, H., Dixon, K., & Kessler, D. (2018). The value of an embedded qualitative study in a trial of a second antidepressant for people who had not responded to one antidepressant: understanding the perspectives of patients and general practitioners. BMC Family Practice, https://doi.org/10.1186/s12875-018-0877-4

BACKGROUND: Depression is the leading cause of disability worldwide, and is a major contributor to the overall global burden of disease. The number of prescriptions for antidepressants has risen dramatically in recent years yet up to 50% of patients... Read More about The value of an embedded qualitative study in a trial of a second antidepressant for people who had not responded to one antidepressant: understanding the perspectives of patients and general practitioners.

RCGP Research Paper of the Year 2017: of relevance to the General Practice Forward View? (2018)
Journal Article
Chew-Graham, C. (2018). RCGP Research Paper of the Year 2017: of relevance to the General Practice Forward View?. British Journal of General Practice, 68(676), 536-537. https://doi.org/10.3399/bjgp18X699641

The Research Paper of the Year (RPY), awarded by the Royal College of General Practitioners (RCGP), gives recognition to an individual or group of researchers who have undertaken and published an exceptional piece of research relating to general prac... Read More about RCGP Research Paper of the Year 2017: of relevance to the General Practice Forward View?.

How older adults self-manage distress - does the internet have a role? A qualitative study (2018)
Journal Article
Moult, A., Burroughs, H., Kingstone, T., & Chew-Graham, C. A. (2018). How older adults self-manage distress - does the internet have a role? A qualitative study. BMC Family Practice, 185 - ?. https://doi.org/10.1186/s12875-018-0874-7

BACKGROUND
Anxiety and depression are common in older adults, but often under-recognised by GPs. Rather than perceiving themselves as suffering from anxiety or depression, older adults are more likely to self-identify as experiencing low mood, stres... Read More about How older adults self-manage distress - does the internet have a role? A qualitative study.

The Elicitation and Management of Multiple Health Concerns in GP Consultations (2018)
Journal Article
Chew-Graham. (2018). The Elicitation and Management of Multiple Health Concerns in GP Consultations. Patient Education and Counseling, https://doi.org/10.1016/j.pec.2018.11.009

Objective
To describe the nature of patient concerns and to explore if, when and how they are addressed by GPs in the UK.

Methods
Detailed coding and descriptive analysis of 185 video recordings from the EPaC study (Elicitation of Patient Concer... Read More about The Elicitation and Management of Multiple Health Concerns in GP Consultations.

Combining mirtazapine with SSRIs or SNRIs for treatment-resistant depression: the MIR RCT. (2018)
Journal Article
Chew-Graham. (2018). Combining mirtazapine with SSRIs or SNRIs for treatment-resistant depression: the MIR RCT. Health Technology Assessment, 1 - 136. https://doi.org/10.3310/hta22630

BACKGROUND: Depression is usually managed in primary care and antidepressants are often the first-line treatment, but only half of those treated respond to a single antidepressant. OBJECTIVES: To investigate whether or not combining mirtazapine with... Read More about Combining mirtazapine with SSRIs or SNRIs for treatment-resistant depression: the MIR RCT..

Self-harm in a primary care cohort of older people: incidence, clinical management, and risk of suicide and other causes of death (2018)
Journal Article
Morgan, C., Webb, R. T., Carr, M. J., Kontopantelis, E., Chew-Graham, C. A., Kapur, N., & Ashcroft, D. M. (2018). Self-harm in a primary care cohort of older people: incidence, clinical management, and risk of suicide and other causes of death. The Lancet Psychiatry, 905-912. https://doi.org/10.1016/S2215-0366%2818%2930348-1

BACKGROUND: Self-harm is a major risk factor for suicide, with older adults (older than 65 years) having reportedly greater suicidal intent than any other age group. With the aging population rising and paucity of research focus in this age group, th... Read More about Self-harm in a primary care cohort of older people: incidence, clinical management, and risk of suicide and other causes of death.

Mirtazapine added to SSRIs or SNRIs for treatment resistant depression in primary care: phase III randomised placebo controlled trial (MIR) (2018)
Journal Article
Kessler, D. S., MacNeill, S. J., Tallon, D., Lewis, G., Peters, T. J., Hollingworth, W., …Wiles, N. J. (2018). Mirtazapine added to SSRIs or SNRIs for treatment resistant depression in primary care: phase III randomised placebo controlled trial (MIR). BMJ, k4218 - ?. https://doi.org/10.1136/bmj.k4218

OBJECTIVE: To investigate the effectiveness of combining mirtazapine with serotonin-noradrenaline reuptake inhibitor (SNRI) or selective serotonin reuptake inhibitor (SSRI) antidepressants for treatment resistant depression in primary care. DESIGN: T... Read More about Mirtazapine added to SSRIs or SNRIs for treatment resistant depression in primary care: phase III randomised placebo controlled trial (MIR).

MIRtazapine added to SSRIs or SNRIs for Treatment Resistant Depression in Primary Care: a placebo controlled randomised trial (MIR) (2018)
Journal Article
Chew-Graham. (2018). MIRtazapine added to SSRIs or SNRIs for Treatment Resistant Depression in Primary Care: a placebo controlled randomised trial (MIR). BMJ, https://doi.org/10.1136/bmj.k4218

Objective: To investigate the effectiveness of combining mirtazapine with Serotonin-Noradrenaline Reuptake Inhibitor (SNRI) or Selective Serotonin Reuptake Inhibitor (SSRI) antidepressants for patients in primary care who had not responded to an anti... Read More about MIRtazapine added to SSRIs or SNRIs for Treatment Resistant Depression in Primary Care: a placebo controlled randomised trial (MIR).

Association Between Physician Burnout and Patient Safety, Professionalism, and Patient Satisfaction: A Systematic Review and Meta-analysis. (2018)
Journal Article
Chew-Graham. (2018). Association Between Physician Burnout and Patient Safety, Professionalism, and Patient Satisfaction: A Systematic Review and Meta-analysis. JAMA Internal Medicine, 1317 - 1330. https://doi.org/10.1001/jamainternmed.2018.3713

Importance: Physician burnout has taken the form of an epidemic that may affect core domains of health care delivery, including patient safety, quality of care, and patient satisfaction. However, this evidence has not been systematically quantified.... Read More about Association Between Physician Burnout and Patient Safety, Professionalism, and Patient Satisfaction: A Systematic Review and Meta-analysis..