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Factors associated with change in health-related quality of life in people with gout: a 3-year prospective cohort study in primary care (2022)
Journal Article
Watson, L., Belcher, J., Nicholls, E., Chandratre, P., Blagojevic-Bucknall, M., Hider, S., Lawton, S. A., Mallen, C. D., Muller, S., Rome, K., & Roddy, E. (2022). Factors associated with change in health-related quality of life in people with gout: a 3-year prospective cohort study in primary care. Rheumatology, 62(8), 2748-2756. https://doi.org/10.1093/rheumatology/keac706

Objective To describe factors associated with change in health-related quality of life (HRQOL) in people living with gout in primary care. Methods In a UK prospective cohort study, adults with a diagnosis of gout registered with 20 general practices... Read More about Factors associated with change in health-related quality of life in people with gout: a 3-year prospective cohort study in primary care.

A Genome-Wide Association Analysis of 2,622,830 Individuals Reveals New Pathogenic Pathways in Gout (2022)
Presentation / Conference Contribution
Merriman, T., Matsuo, H., Takei, R., Leask, M., Topless, R., Shirai, Y., Li, Z., Cadzow, M., Reynolds, R., Saag, K., Fadason, T., O'Sullivan, J., Dalbeth, N., Stamp, L., Abhishek, A., Doherty, M., Roddy, E., Jacobsson, L., Kapetanovic, M., Andrès, M., …Major, T. (2022, November). A Genome-Wide Association Analysis of 2,622,830 Individuals Reveals New Pathogenic Pathways in Gout. Presented at ACR Convergence 2022

Background/Purpose: Genome-wide association studies (GWAS) in gout have been relatively small (≤13,179 people with gout) and have provided little insight into the progression from hyperuricemia to gout. We present a gout GWAS that includes 120,282 pe... Read More about A Genome-Wide Association Analysis of 2,622,830 Individuals Reveals New Pathogenic Pathways in Gout.

Treat-to-target urate-lowering therapy and hospitalisations for gout: results from a nationwide cohort study in England. (2022)
Journal Article
Roddy, E., Russell, M. D., Rutherford, A. I., Ellis, B., Norton, S., Douiri, A., Gulliford, M. C., Cope, A. P., & Galloway, J. B. (2023). Treat-to-target urate-lowering therapy and hospitalisations for gout: results from a nationwide cohort study in England. Rheumatology, 62(7), 2426-2434. https://doi.org/10.1093/rheumatology/keac638

Objective To investigate associations between treat-to-target urate-lowering therapy (ULT) and hospitalizations for gout. Methods Using linked Clinical Practice Research Datalink and NHS Digital Hospital Episode Statistics data, we described the inci... Read More about Treat-to-target urate-lowering therapy and hospitalisations for gout: results from a nationwide cohort study in England..

British Society for Rheumatology guideline on prescribing drugs in pregnancy and breastfeeding: immunomodulatory anti-rheumatic drugs and corticosteroids (2022)
Journal Article
Russell, M. D., Dey, M., Flint, J., Davie, P., Allen, A., Crossley, A., Frishman, M., Gayed, M., Hodson, K., Khamashta, M., Moore, L., Panchal, S., Piper, M., Reid, C., Saxby, K., Schreiber, K., Senvar, N., Tosounidou, S., van de Venne, M., Warburton, L., …Williams, E. (2022). British Society for Rheumatology guideline on prescribing drugs in pregnancy and breastfeeding: immunomodulatory anti-rheumatic drugs and corticosteroids. Rheumatology, 62(4), e48-e88. https://doi.org/10.1093/rheumatology/keac551

Association of Gout Polygenic Risk Score with Age at Disease Onset and Tophaceous Disease in European and Polynesian Men with Gout. (2022)
Journal Article
Roddy, E. (2022). Association of Gout Polygenic Risk Score with Age at Disease Onset and Tophaceous Disease in European and Polynesian Men with Gout. Arthritis and Rheumatology, 75(5), 816-825. https://doi.org/10.1002/art.42393

OBJECTIVE: To determine whether a gout polygenic risk score (PRS) associates with age at gout onset and tophaceous disease in European (EUR), East Polynesian (EP), and West Polynesian (WP) men/women with gout.

METHODS: A 19-variant gout PRS was p... Read More about Association of Gout Polygenic Risk Score with Age at Disease Onset and Tophaceous Disease in European and Polynesian Men with Gout..

A Genome-Wide Association Analysis of 2,622,830 Individuals Reveals New Pathogenic Pathways in Gout (2022)
Journal Article
Roddy. (2022). A Genome-Wide Association Analysis of 2,622,830 Individuals Reveals New Pathogenic Pathways in Gout. Arthritis and Rheumatology, 3338 - 3341

Background/Purpose: Genome-wide association studies (GWAS) in gout have been relatively small (=13,179 people with gout) and have provided little insight into the progression from hyperuricemia to gout. We present a gout GWAS that includes 120,282 pe... Read More about A Genome-Wide Association Analysis of 2,622,830 Individuals Reveals New Pathogenic Pathways in Gout.

Large variation in participant eligibility criteria used in plantar heel pain research studies - a systematic review. (2022)
Journal Article
Riel, H., Plinsinga, M. L., Delahunt, E., Jensen, M. B., Landorf, K. B., van Middelkoop, M., Roddy, E., Rathleff, M. S., Vicenzino, B., & Olesen, J. L. (2022). Large variation in participant eligibility criteria used in plantar heel pain research studies - a systematic review. Journal of Foot and Ankle Research, 15(1), Article 69. https://doi.org/10.1186/s13047-022-00573-0

INTRODUCTION: Variable eligibility criteria across studies on plantar heel pain may result in compromising the generalisability of meta-analyses when heterogeneity is not accounted for. We aimed to explore: (i) heterogeneity of participant eligibilit... Read More about Large variation in participant eligibility criteria used in plantar heel pain research studies - a systematic review..

Incidence and Progression of Hallux Valgus: A Prospective Cohort Study (2022)
Journal Article
Menz, H. B., Marshall, M., Thomas, M. J., Rathod‐Mistry, T., Peat, G. M., & Roddy, E. (2023). Incidence and Progression of Hallux Valgus: A Prospective Cohort Study. Arthritis Care and Research, 75(1), 166-173. https://doi.org/10.1002/acr.24754

OBJECTIVE: Hallux valgus is a common and disabling condition. The objective of this study was to identify factors associated with hallux valgus incidence and progression. METHODS: Participants were from a population-based prospective cohort study, th... Read More about Incidence and Progression of Hallux Valgus: A Prospective Cohort Study.