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TCT-148 An international analyses of 122,610 NSTEMI patients with 5 year outcomes: assessing the influence of age and comorbidities on invasively vs medically managed patients between 2004 and 2014. (2018)
Presentation / Conference
Protty, M., Al-zuhairi, K., Kinnaird, T., Mamas, M., Torp-Pedersen, C., Smith, D., & Freeman, P. (2018, September). TCT-148 An international analyses of 122,610 NSTEMI patients with 5 year outcomes: assessing the influence of age and comorbidities on invasively vs medically managed patients between 2004 and 2014. Poster presented at Thirtieth Annual Symposium Transcatheter Cardiovascular Therapeutics (TCT), San Diego, CA, USA

NSTEMI patients are at risk of death, reinfarction and ischaemia, a risk that increases as cardiovascular risk (GRACE) increases. However, data from UK national registries identifies at least 60,000 NSTEMI patients per year not receiving an invasive... Read More about TCT-148 An international analyses of 122,610 NSTEMI patients with 5 year outcomes: assessing the influence of age and comorbidities on invasively vs medically managed patients between 2004 and 2014..

Radial artery access and outcomes for left main stem PCI: an analysis of 19,482 cases from the British Cardiovascular Intervention Society national database (2018)
Presentation / Conference
Kinnaird, T., Anderson, R., Sirker, A., Ludman, P., de Belder, M., Oldroyd, K., …Mamas, M. (2018, September). Radial artery access and outcomes for left main stem PCI: an analysis of 19,482 cases from the British Cardiovascular Intervention Society national database. Presented at 13th Annual Symposium Transcatheter Cardiovascular Therapeutics (TCT)

Background
Although the predictors and outcomes of radial versus femoral access are well defined for unselected PCI procedures and certain sub-groups, there are few data for patients undergoing left main stem percutaneous coronary intervention (LMS-... Read More about Radial artery access and outcomes for left main stem PCI: an analysis of 19,482 cases from the British Cardiovascular Intervention Society national database.

TCT-766 Coronary perforation complicating percutaneous coronary intervention in patients presenting with an acute coronary syndrome: an analysis of 1,013 perforation cases from the British Cardiovascular Intervention Society database (2018)
Journal Article
Kinnaird, T., Calvert, P., Anderson, R., Sirker, A., de Belder, M., Ludman, P., …Mamas, M. (2018). TCT-766 Coronary perforation complicating percutaneous coronary intervention in patients presenting with an acute coronary syndrome: an analysis of 1,013 perforation cases from the British Cardiovascular Intervention Society database. Journal of the American College of Cardiology, 72(13), Article B306. https://doi.org/10.1016/j.jacc.2018.08.1994

Background
The evidence base for coronary perforation (CP) occurring during percutaneous coronary intervention in patients presenting with an acute coronary syndrome (ACS-PCI) is limited with the specific role of acute pharmacology in its clinical p... Read More about TCT-766 Coronary perforation complicating percutaneous coronary intervention in patients presenting with an acute coronary syndrome: an analysis of 1,013 perforation cases from the British Cardiovascular Intervention Society database.

Changes in Peri-procedural Bleeding Complications Following Percutaneous Coronary Intervention in The United Kingdom Between 2006-2013 (From the British Cardiovascular Interventional Society) (2018)
Journal Article
Mamas, M., Nolan, J., & Rashid, M. (2018). Changes in Peri-procedural Bleeding Complications Following Percutaneous Coronary Intervention in The United Kingdom Between 2006-2013 (From the British Cardiovascular Interventional Society). American Journal of Cardiology, 952-960. https://doi.org/10.1016/j.amjcard.2018.06.016

Major bleeding is a common complication following percutaneous coronary intervention (PCI), although little is known about how bleeding rates have changed over time and what has driven this. We analyzed all patients undergoing PCI in England and Wale... Read More about Changes in Peri-procedural Bleeding Complications Following Percutaneous Coronary Intervention in The United Kingdom Between 2006-2013 (From the British Cardiovascular Interventional Society).

Chronic kidney disease, worsening renal function and outcomes in a heart failure community setting: A UK national study (2018)
Journal Article
Mamas. (2018). Chronic kidney disease, worsening renal function and outcomes in a heart failure community setting: A UK national study. International Journal of Cardiology, 120 - 127. https://doi.org/10.1016/j.ijcard.2018.04.090

Background Routine heart failure (HF) monitoring and management is in the community but the natural course of worsening renal function (WRF) and its influence on HF prognosis is unknown. We investigated the influence of routinely monitored renal decl... Read More about Chronic kidney disease, worsening renal function and outcomes in a heart failure community setting: A UK national study.

A feasibility study of transaxillary TAVI with the lotus valve (2018)
Journal Article
Mamas. (2018). A feasibility study of transaxillary TAVI with the lotus valve. Catheterization and Cardiovascular Interventions, 542 -549. https://doi.org/10.1002/ccd.27409

Objectives
To assess the feasibility of axillary transcatheter aortic valve implantation (TAVI) using the Lotus valve.

Background
TAVI is used to treat patients with severe aortic stenosis, with transfemoral (TF) access being the safest and most... Read More about A feasibility study of transaxillary TAVI with the lotus valve.

5258Trends and outcomes of use of coronary angiography in management of non-ST-Elevation acute coronary syndromes (NSTEACS), a population based cohort study (2018)
Journal Article
Rashid, M., Potts, J., Kwok, C., Mohammed, M., Shoaib, A., Esnsor, J., …Mamas, M. (2018). 5258Trends and outcomes of use of coronary angiography in management of non-ST-Elevation acute coronary syndromes (NSTEACS), a population based cohort study. European Heart Journal, 39(suppl_1), https://doi.org/10.1093/eurheartj/ehy566.5258

Background: Non-ST-elevation acute coronary syndromes (NSTEACS) remains most vulnerable phenotype of acute myocardial infarction despite significant improvements in treatment and provision of guideline-recommended care. Coronary angiography (CA) is t... Read More about 5258Trends and outcomes of use of coronary angiography in management of non-ST-Elevation acute coronary syndromes (NSTEACS), a population based cohort study.

P6029Impact of elixhauser comorbidity score on the outcomes of transcatheter aortic valve replacement (2018)
Journal Article
Nagaraja, V., Generaeux, P., Cohen, M., Suh, W., Alasnag, M., Potts, J., …Research Group, K. C. (2018). P6029Impact of elixhauser comorbidity score on the outcomes of transcatheter aortic valve replacement. European Heart Journal, 39(suppl_1), https://doi.org/10.1093/eurheartj/ehy566.p6029

Background: Patients undergoing transcatheter aortic valve replacement (TAVR) are often multi-morbid. Whilst the impact of individual comorbid conditions on clinical outcomes following TAVR have been previously assessed, the impact of more global mea... Read More about P6029Impact of elixhauser comorbidity score on the outcomes of transcatheter aortic valve replacement.

P4592Trends in prognosis and management of acute coronary syndromes using combined bleeding and ischaemic risk assessment - a retrospective analysis of MINAP data (2018)
Journal Article
Mohamed, M. O., Kinnaird, T., Kwok, C. S., Rashid, M., Anderson, R., Martin, G., …Mamas, M. A. (2018). P4592Trends in prognosis and management of acute coronary syndromes using combined bleeding and ischaemic risk assessment - a retrospective analysis of MINAP data. European Heart Journal, 39(suppl_1), https://doi.org/10.1093/eurheartj/ehy563.p4592

Background: Patients presenting with acute coronary syndrome (ACS) represent a heterogeneous population with various risk factors for coronary ischaemia and bleeding. Current ESC guidelines recommend potent dual antiplatelet therapy (DAPT), and cardi... Read More about P4592Trends in prognosis and management of acute coronary syndromes using combined bleeding and ischaemic risk assessment - a retrospective analysis of MINAP data.

Effect of Antiplatelet Therapy (Aspirin + Dipyridamole Versus Clopidogrel) on Mortality Outcome in Ischemic Stroke (2018)
Journal Article
Barlas, R. S., Loke, Y. K., Mamas, M. A., Bettencourt-Silva, J. H., Ford, I., Clark, A. B., …Myint, P. K. (2018). Effect of Antiplatelet Therapy (Aspirin + Dipyridamole Versus Clopidogrel) on Mortality Outcome in Ischemic Stroke. American Journal of Cardiology, 122(6), 1085-1090. https://doi.org/10.1016/j.amjcard.2018.05.043

The optimal regimen of antiplatelet therapy for secondary prevention in noncardioembolic ischemic stroke remains controversial. We aimed to determine which regimen was associated with the greatest reduction in adverse outcomes. We analysed prospectiv... Read More about Effect of Antiplatelet Therapy (Aspirin + Dipyridamole Versus Clopidogrel) on Mortality Outcome in Ischemic Stroke.