Outputs (12)

A prediction algorithm to improve the accuracy of the Gold Standard Framework Surprise Question end-of-life prognostic categories in an acute hospital admission cohort-controlled study. The Proactive Risk-Based and Data-Driven Assessment of Patients at the End of Life (PRADA) (2023)
Other
Singh, B., Kumari-Dewat, N., Ryder, A., Klaire, V., Bennion, G., Jennens, H., …Parry, E. (2023). A prediction algorithm to improve the accuracy of the Gold Standard Framework Surprise Question end-of-life prognostic categories in an acute hospital admission cohort-controlled study. The Proactive Risk-Based and Data-Driven Assessment of Patients at the End of Life (PRADA). [preprint]

Objective To determine the accuracy of a clinical data algorithm allocated end-of-life prognosis amongst hospital inpatients.

Method The model allocated a predicted Gold Standard Framework end-of-life prognosis to all acute medical patients admitt... Read More about A prediction algorithm to improve the accuracy of the Gold Standard Framework Surprise Question end-of-life prognostic categories in an acute hospital admission cohort-controlled study. The Proactive Risk-Based and Data-Driven Assessment of Patients at the End of Life (PRADA).

A transcriptomics-based drug repositioning approach to identify drugs with similar activities for the treatment of muscle pathologies in spinal muscular atrophy (SMA) models (2023)
Other
JM, H., E, M., ER, S., Ö, Ç., P, P., M, D., …M, B. (2023). A transcriptomics-based drug repositioning approach to identify drugs with similar activities for the treatment of muscle pathologies in spinal muscular atrophy (SMA) models. [Preprint]

VESCA’s variable precision: Determining the accuracy of adjustment for examiner differences in distributed OSCEs (2023)
Other
Yeates, P., & McCray, G. (2023). VESCA’s variable precision: Determining the accuracy of adjustment for examiner differences in distributed OSCEs

Eliciting and prioritising determinants of improved care in Multiple Long Term Health Conditions (MLTC): A modified online Delphi study (2023)
Other
Simpson, G., Stuart, B., Hijryana, M., Kwame Akyea, R., Stokes, J., Gibson, J., …Dambha-Miller, H. (2023). Eliciting and prioritising determinants of improved care in Multiple Long Term Health Conditions (MLTC): A modified online Delphi study. [Preprint article]

Differential effect of Fas activation on spinal muscular atrophy motoneuron death and induction of axonal growth (2022)
Other
Hilaire, C., Benlefki, S., Younes, R., Challuau, D., Bernard-Marissal, N., Scamps, F., …Raoul, C. (2022). Differential effect of Fas activation on spinal muscular atrophy motoneuron death and induction of axonal growth

Amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA) are the most common motoneuron diseases affecting adults and infants, respectively. ALS and SMA are both characterized by the selective degeneration of motoneurons. Although differ... Read More about Differential effect of Fas activation on spinal muscular atrophy motoneuron death and induction of axonal growth.

Risk-based stratified primary care for common musculoskeletal pain presentations: qualitative findings from the STarT MSK cluster randomised controlled trial (2022)
Other
Saunders, B., Chudyk, A., Protheroe, J., Cooper, V., Bartlam, B., Birkinshaw, H., …Hill, J. C. (2022). Risk-based stratified primary care for common musculoskeletal pain presentations: qualitative findings from the STarT MSK cluster randomised controlled trial. [preprint]

Blood biochemical parameters as predictors of disease severity and mortality in COVID-19 patients- an updated systematic review and meta-analysis (2021)
Other
Majid, A., Mishra, P., Parveen, R., Bajpai, R., Khan, M., & Agarwal, N. (2021). Blood biochemical parameters as predictors of disease severity and mortality in COVID-19 patients- an updated systematic review and meta-analysis

<h4>ABSTRACT</h4> <h4>Background</h4> The outbreak of coronavirus disease 2019 (COVID-19) has been rapidly spreading across the globe and poses a great risk to human health. Patients with abnormalities in laboratory parameters are more susceptible to... Read More about Blood biochemical parameters as predictors of disease severity and mortality in COVID-19 patients- an updated systematic review and meta-analysis.

Effect of lumbopelvic control on landing mechanics and lower extremity muscles' activities in female professional athletes: implications for injury prevention. (2021)
Other
(2021). Effect of lumbopelvic control on landing mechanics and lower extremity muscles' activities in female professional athletes: implications for injury prevention

BACKGROUND: Lumbopelvic control (LPC) has recently been associated with function, kinesiology, and load distribution on the limb. However, poor LPC has not been studied as a risk factor for lower limb injury in sports requiring frequent jump landings... Read More about Effect of lumbopelvic control on landing mechanics and lower extremity muscles' activities in female professional athletes: implications for injury prevention..

Dystrophin regulates peripheral circadian SRF signalling (2021)
Other
Betts, C. A., Jagannath, A., van Westering, T. L., Bowerman, M., Banerjee, S., Meng, J., …Wood, M. J. (2021). Dystrophin regulates peripheral circadian SRF signalling

Dystrophin is a sarcolemmal protein essential for muscle contraction and maintenance, absence of which leads to the devastating muscle wasting disease Duchenne muscular dystrophy (DMD)[1, 2]. Dystrophin has an actin-binding domain [3–5], which specif... Read More about Dystrophin regulates peripheral circadian SRF signalling.

ICS Material: a new method of managing patients with low back pain (stratified care), improves patients' outcomes, reduces costs and assists in the reduction of global burden (2019)
Other
(2019). ICS Material: a new method of managing patients with low back pain (stratified care), improves patients' outcomes, reduces costs and assists in the reduction of global burden

Good musculoskeletal (MSK) health is integral to a full working life. It supports us with functional mobility and dexterity, balance and co-ordination, and contributes to muscular strength and endurance; essential to nearly all forms of work. It also... Read More about ICS Material: a new method of managing patients with low back pain (stratified care), improves patients' outcomes, reduces costs and assists in the reduction of global burden.