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Outputs (623)

Clinical Pathway for Coronary Atherosclerosis in Patients Without Conventional Modifiable Risk Factors JACC State-of-the-Art Review (2023)
Journal Article
Figtree, G. A., Vernon, S. T., Harmer, J. A., Gray, M. P., Arnott, C., Bachour, E., …Nicholls, S. J. (in press). Clinical Pathway for Coronary Atherosclerosis in Patients Without Conventional Modifiable Risk Factors JACC State-of-the-Art Review. Journal of the American College of Cardiology, 82(13), 1343-1359. https://doi.org/10.1016/j.jacc.2023.06.045

Reducing the incidence and prevalence of standard modifiable cardiovascular risk factors (SMuRFs) is critical to tackling the global burden of coronary artery disease (CAD). However, a substantial number of individuals develop coro... Read More about Clinical Pathway for Coronary Atherosclerosis in Patients Without Conventional Modifiable Risk Factors JACC State-of-the-Art Review.

Catheter Event Rates in Medical Compared to Surgical Peritoneal Dialysis Catheter Insertion (2023)
Journal Article
Fotheringham, J., Solis-Trapala, I., Briggs, V., Lambie, M., McCullough, K., Dunn, L., …Wilkie, M. (2023). Catheter Event Rates in Medical Compared to Surgical Peritoneal Dialysis Catheter Insertion. Kidney International Reports, 8(12), 2635-2645. https://doi.org/10.1016/j.ekir.2023.09.015

How patient, center, and insertion technique factors interact needs to be understood when designing peritoneal dialysis (PD) catheter insertion pathways. We undertook a prospective cohort study in 44 UK centers enrolling participants planned for firs... Read More about Catheter Event Rates in Medical Compared to Surgical Peritoneal Dialysis Catheter Insertion.

Readmissions After Left Atrial Appendage Closure in Patients with Previous Ischemic Stroke or Transient Ischemic Attack (2023)
Journal Article
Sparrow, R. T., Sposato, L. A., Alkhouli, M. A., García, S., Elgendy, I. Y., Kuchtaruk, A. A., …Bagur, R. (2023). Readmissions After Left Atrial Appendage Closure in Patients with Previous Ischemic Stroke or Transient Ischemic Attack. CJC Open, 5(12), 950-964. https://doi.org/10.1016/j.cjco.2023.09.009

Background We examined the frequency and risk factors associated with readmissions after left atrial appendage closure (LAAC) in patients with and without previous ischemic stroke/transient ischemic attack (TIA). Methods Hospitali... Read More about Readmissions After Left Atrial Appendage Closure in Patients with Previous Ischemic Stroke or Transient Ischemic Attack.

The OARSI Joint Effort Initiative: Priorities for osteoarthritis management program implementation and research 2024-2028. (2023)
Journal Article
Bowden, J. L., Hunter, D. J., Mills, K., Allen, K., Bennell, K., Briggs, A. M., …Eyles, J. (2023). The OARSI Joint Effort Initiative: Priorities for osteoarthritis management program implementation and research 2024-2028. Osteoarthritis and Cartilage Open, 5(4), 100408. https://doi.org/10.1016/j.ocarto.2023.100408

The Joint Effort Initiative (JEI) is an international collaboration of clinicians, researchers, and consumer organisations with a shared vision of improving the implementation of osteoarthritis management programs (OAMPs). This study aimed to identif... Read More about The OARSI Joint Effort Initiative: Priorities for osteoarthritis management program implementation and research 2024-2028..

Outcomes and Discriminatory Accuracy of the CHA2DS2VASc Score in Atrial Fibrillation and Cancer (2023)
Journal Article
Ullah, W., DiMeglio, M., Frisch, D. R., Bagur, R., Sun, L. Y., Fischman, D. L., …Mamas, M. A. (2023). Outcomes and Discriminatory Accuracy of the CHA2DS2VASc Score in Atrial Fibrillation and Cancer. JACC: Advances, 2(8), 100609. https://doi.org/10.1016/j.jacadv.2023.100609

Background Atrial fibrillation (AF) is highly prevalent among cancer patients. The role of traditional risk stratification scores in the context of different cancer types in these patients remains unknown.... Read More about Outcomes and Discriminatory Accuracy of the CHA2DS2VASc Score in Atrial Fibrillation and Cancer.

Iron oxide nanoparticles as a new tool for treating cardiovascular diseases (2023)
Conference Proceeding
Cabrera, D., Ranjbar, J., Santana-Otero, A., Sharifabad, M. E., Ortega, D., Telling, N. D., & Harper, A. (2023). Iron oxide nanoparticles as a new tool for treating cardiovascular diseases. . https://doi.org/10.1109/intermagshortpapers58606.2023.10228198

Thrombotic events are a major cause of death and disability worldwide. Thrombolysis with the clot busting drug tissue plasminogen activator (tPA) or thromboprophylaxis using anticoagulants such as heparin are frontline treatments for thrombotic disea... Read More about Iron oxide nanoparticles as a new tool for treating cardiovascular diseases.

Risk-stratified monitoring for thiopurine toxicity in immune-mediated inflammatory diseases: prognostic model development, validation, and, health economic evaluation. (2023)
Journal Article
Nakafero, G., Card, T., Grainge, M. J., Williams, H. C., Taal, M. W., Aithal, G. P., …Abhishek, A. (2023). Risk-stratified monitoring for thiopurine toxicity in immune-mediated inflammatory diseases: prognostic model development, validation, and, health economic evaluation. EClinicalMedicine, 64, Article 102213. https://doi.org/10.1016/j.eclinm.2023.102213

Background Patients established on thiopurines (e.g., azathioprine) are recommended to undergo three-monthly blood tests for the early detection of blood, liver, or kidney toxicity. These side-effects are uncommon during long-term treatment. We deve... Read More about Risk-stratified monitoring for thiopurine toxicity in immune-mediated inflammatory diseases: prognostic model development, validation, and, health economic evaluation..

Substance Use in Pregnancy and its Association With Cardiovascular Events (2023)
Journal Article
Evans, K., Wu, P., Mamas, M. A., Irwin, C., Kang, P., Perlow, J. H., …Gulati, M. (2023). Substance Use in Pregnancy and its Association With Cardiovascular Events. JACC: Advances, 2(8), 100619. https://doi.org/10.1016/j.jacadv.2023.100619

Background Substance use and cardiovascular (CV) events are increasing among pregnant women in the United States, but association between substance use in pregnancy and CV events remains unknown. Objectives The purpose of this stu... Read More about Substance Use in Pregnancy and its Association With Cardiovascular Events.

Human vascularised synovium-on-a-chip: a mechanically stimulated, microfluidic model to investigate synovial inflammation and monocyte recruitment. (2023)
Journal Article
Thompson, C. L., Hopkins, T., Bevan, C., Screen, H. R., Wright, K. T., & Knight, M. M. (in press). Human vascularised synovium-on-a-chip: a mechanically stimulated, microfluidic model to investigate synovial inflammation and monocyte recruitment. Biomedical Materials, 18(6), https://doi.org/10.1088/1748-605X/acf976

Healthy synovium is critical for joint homeostasis. Synovial inflammation (synovitis) is implicated in the onset, progression and symptomatic presentation of arthritic joint diseases such as rheumatoid arthritis (RA) and osteoarthritis (OA). Thus, th... Read More about Human vascularised synovium-on-a-chip: a mechanically stimulated, microfluidic model to investigate synovial inflammation and monocyte recruitment..