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Outputs (5131)

Mobilising the experiential knowledge of clinicians, patients and carers for applied health-care research (2013)
Journal Article
Carter, P., Beech, R., Coxon, D., Thomas, M. J., & Jinks, C. (2013). Mobilising the experiential knowledge of clinicians, patients and carers for applied health-care research. Contemporary Social Science, 8(3), 307-320. https://doi.org/10.1080/21582041.2013.767468

This article demonstrates the benefits of combining various types of knowledge for applied health research. Funding is available for health research despite these being ‘austere times’ for public services and international policy shifts recognise the... Read More about Mobilising the experiential knowledge of clinicians, patients and carers for applied health-care research.

Statin Use and Clinical Osteoarthritis in the General Population: A Longitudinal Study (2013)
Journal Article
Kadam, U. T., Blagojevic, M., & Belcher, J. (2013). Statin Use and Clinical Osteoarthritis in the General Population: A Longitudinal Study. Journal of General Internal Medicine, 28(7), 943-949. https://doi.org/10.1007/s11606-013-2382-8

BACKGROUND: One hypothesis has posited whether abnormal lipid metabolism might be a causal factor in the pathogenesis of osteoarthritis (OA). Routine statin use in clinical practice provides the basis for a natural experiment in testing this hypothes... Read More about Statin Use and Clinical Osteoarthritis in the General Population: A Longitudinal Study.

Recruitment of UBPY and ESCRT Exchange Drive HD-PTP-Dependent Sorting of EGFR to the MVB (2013)
Journal Article
Ali, N., Zhang, L., Taylor, S., Mironov, A., Urbé, S., & Woodman, P. (2013). Recruitment of UBPY and ESCRT Exchange Drive HD-PTP-Dependent Sorting of EGFR to the MVB. Current Biology, 23(6), 453 - 461. https://doi.org/10.1016/j.cub.2013.02.033

Background Sorting ubiquitinated epidermal growth factor receptor (EGFR) to the intralumenal vesicles of the multivesicular body requires the coordinated action of several ESCRT complexes. A central question is how EGFR transits vectorially from ear... Read More about Recruitment of UBPY and ESCRT Exchange Drive HD-PTP-Dependent Sorting of EGFR to the MVB.

Tips for GP trainees working in rheumatology (2013)
Journal Article
Welsh, V. (2013). Tips for GP trainees working in rheumatology. British Journal of General Practice (BJGP), 63(608), 164-165. https://doi.org/10.3399/bjgp13x664450

INTRODUCTION One in four people registered with a GP will consult for a musculoskeletal problem over a 12-month period; this accounts for one in seven GP consultations.1 Musculoskeletal conditions significantly impact daily life through pain, disabi... Read More about Tips for GP trainees working in rheumatology.

Stem cell therapy for ischaemic stroke: translation from preclinical studies to clinical treatment (2013)
Journal Article
Balami, J. S., Fricker, R. A., & Chen, R. (2013). Stem cell therapy for ischaemic stroke: translation from preclinical studies to clinical treatment. CNS & Neurological Disorders - Drug Targets, 12(2), 209 -219. https://doi.org/10.2174/1871527311312020007

No pharmacological intervention has been shown convincingly to improve neurological outcome in stroke patients after the brain tissue is infarcted. While conventional therapeutic strategies focus on preventing brain damage, stem cell treatment has th... Read More about Stem cell therapy for ischaemic stroke: translation from preclinical studies to clinical treatment.

Operationalising unscheduled care policy: a qualitative study of healthcare professionals’ perspectives (2013)
Journal Article
Drinkwater, J., Salmon, P., Langer, S., Hunter, C., Stenhoff, A., Guthrie, E., & Chew-Graham, C. (2013). Operationalising unscheduled care policy: a qualitative study of healthcare professionals’ perspectives. British Journal of General Practice (BJGP), 63(608), e192-e199. https://doi.org/10.3399/bjgp13x664243

Background UK health policy aims to reduce the use of unscheduled care, by increasing proactive and preventative management of patients with long-term conditions in primary care. Aim The study explored healthcare professionals’ understanding of wh... Read More about Operationalising unscheduled care policy: a qualitative study of healthcare professionals’ perspectives.

Collaborative care for depression: a literature review and a model for implementation in developing countries (2013)
Journal Article
Farooq, S. (2013). Collaborative care for depression: a literature review and a model for implementation in developing countries. International Health, 5(1), 24-28. https://doi.org/10.1093/inthealth/ihs015

Depression will soon be the leading cause of disability in developing countries but effective treatments are not widely available. There is compelling evidence for the effectiveness and cost-effectiveness of the multicondition collaborative care (MCC... Read More about Collaborative care for depression: a literature review and a model for implementation in developing countries.

Slaying the dragon myth: an ethnographic study of receptionists in UK general practice (2013)
Journal Article
Hammond, J., Gravenhorst, K., Funnell, E., Beatty, S., Hibbert, D., Lamb, J., …Chew-Graham, C. A. (2013). Slaying the dragon myth: an ethnographic study of receptionists in UK general practice. British Journal of General Practice (BJGP), 63(608), e177-e184. https://doi.org/10.3399/bjgp13x664225

Background General practice receptionists fulfil an essential role in UK primary care, shaping patient access to health professionals. They are often portrayed as powerful ‘gatekeepers’. Existing literature and management initiatives advocate more tr... Read More about Slaying the dragon myth: an ethnographic study of receptionists in UK general practice.

Combined influence of gene-specific cord blood methylation and maternal smoking habit on birth weight (2013)
Journal Article
Haworth, K. E., Farrell, W. E., Emes, R. D., Ismail, K. M. K., Carroll, W. D., Borthwick, H. D., …Fryer, A. A. (2013). Combined influence of gene-specific cord blood methylation and maternal smoking habit on birth weight. Epigenomics, 5(1), 37-49. https://doi.org/10.2217/EPI.12.72

Aim: Evidence suggests that folic acid intake affects birth weight and that these effects may be mediated via the fetal epigenome. Our previous array data indicate that methylation in human cord blood at gene-specific CpGs is associated with birth we... Read More about Combined influence of gene-specific cord blood methylation and maternal smoking habit on birth weight.