Outputs (5131)

Magnetic Nanoparticle Labeling of Astrocytes Derived for Neural Transplantation (2010)
Journal Article
Pickard, M. R., Jenkins, S. I., Koller, C. J., Furness, D. N., & Chari, D. M. (2011). Magnetic Nanoparticle Labeling of Astrocytes Derived for Neural Transplantation. Tissue Engineering Part C: Methods, 17(1), 89-99. https://doi.org/10.1089/ten.tec.2010.0170

Astrocytes are a major transplant cell population to promote neural repair in a range of pathological conditions. In this context, the development of robust methods to label neural transplant populations (for subsequent detection and cell tracking in... Read More about Magnetic Nanoparticle Labeling of Astrocytes Derived for Neural Transplantation.

Anterior knee pain in younger adults as a precursor to subsequent patellofemoral osteoarthritis: a systematic review (2010)
Journal Article
(2010). Anterior knee pain in younger adults as a precursor to subsequent patellofemoral osteoarthritis: a systematic review. BMC Musculoskeletal Disorders, 201 -?. https://doi.org/10.1186/1471-2474-11-201

BACKGROUND: Patellofemoral osteoarthritis (PFOA) is a common form of knee OA in middle and older age, but its relation to PF disorders and symptoms earlier in life is unclear. Our aim was to conduct a systematic review to investigate the strength of... Read More about Anterior knee pain in younger adults as a precursor to subsequent patellofemoral osteoarthritis: a systematic review.

IMPaCT Back study protocol. Implementation of subgrouping for targeted treatment systems for low back pain patients in primary care: a prospective population-based sequential comparison (2010)
Journal Article
(2010). IMPaCT Back study protocol. Implementation of subgrouping for targeted treatment systems for low back pain patients in primary care: a prospective population-based sequential comparison. BMC Musculoskeletal Disorders, 186 - ?. https://doi.org/10.1186/1471-2474-11-186

Background Prognostic assessment tools to identify subgroups of patients at risk of persistent low back pain who may benefit from targeted treatments have been developed and validated in primary care. The IMPaCT Back study is investigating the effec... Read More about IMPaCT Back study protocol. Implementation of subgrouping for targeted treatment systems for low back pain patients in primary care: a prospective population-based sequential comparison.

What are the important components of the clinical assessment of hand problems in older adults in primary care? Results of a Delphi study (2010)
Journal Article
Dziedzic. (2010). What are the important components of the clinical assessment of hand problems in older adults in primary care? Results of a Delphi study. BMC Musculoskeletal Disorders, 178 -?. https://doi.org/10.1186/1471-2474-11-178

Background: To identify clinical questions and assessments regarded by health care practitioners as important when assessing undifferentiated hand pain or problems in adults aged 50 years and over presenting to primary care. Methods: A purposively... Read More about What are the important components of the clinical assessment of hand problems in older adults in primary care? Results of a Delphi study.

What is a pilot or feasibility study? A review of current practice and editorial policy. (2010)
Journal Article
(2010). What is a pilot or feasibility study? A review of current practice and editorial policy. BMC medical research methodology, 67 - ?. https://doi.org/10.1186/1471-2288-10-67

BACKGROUND: In 2004, a review of pilot studies published in seven major medical journals during 2000-01 recommended that the statistical analysis of such studies should be either mainly descriptive or focus on sample size estimation, while results fr... Read More about What is a pilot or feasibility study? A review of current practice and editorial policy..

Valproate and Bone Loss: iTRAQ Proteomics Show that Valproate Reduces Collagens and Osteonectin in SMA Cells (2010)
Journal Article
Fuller, H. R., Man, N. T., Lam, L. T., Shamanin, V. A., Androphy, E. J., & Morris, G. E. (2010). Valproate and Bone Loss: iTRAQ Proteomics Show that Valproate Reduces Collagens and Osteonectin in SMA Cells. Journal of Proteome Research, 9(8), 4228-4233. https://doi.org/10.1021/pr1005263

Valproate is commonly used as an anticonvulsant and mood stabilizer, but its long-term side-effects can include bone loss. As a histone deacetylase (HDAC) inhibitor, valproate has also been considered for treatment of spinal muscular atrophy (SMA). U... Read More about Valproate and Bone Loss: iTRAQ Proteomics Show that Valproate Reduces Collagens and Osteonectin in SMA Cells.

Trials in primary care: statistical issues in the design, conduct and evaluation of complex interventions (2010)
Journal Article
Lancaster, G. A., Campbell, M. J., Eldridge, S., Farrin, A., Marchant, M., Muller, S., …Rait, G. (2010). Trials in primary care: statistical issues in the design, conduct and evaluation of complex interventions. Statistical Methods in Medical Research, 19(4), 349-377. https://doi.org/10.1177/0962280209359883

An intercalated research Masters in primary care: a pilot programme. (2010)
Journal Article
Mallen. (2010). An intercalated research Masters in primary care: a pilot programme. Education for Primary Care, 208 - 211. https://doi.org/10.1080/14739879.2010.11493909

Academic medicine is said by some to be in decline and primary care in particular struggles to recruit to academic general practice posts at all levels. Intercalated degrees are often described as being a stepping-stone to an academic career, yet a B... Read More about An intercalated research Masters in primary care: a pilot programme..

Radiographic thumb osteoarthritis: frequency, patterns and associations with pain and clinical assessment findings in a community-dwelling population. (2010)
Journal Article
Marshall, M., Myers, H., Dziedzic, K., Nicholls, E., & Van Der Windt, D. (2010). Radiographic thumb osteoarthritis: frequency, patterns and associations with pain and clinical assessment findings in a community-dwelling population. Rheumatology, 50(4), 735 - 739. https://doi.org/10.1093/rheumatology/keq371

OBJECTIVES: The aim of this study was to investigate: (i) the frequency and patterns of radiographic OA (ROA) in the thumb joints; and (ii) associations between thumb ROA and the clinical characteristics of thumb OA in older adults with hand pain or... Read More about Radiographic thumb osteoarthritis: frequency, patterns and associations with pain and clinical assessment findings in a community-dwelling population..

The Staffordshire Arthritis, Musculoskeletal, and Back Assessment (SAMBA) Study: a prospective observational study of patient outcome following referral to a primary-secondary care musculoskeletal interface service (2010)
Journal Article
Jordan, Roddy, Zwierska, Hay, & Hider. (2010). The Staffordshire Arthritis, Musculoskeletal, and Back Assessment (SAMBA) Study: a prospective observational study of patient outcome following referral to a primary-secondary care musculoskeletal interface service. BMC Musculoskeletal Disorders, 67 -?. https://doi.org/10.1186/1471-2474-11-67

Background Recent healthcare policy has shifted the management of musculoskeletal conditions in the UK away from secondary care towards Clinical Assessment and Treatment Services at the primary-secondary care interface. However, little is known abou... Read More about The Staffordshire Arthritis, Musculoskeletal, and Back Assessment (SAMBA) Study: a prospective observational study of patient outcome following referral to a primary-secondary care musculoskeletal interface service.