Outputs (32)

Pilot study on virtual imaging for patient information on radiotherapy planning and delivery (2015)
Journal Article
Sule-Suso, J., Finney, S., Bisson, J., Hammersley, S., Jassel, S., Knight, R., …Moloney, A. (2015). Pilot study on virtual imaging for patient information on radiotherapy planning and delivery. Radiography, 273-277. https://doi.org/10.1016/j.radi.2015.02.002

It is widely accepted that health professionals might sometimes underestimate cancer patients' needs for information on the complex process of radiotherapy (RT) planning and delivery. Furthermore, relatives might also feel excluded from the treatment... Read More about Pilot study on virtual imaging for patient information on radiotherapy planning and delivery.

Probing single-tumor cell interactions with different-age type I collagen networks by synchrotron-based Fourier transform infrared microspectroscopy (2014)
Journal Article
Guilbert, M., Eklouh-Molinier, C., Wehbe, K., Sulé-Suso, J., Yang, Y., Cinque, G., …Sockalingum, G. D. (2014). Probing single-tumor cell interactions with different-age type I collagen networks by synchrotron-based Fourier transform infrared microspectroscopy. Journal of Biomedical Optics, 19(11), 111612. https://doi.org/10.1117/1.jbo.19.11.111612

We report here on a first study using synchrotron radiation-based Fourier transform infrared microspectroscopy and imaging to investigate HT1080 human fibrosarcoma cells grown onto different-aged type I collagen networks. Spectral images were analy... Read More about Probing single-tumor cell interactions with different-age type I collagen networks by synchrotron-based Fourier transform infrared microspectroscopy.

Using Fourier transform IR spectroscopy to analyze biological materials (2014)
Journal Article
Baker, M. J., Trevisan, J., Bassan, P., Bhargava, R., Butler, H. J., Dorling, K. M., …Martin, F. L. (2014). Using Fourier transform IR spectroscopy to analyze biological materials. Nature Protocols, 9(8), 1771-1791. https://doi.org/10.1038/nprot.2014.110

IR spectroscopy is an excellent method for biological analyses. It enables the nonperturbative, label-free extraction of biochemical information and images toward diagnosis and the assessment of cell functionality. Although not strictly microscopy in... Read More about Using Fourier transform IR spectroscopy to analyze biological materials.

Study of gemcitabine-sensitive/resistant cancer cells by cell cloning and synchrotron FTIR microspectroscopy (2014)
Journal Article
Rutter, A. V., Siddique, M. R., Filik, J., Sandt, C., Dumas, P., Cinque, G., …Sulé-Suso, J. (2014). Study of gemcitabine-sensitive/resistant cancer cells by cell cloning and synchrotron FTIR microspectroscopy. Cytometry Part A, 85(8), 688-697. https://doi.org/10.1002/cyto.a.22488

Over the last few years, significant scientific insight on the effects of chemotherapy drugs at cellular level using synchrotron-based FTIR (S-FTIR) microspectroscopy has been obtained. The work carried out so far has identified spectral differences... Read More about Study of gemcitabine-sensitive/resistant cancer cells by cell cloning and synchrotron FTIR microspectroscopy.

Study of the biochemical effects induced by X-ray irradiations in combination with gadolinium nanoparticles in F98 glioma cells: first FTIR studies at the Emira laboratory of the SESAME synchrotron (2014)
Journal Article
Yousef, I., Seksek, O., Gil, S., Prezado, Y., Sulé-Suso, J., & Martínez-Rovira, I. (2014). Study of the biochemical effects induced by X-ray irradiations in combination with gadolinium nanoparticles in F98 glioma cells: first FTIR studies at the Emira laboratory of the SESAME synchrotron. Analyst, 141(7), 2238-2249. https://doi.org/10.1039/c5an02378e

Over the last few years, significant scientific insight on the effects of chemotherapy drugs at cellular level using synchrotron-based FTIR (S-FTIR) microspectroscopy has been obtained. The work carried out so far has identified spectral differences... Read More about Study of the biochemical effects induced by X-ray irradiations in combination with gadolinium nanoparticles in F98 glioma cells: first FTIR studies at the Emira laboratory of the SESAME synchrotron.

Vibrational spectroscopy in stem cell characterisation: is there a niche? (2014)
Journal Article
Sulé-Suso, J., Forsyth, N., Untereiner, V., & Sockalingum, G. (2014). Vibrational spectroscopy in stem cell characterisation: is there a niche?. Trends in Biotechnology, 32(5), 254-262. https://doi.org/10.1016/j.tibtech.2014.03.002

Vibrational spectroscopy using both infrared and Raman spectroscopies has been used in recent years with the aim to aid clinicians in disease diagnosis. More recently, these techniques have been applied to study stem cell differentiation and to deter... Read More about Vibrational spectroscopy in stem cell characterisation: is there a niche?.

On evaluation of a multiscale-based CT image analysis and visualisation algorithm (2013)
Conference Proceeding
Lam, K., Collins, D., Sule-Suso, J., Bhana, R., & Moloney, A. (2013). On evaluation of a multiscale-based CT image analysis and visualisation algorithm. . https://doi.org/10.1109/BMEI.2013.6746924

Development of computed tomography (CT) protocols that minimise radiation dose for specific clinical treatments continues to be a major research focus. Building on the success of an earlier collaborative case study concerning prostate cancer diagnosi... Read More about On evaluation of a multiscale-based CT image analysis and visualisation algorithm.

A microscopic and macroscopic study of aging collagen on its molecular structure, mechanical properties, and cellular response (2013)
Journal Article
Wilson, S. L., Guilbert, M., Sulé‐Suso, J., Torbet, J., Jeannesson, P., Sockalingum, G. D., & Yang, Y. (2014). A microscopic and macroscopic study of aging collagen on its molecular structure, mechanical properties, and cellular response. FASEB Journal, 28(1), 14-25. https://doi.org/10.1096/fj.13-227579

During aging, collagen structure changes, detrimentally affecting tissues' biophysical and biomechanical properties due to an accumulation of advanced glycation end-products (AGEs). In this investigation, we conducted a parallel study of microscopic... Read More about A microscopic and macroscopic study of aging collagen on its molecular structure, mechanical properties, and cellular response.

Anti-cancer thymoquinone from Nigella sativa (2013)
Journal Article
Li, W., Rosa, J., Siddique, M., Bajana, B., Sulé-Suso, J., & Richardson, A. Anti-cancer thymoquinone from Nigella sativa. Planta Medica, 79(13), https://doi.org/10.1055/s-0033-1351896

Quinones and phenolic compounds are important bioactive natural products in medicinal and dietary plants [1 – 3]. For example, thymoquinone (2-isopropyl-6-methyl-1,4-benzoquinone, TQ) is the main bioactive compound from Nigella sativa (black cumin) (... Read More about Anti-cancer thymoquinone from Nigella sativa.

Identification of different subsets of lung cells using Raman microspectroscopy and whole cell nucleus isolation (2013)
Journal Article
Pijanka, J. K., Stone, N., Rutter, A. V., Forsyth, N., Sockalingum, G. D., Yang, Y., & Sulé-Suso, J. (2013). Identification of different subsets of lung cells using Raman microspectroscopy and whole cell nucleus isolation. Analyst, 138(17), 5052. https://doi.org/10.1039/c3an00968h

Raman spectroscopy has been widely used to study its possible clinical application in cancer diagnosis. However, in order to make it into clinical practice, it is important that this technique is able not only to identify cancer cells from their norm... Read More about Identification of different subsets of lung cells using Raman microspectroscopy and whole cell nucleus isolation.