Outputs (7)

Parallelized Manipulation of Adherent Living Cells by Magnetic Nanoparticles-Mediated Forces (2020)
Journal Article
Coppey, M., Piehler, J., Gates, M., Neumann, S., Telling, N., Heumann, R., …Raudzus, F. (2020). Parallelized Manipulation of Adherent Living Cells by Magnetic Nanoparticles-Mediated Forces. International Journal of Molecular Sciences, 21(18), https://doi.org/10.3390/ijms21186560

The remote actuation of cellular processes such as migration or neuronal outgrowth is a challenge for future therapeutic applications in regenerative medicine. Among the different methods that have been proposed, the use of magnetic nanoparticles app... Read More about Parallelized Manipulation of Adherent Living Cells by Magnetic Nanoparticles-Mediated Forces.

Cytotoxic effect of PEI-coated magnetic nanoparticles on the regulation of cellular focal adhesions and actin stress fibres (2020)
Journal Article
Telling. (2020). Cytotoxic effect of PEI-coated magnetic nanoparticles on the regulation of cellular focal adhesions and actin stress fibres. https://doi.org/10.2139/ssrn.3558242

The biocompatibility of surface-coated magnetic nanoparticles (MNPs) is key to their successful use in biomedical applications. Polyethyleneimine-coated MNPs (MNP-PEIs) provide improved in vitro nucleic acid transfection efficiency and are safer comp... Read More about Cytotoxic effect of PEI-coated magnetic nanoparticles on the regulation of cellular focal adhesions and actin stress fibres.

Controlling human platelet activation with calcium-binding nanoparticles (2020)
Journal Article
Cabrera, D., Walker, K., Moise, S., Telling, N. D., & Harper, A. G. (2020). Controlling human platelet activation with calcium-binding nanoparticles. Nano Research, 13, Article 2697–2705. https://doi.org/10.1007/s12274-020-2912-8

We introduce a neural method that is able to fuse concepts from a knowledge base with the context information for the task of grouping of aspect terms. Rather than only using context information, we use the corresponding concepts of aspect terms as a... Read More about Controlling human platelet activation with calcium-binding nanoparticles.

Iron stored in ferritin is chemically reduced in the presence of aggregating Aß(1-42). (2020)
Journal Article
Everett, J., Brooks, J., Lermyte, F., O’Connor, P. B., Sadler, P. J., Dobson, J., …Telling, N. D. (2020). Iron stored in ferritin is chemically reduced in the presence of aggregating Aß(1-42). Scientific reports, 20, Article 10332. https://doi.org/10.1038/s41598-020-67117-z

Atypical low-oxidation-state iron phases in Alzheimer's disease (AD) pathology are implicated in disease pathogenesis, as they may promote elevated redox activity and convey toxicity. However, the origin of low-oxidation-state iron and the pathways r... Read More about Iron stored in ferritin is chemically reduced in the presence of aggregating Aß(1-42)..

Analysis of neuronal iron deposits in Parkinson's disease brain tissue by synchrotron x-ray spectromicroscopy. (2020)
Journal Article
Brooks, J., Everett, J., Lermyte, F., Tjendana Tjhin, V., Sadler, P. J., Telling, N., & Collingwood, J. F. (2020). Analysis of neuronal iron deposits in Parkinson's disease brain tissue by synchrotron x-ray spectromicroscopy. Journal of Trace Elements in Medicine and Biology, 62, Article 126555. https://doi.org/10.1016/j.jtemb.2020.126555

BACKGROUND: Neuromelanin-pigmented neurons, which are highly susceptible to neurodegeneration in the Parkinson's disease substantia nigra, harbour elevated iron levels in the diseased state. Whilst it is widely believed that neuronal iron is stored i... Read More about Analysis of neuronal iron deposits in Parkinson's disease brain tissue by synchrotron x-ray spectromicroscopy..

Label-Free Nanoimaging of Neuromelanin in the Brain by Soft X-ray Spectromicroscopy. (2020)
Journal Article
Telling, & Everett. (2020). Label-Free Nanoimaging of Neuromelanin in the Brain by Soft X-ray Spectromicroscopy. Angewandte Chemie International Edition, https://doi.org/10.1002/anie.202000239

A hallmark of Parkinson's disease is the death of neuromelanin-pigmented neurons, but the role of neuromelanin is unclear. The in situ characterization of neuromelanin remains dependent on detectable pigmentation, rather than direct quantification of... Read More about Label-Free Nanoimaging of Neuromelanin in the Brain by Soft X-ray Spectromicroscopy..

Broadband optical measurement of AC magnetic susceptibility of magnetite nanoparticles (2020)
Journal Article
Soucaille, R., Sharifabad, M., Telling, N., & Hicken, R. (2020). Broadband optical measurement of AC magnetic susceptibility of magnetite nanoparticles. Applied Physics Letters, 116(6), 062404 - 062404. https://doi.org/10.1063/1.5140362

Characterization of magnetic nanoparticles in solution is challenging due to the interplay between magnetic relaxation and agglomeration. The AC magnetic susceptibility of magnetite nanoparticles in water has been studied using magneto-optical method... Read More about Broadband optical measurement of AC magnetic susceptibility of magnetite nanoparticles.