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HIF prolyl hydroxylase inhibition prior to transient focal cerebral ischaemia is neuroprotective in mice (2014)
Journal Article
Chen, R. L., Ogunshola, O. O., Yeoh, K. K., Jani, A., Papadakis, M., Nagel, S., …Buchan, A. M. (2014). HIF prolyl hydroxylase inhibition prior to transient focal cerebral ischaemia is neuroprotective in mice. Journal of Neurochemistry, 131(2), 177-189. https://doi.org/10.1111/jnc.12804

This study investigated the effects of 2-(1-chloro-4-hydroxyisoquinoline-3-carboxamido) acetic acid (IOX3), a selective small molecule inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylases, on mouse brains subject to transient focal cerebra... Read More about HIF prolyl hydroxylase inhibition prior to transient focal cerebral ischaemia is neuroprotective in mice.

Changes of synovial fluid protein concentrations in supra-patellar bursitis patients after the injection of different molecular weights of hyaluronic acid (2014)
Journal Article
Chen, C. P., Hsu, C. C., Pei, Y., Chen, R. L., Zhou, S., Shen, H., …Tsai, W. C. (2014). Changes of synovial fluid protein concentrations in supra-patellar bursitis patients after the injection of different molecular weights of hyaluronic acid. Experimental Gerontology, 52, 30-35. https://doi.org/10.1016/j.exger.2014.01.016

Knee pain is commonly seen in orthopedic and rehabilitation outpatient clinical settings, and in the aging population. Bursitis of the knee joint, especially when the volume of the synovial fluid is large enough, can compress and distend the nearby s... Read More about Changes of synovial fluid protein concentrations in supra-patellar bursitis patients after the injection of different molecular weights of hyaluronic acid.