Outputs (36)

Spinal motor neurite outgrowth over glial scar inhibitors is enhanced by coculture with bone marrow stromal cells. (2014)
Journal Article
Wright, K., & Roberts, S. (2014). Spinal motor neurite outgrowth over glial scar inhibitors is enhanced by coculture with bone marrow stromal cells. Spine Journal, 1722 - 1733. https://doi.org/10.1016/j.spinee.2014.01.021

BACKGROUND CONTEXT: Transplantation of bone marrow cells into spinal cord lesions promotes functional recovery in animal models, and recent clinical trials suggest possible recovery also in humans. The mechanisms responsible for these improvements ar... Read More about Spinal motor neurite outgrowth over glial scar inhibitors is enhanced by coculture with bone marrow stromal cells..

Characterization of the cells in repair tissue following autologous chondrocyte implantation in mankind: a novel report of two cases (2013)
Journal Article
Wright, K. T., Mennan, C., Fox, H., Richardson, J. B., Banerjee, R., & Roberts, S. (2013). Characterization of the cells in repair tissue following autologous chondrocyte implantation in mankind: a novel report of two cases. Regenerative Medicine, 8(6), 699 - 709. https://doi.org/10.2217/rme.13.67

AIM: Autologous chondrocyte implantation (ACI) is used worldwide for the treatment of cartilage defects. This study has aimed to assess for the first time the cells that are contained within human ACI repair tissues several years post-treatment. We h... Read More about Characterization of the cells in repair tissue following autologous chondrocyte implantation in mankind: a novel report of two cases.

A histological comparison of the repair tissue formed when using either Chondrogide® or periosteum during autologous chondrocyte implantation (2013)
Journal Article
McCarthy, H., & Roberts, S. (2013). A histological comparison of the repair tissue formed when using either Chondrogide® or periosteum during autologous chondrocyte implantation. Osteoarthritis and Cartilage, 21(12), 2048-2057. https://doi.org/10.1016/j.joca.2013.10.004

Objective In this study, we compare the clinical and histological outcome between periosteum and Chondrogide® during autologous chondrocyte implantation (ACI). Method This study consisted of 88 patients having received ACI in the knee; 33 treate... Read More about A histological comparison of the repair tissue formed when using either Chondrogide® or periosteum during autologous chondrocyte implantation.

Increased production of clusterin in biopsies of repair tissue following autologous chondrocyte implantation (2013)
Journal Article
McCarthy, H. S., Malda, J., Richardson, J. B., & Roberts, S. (2013). Increased production of clusterin in biopsies of repair tissue following autologous chondrocyte implantation. Cartilage, 4(3), 227 -238. https://doi.org/10.1177/1947603513477652

OBJECTIVE: To characterize the immunolocalization of clusterin in the repair cartilage of patients having undergone autologous chondrocyte implantation (ACI) and evaluate correlation to clinical outcome. DESIGN: Full-depth core biopsies of repair tis... Read More about Increased production of clusterin in biopsies of repair tissue following autologous chondrocyte implantation.

Isolation and characterisation of mesenchymal stem cells from different regions of the human umbilical cord. (2013)
Journal Article
Mennan, C., Wright, K., Bhattacharjee, A., Balain, B., Richardson, J., & Roberts, S. (2013). Isolation and characterisation of mesenchymal stem cells from different regions of the human umbilical cord. BioMed Research International, 2013, Article 916136. https://doi.org/10.1155/2013/916136

Umbilical cords as a source of stem cells are of increasing interest for cell therapies as they present little ethical consideration and are reported to contain immune privileged cells which may be suitable for allogeneic based therapies. Mesenchymal... Read More about Isolation and characterisation of mesenchymal stem cells from different regions of the human umbilical cord..

Fourier transform infrared imaging and infrared fiber optic probe spectroscopy identify collagen type in connective tissues (2013)
Journal Article
Hanifi, A., McCarthy, H., Roberts, S., & Pleshko, N. (2013). Fourier transform infrared imaging and infrared fiber optic probe spectroscopy identify collagen type in connective tissues. PloS one, 8(5), Article e64822. https://doi.org/10.1371/journal.pone.0064822

Hyaline cartilage and mechanically inferior fibrocartilage consisting of mixed collagen types are frequently found together in repairing articular cartilage. The present study seeks to develop methodology to identify collagen type and other tissue co... Read More about Fourier transform infrared imaging and infrared fiber optic probe spectroscopy identify collagen type in connective tissues.