Outputs (42)

Single-Molecule Detection of 5-Hydroxymethylcytosine in DNA through Chemical Modification and Nanopore Analysis (2013)
Journal Article
Li, W., Gong, L., & Bayley, H. (2013). Single-Molecule Detection of 5-Hydroxymethylcytosine in DNA through Chemical Modification and Nanopore Analysis. Angewandte Chemie International Edition, 52(16), 4350-4355. https://doi.org/10.1002/anie.201300413

DNA threading the needle: A new method of single-molecule detection of 5-hydroxymethylcytosine (5hmC) in DNA has been developed. Selective thiol substitution of 5hmC (giving SMC) in a single-step, bisulfite-mediated reaction (see scheme) allows the i... Read More about Single-Molecule Detection of 5-Hydroxymethylcytosine in DNA through Chemical Modification and Nanopore Analysis.

De novo design, synthesis, and characterization of quinoproteins (2006)
Journal Article
Li, W., Hellwig, P., Ritter, M., & Haehnel, W. (2006). De novo design, synthesis, and characterization of quinoproteins. Chemistry - A European Journal, 12(27), 7236-7245. https://doi.org/10.1002/chem.200501212

Quinones and quinoproteins are essential redox components and enzymes in biological systems. Here, we report the de novo design, synthesis, and properties of model four-α-helix bundle quinoproteins. The proteins were designed and constructed from thr... Read More about De novo design, synthesis, and characterization of quinoproteins.