Outputs (108)

A qualitative study of cardiac rehabilitation patients' perspectives on taking medicines: implications for the 'medicines-resistance' model of medicine-taking (2013)
Journal Article
White. (2013). A qualitative study of cardiac rehabilitation patients' perspectives on taking medicines: implications for the 'medicines-resistance' model of medicine-taking. BMC Health Services Research, 302 -?. https://doi.org/10.1186/1472-6963-13-302

BACKGROUND: The appropriate use of medicines continues to be an important area of inter-disciplinary research activity both in the UK and beyond. Key qualitative work in this area in the last decade has included the 'medicines resistance' model of me... Read More about A qualitative study of cardiac rehabilitation patients' perspectives on taking medicines: implications for the 'medicines-resistance' model of medicine-taking.

Albumin reduces paracentesis induced circulatory dysfunction and reduces death and renal impairment among patients with cirrhosis and infection: a systematic review and meta-analysis (2013)
Journal Article
(2013). Albumin reduces paracentesis induced circulatory dysfunction and reduces death and renal impairment among patients with cirrhosis and infection: a systematic review and meta-analysis. BioMed Research International, https://doi.org/10.1155/2013/295153

Background. Studies have suggested that albumin has a value in cirrhotic patients undergoing paracentesis but its value in infection and sepsis is less clear. We planned to perform a meta-analysis of the risk of adverse outcomes in cirrhotic patients... Read More about Albumin reduces paracentesis induced circulatory dysfunction and reduces death and renal impairment among patients with cirrhosis and infection: a systematic review and meta-analysis.

Fibrin-based scaffold incorporating VEGF- and bFGF-loaded nanoparticles stimulates wound healing in diabetic mice. (2013)
Journal Article
(2013). Fibrin-based scaffold incorporating VEGF- and bFGF-loaded nanoparticles stimulates wound healing in diabetic mice. Acta biomaterialia, 7814 -7821

Diabetic skin ulcers are difficult to heal spontaneously due to the reduced levels and activity of endogenous growth factors. Recombinant human vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) are known to stimulate... Read More about Fibrin-based scaffold incorporating VEGF- and bFGF-loaded nanoparticles stimulates wound healing in diabetic mice..

Enhanced nanomagnetic gene transfection of human prenatal cardiac progenitor cells and adult cardiomyocytes (2013)
Journal Article
(2013). Enhanced nanomagnetic gene transfection of human prenatal cardiac progenitor cells and adult cardiomyocytes. PloS one, e69812 - ?. https://doi.org/10.1371/journal.pone.0069812

Magnetic nanoparticle-based gene transfection has been shown to be an effective, non-viral technique for delivery of both plasmid DNA and siRNA into cells in culture. It has several advantages over other non-viral delivery techniques, such as short t... Read More about Enhanced nanomagnetic gene transfection of human prenatal cardiac progenitor cells and adult cardiomyocytes.

Valproate reduces collagen and osteonectin in cultured bone cells (2013)
Journal Article
Humphrey, E. L., Morris, G. E., & Fuller, H. R. (2013). Valproate reduces collagen and osteonectin in cultured bone cells. Epilepsy Research, 106(3), 446-450. https://doi.org/10.1016/j.eplepsyres.2013.06.011

Valproate is a histone deacetylase (HDAC) inhibitor that was introduced more than 40 years ago and is commonly used to treat epilepsy and mood disorders. Its long-term side effects can include bone loss, although the exact mechanism for this is curre... Read More about Valproate reduces collagen and osteonectin in cultured bone cells.

The Contributions of the Celtic Masters and Their Associates (2013)
Journal Article
Moss, G. (2013). The Contributions of the Celtic Masters and Their Associates. Skin Pharmacology and Physiology, 26(4-6), 343-355. https://doi.org/10.1159/000352012

This article summarizes the work of 4 researchers in the field of percutaneous absorption - Keith Brain, Mark Cronin, Dermot McCafferty and John Pugh. It summarizes their main achievements in this field and reviews their major contributions to the br... Read More about The Contributions of the Celtic Masters and Their Associates.

Cardiac rehabilitation: impact of graded exercise in the recovery period following myocardial infarction (2013)
Journal Article
White, S. (in press). Cardiac rehabilitation: impact of graded exercise in the recovery period following myocardial infarction. Research Reports in Clinical Cardiology, 2013(4), 115-124. https://doi.org/10.2147/rrcc.s30955

This paper reviews the impact of graded exercise undertaken as part of a cardiac rehabilitation (CR) program in the recovery period following a myocardial infarction, focusing on how CR may be best provided and the evidence-base relating to exercise-... Read More about Cardiac rehabilitation: impact of graded exercise in the recovery period following myocardial infarction.

A multidirectional fracture stiffness model to determine the principal stiffness properties of a healing human tibia (2013)
Journal Article
Ogrodnik, P. J., Thomas, P. B., Moorcroft, C. I., & Mohammed, K. N. (2013). A multidirectional fracture stiffness model to determine the principal stiffness properties of a healing human tibia. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 227(10), 1125-1134. https://doi.org/10.1177/0954411913495789

A model for the stiffness of a fractured human tibia has been developed. The model is based on Mohr’s circle of inertia and relies on tibial fracture stiffness being measured in a number of planes. Using in vitro data, it has been shown that this mod... Read More about A multidirectional fracture stiffness model to determine the principal stiffness properties of a healing human tibia.

An educational framework for managing and supporting medication adherence in Europe (2013)
Journal Article
White, S., Clyne, W., & Mshelia, C. (2013). An educational framework for managing and supporting medication adherence in Europe. Pharmacy Education, 13, 118-120

Introduction: Decisions about taking medicines ultimately lie with patients, so health professionals need to engage with patients to manage and support medication adherence. Health professionals need appropriate education to do this. We aimed to deve... Read More about An educational framework for managing and supporting medication adherence in Europe.

Chronic disease multimorbidity transitions across healthcare interfaces and associated costs: a clinical-linkage database study. (2013)
Journal Article
(2013). Chronic disease multimorbidity transitions across healthcare interfaces and associated costs: a clinical-linkage database study. BMJ Open, https://doi.org/10.1136/bmjopen-2013-003109

OBJECTIVE: To investigate multimorbidity transitions from general practice populations across healthcare interfaces and the associated healthcare costs. DESIGN: Clinical-linkage database study. SETTING: Population (N=60 660) aged 40 years and over re... Read More about Chronic disease multimorbidity transitions across healthcare interfaces and associated costs: a clinical-linkage database study..