Outputs (158)

Human mesenchymal stem cells stimulate EaHy926 endothelial cell migration: combined proteomic and in vitro analysis of the influence of donor-donor variability (2015)
Journal Article
Walter, M., Kohli, N., Major, T., Fuller, H., Wright, K., Kuiper, J., & Johnson, W. (2015). Human mesenchymal stem cells stimulate EaHy926 endothelial cell migration: combined proteomic and in vitro analysis of the influence of donor-donor variability. Journal of Stem Cells and Regenerative Medicine, 11(1), 18-24. https://doi.org/10.46582/jsrm.1101004

Mesenchymal stem cells (MSCs) stimulate angiogenesis within a wound environment and this effect is mediated through paracrine interactions with the endothelial cells present. Here we report that human MSC-conditioned medium (n=3 donors) significantly... Read More about Human mesenchymal stem cells stimulate EaHy926 endothelial cell migration: combined proteomic and in vitro analysis of the influence of donor-donor variability.

Measurement of C-reactive protein, procalcitonin and neutrophil elastase in saliva of COPD patients and healthy controls: correlation to self-reported wellbeing parameters (2015)
Journal Article
Patel, N., Belcher, J., Thorpe, G., Forsyth, N. R., & Spiteri, M. A. (2015). Measurement of C-reactive protein, procalcitonin and neutrophil elastase in saliva of COPD patients and healthy controls: correlation to self-reported wellbeing parameters. Respiratory Research, 16, Article 62. https://doi.org/10.1186/s12931-015-0219-1

BACKGROUND: Saliva is increasingly promoted as an alternative diagnostic bio-sample to blood; however its role in respiratory disease requires elucidation. Our aim was to investigate whether C-reactive protein (CRP), procalcitonin (PCT) and neutrophi... Read More about Measurement of C-reactive protein, procalcitonin and neutrophil elastase in saliva of COPD patients and healthy controls: correlation to self-reported wellbeing parameters.

The cemented twin-peg Oxford partial knee replacement survivorship: a cohort study (2015)
Journal Article
Kuiper. (2015). The cemented twin-peg Oxford partial knee replacement survivorship: a cohort study. https://doi.org/10.1016/j.knee.2015.03.011

Background A new twin-peg version of the Oxford knee was introduced in 2003. However, until now there has been no information about its survivorship. The aim of this study was to determine the survivorship, and the patients' perception of outcome ov... Read More about The cemented twin-peg Oxford partial knee replacement survivorship: a cohort study.

ADAMTS-4 activity in synovial fluid as a biomarker of inflammation and effusion (2015)
Journal Article
Roberts, S., Evans, H., Wright, K., van Niekerk, L., Caterson, B., Richardson, J., …Kuiper, J. (2015). ADAMTS-4 activity in synovial fluid as a biomarker of inflammation and effusion. Osteoarthritis and Cartilage, 23(9), 1622-1626. https://doi.org/10.1016/j.joca.2015.05.006

Objective To evaluate the potential of ADAMTS-4 (aggrecanase -1) activity in synovial fluid (SF) as a biomarker of knee injury and joint disease. Design We have measured ADAMTS-4 activity in the synovial fluid of 170 orthopaedic patients with di... Read More about ADAMTS-4 activity in synovial fluid as a biomarker of inflammation and effusion.

Preparing to prescribe: how do clerkship students learn in the midst of complexity? (2015)
Journal Article
(2015). Preparing to prescribe: how do clerkship students learn in the midst of complexity?. Advances in Health Sciences Education, 1339-1354. https://doi.org/10.1007/s10459-015-9606-0

Prescribing tasks, which involve pharmacological knowledge, clinical decision-making and practical skill, take place within unpredictable social environments and involve interactions within and between endlessly changing health care teams. Despite th... Read More about Preparing to prescribe: how do clerkship students learn in the midst of complexity?.

Promotion of EGF receptor signaling improves the quality of low developmental competence oocytes (2015)
Journal Article
Sugimura, S., Ritter, L. J., Rose, R. D., Thompson, J. G., Smitz, J., Mottershead, D. G., & Gilchrist, R. B. (2015). Promotion of EGF receptor signaling improves the quality of low developmental competence oocytes. Developmental Biology, 403(2), 139-149. https://doi.org/10.1016/j.ydbio.2015.05.008

Oocytes acquire developmental competence with progressive folliculogenesis. Cumulus oocyte complexes (COCs) from small antral follicles have inherent low competence and are poorly responsive to amphiregulin (AREG) which normally mediates oocyte matur... Read More about Promotion of EGF receptor signaling improves the quality of low developmental competence oocytes.

Prevalence and Impact of Co-morbidity Burden as Defined by the Charlson Co-morbidity Index on 30-Day and 1- and 5-Year Outcomes After Coronary Stent Implantation (from the Nobori-2 Study). (2015)
Journal Article
Mamas. (2015). Prevalence and Impact of Co-morbidity Burden as Defined by the Charlson Co-morbidity Index on 30-Day and 1- and 5-Year Outcomes After Coronary Stent Implantation (from the Nobori-2 Study). American Journal of Cardiology, 364-371. https://doi.org/10.1016/j.amjcard.2015.04.047

Early diagnosis of cardiac implantable electronic device generator pocket infection using 18F-FDG-PET/CT (2015)
Journal Article
Mamas. (2015). Early diagnosis of cardiac implantable electronic device generator pocket infection using 18F-FDG-PET/CT. European Heart Journal - Cardiovascular Imaging, 521 - 530. https://doi.org/10.1093/ehjci/jeu295

AIMS: To examine the utility of (18)F-fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET/CT) in the early diagnosis of cardiac implantable electronic device (CIED) generator pocket infection. METHODS AND RESULTS: A tot... Read More about Early diagnosis of cardiac implantable electronic device generator pocket infection using 18F-FDG-PET/CT.

Deploying clinical grade magnetic nanoparticles with magnetic fields to magnetolabel neural stem cells in adherent versus suspension cultures (2015)
Journal Article
Weinberg, D., Adams, C., & Chari, D. (2015). Deploying clinical grade magnetic nanoparticles with magnetic fields to magnetolabel neural stem cells in adherent versus suspension cultures. RSC advances, 5, 43353-43360. https://doi.org/10.1039/c5ra07481a

Neural stem cells (NSCs) have a high therapeutic potential for patients with neurological disease/injury given their neuroregenerative and immunomodulatory capabilities. In recent years, magnetic nanoparticles (MNPs) have been used as contrast agents... Read More about Deploying clinical grade magnetic nanoparticles with magnetic fields to magnetolabel neural stem cells in adherent versus suspension cultures.

Release of toxic ammonia and volatile organic compounds by heated cannabis and their relation to tetrahydrocannabinol content (2015)
Journal Article
(2015). Release of toxic ammonia and volatile organic compounds by heated cannabis and their relation to tetrahydrocannabinol content. Analytical Methods, 4104 - 4110. https://doi.org/10.1039/C5AY00593K

Studies have been carried out of the compounds generated from heated “street” cannabis in the commercial device known as the “Volcano” using the selected ion flow tube mass spectrometry (SIFT-MS) analytical method. Such vaporising devices are preferr... Read More about Release of toxic ammonia and volatile organic compounds by heated cannabis and their relation to tetrahydrocannabinol content.