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Online induction programme with webinar: a case study (2015)
Journal Article
Warren, S., Black, P., & Mills, E. (2015). Online induction programme with webinar: a case study. Journal of Applied Research in Higher Education, 7(1), 123-132. https://doi.org/10.1108/jarhe-02-2014-0019

Purpose The purpose of this paper is to describe the introduction of an online induction programme including an interactive webinar on a distance learning course and to present student feedback on the programme. It focuses on lessons learnt and impl... Read More about Online induction programme with webinar: a case study.

Interactions of antiretroviral drugs with the SLC22A1 (OCT1) drug transporter (2015)
Journal Article
(2015). Interactions of antiretroviral drugs with the SLC22A1 (OCT1) drug transporter. Frontiers in Pharmacology, https://doi.org/10.3389/fphar.2015.00078

The SLC22A1 influx transporter is expressed on the basolateral membrane of hepatocytes and is involved in the excretion of numerous cations. Inhibition of SLC22A1 by several antiretrovirals, such as the protease inhibitor darunavir, has not previousl... Read More about Interactions of antiretroviral drugs with the SLC22A1 (OCT1) drug transporter.

Effect of journal out-of-roundness on stability of a symmetric hydrodynamic journal bearing system. Part 1: Theoretical analysis (2015)
Journal Article
Xu, W., Ogrodnik, P., Li, B., Zhang, H., & Gao, S. (2015). Effect of journal out-of-roundness on stability of a symmetric hydrodynamic journal bearing system. Part 1: Theoretical analysis. Proceedings of the Institution of Mechanical Engineers, Part J: Journal of Engineering Tribology, 229(11), 1347-1358. https://doi.org/10.1177/1350650115579211

The study examines the effect of journal out-of-roundness on the dynamic performance of rotating machines supported by oil film bearings. A general model of a symmetric hydrodynamic journal bearing system allowing for journal out-of-roundness is pres... Read More about Effect of journal out-of-roundness on stability of a symmetric hydrodynamic journal bearing system. Part 1: Theoretical analysis.

Effect of journal out-of-roundness on stability of a symmetric hydrodynamic journal bearing system. Part 2: Experimental investigation (2015)
Journal Article
Xu, W., Ogrodnik, P. J., Li, B., Zhang, H., & Gao, S. (2015). Effect of journal out-of-roundness on stability of a symmetric hydrodynamic journal bearing system. Part 2: Experimental investigation. Proceedings of the Institution of Mechanical Engineers, Part J: Journal of Engineering Tribology, 229(11), 1359-1371. https://doi.org/10.1177/1350650115579677

Part 2 of the study furthers the research and aims to present evidences from an experimental investigation. The work presents the experimental research with a rig for examining the effect of journal out-of-roundness on the dynamic performance of a sy... Read More about Effect of journal out-of-roundness on stability of a symmetric hydrodynamic journal bearing system. Part 2: Experimental investigation.

Discovery of a series of 2-(pyridinyl) pyrimidines as potent antagonists of GPR40 (2015)
Journal Article
Waring, M. J., Baker, D. J., Bennett, S. N., Dossetter, A. G., Fenwick, M., Garcia, R., …Wilkinson, G. (2015). Discovery of a series of 2-(pyridinyl) pyrimidines as potent antagonists of GPR40. MedChemComm, 2015(6), 1024-1029. https://doi.org/10.1039/C5MD00037H

A series of 2-(pyridinyl)pyrimidines were identified as potent GPR40 antagonists. Despite significant challenges related to improving the combination of potency and lipophilicity within the series, the compounds were optimised to identify a suitable... Read More about Discovery of a series of 2-(pyridinyl) pyrimidines as potent antagonists of GPR40.

The role of parvovirus B19 and the immune response in the pathogenesis of acute leukemia (2015)
Journal Article
(2015). The role of parvovirus B19 and the immune response in the pathogenesis of acute leukemia. Reviews in Medical Virology, https://doi.org/10.1002/rmv.1830

In this article, we review the evidence suggesting a possible role for B19 virus in the pathogenesis of a subset of cases of acute leukemia. Human parvovirus B19 infection may complicate the clinical course of patients with acute leukemia and may als... Read More about The role of parvovirus B19 and the immune response in the pathogenesis of acute leukemia.

Pitfalls in the analysis of volatile breath biomarkers: suggested solutions and SIFT-MS quantification of single metabolites (2015)
Journal Article
(2015). Pitfalls in the analysis of volatile breath biomarkers: suggested solutions and SIFT-MS quantification of single metabolites. Journal of Breath Research, 022001 -?. https://doi.org/10.1088/1752-7155/9/2/022001

The experimental challenges presented by the analysis of trace volatile organic compounds (VOCs) in exhaled breath with the objective of identifying reliable biomarkers are brought into focus. It is stressed that positive identification and accurate... Read More about Pitfalls in the analysis of volatile breath biomarkers: suggested solutions and SIFT-MS quantification of single metabolites.

BMP2 repression and optimized culture conditions promote human bone marrow-derived mesenchymal stem cell isolation. (2015)
Journal Article
Gawain Kay, A., Dale, T., Mehedi Akram, K., Mohan, P., Hampson, K., Maffulli, N., …Forsyth, N. (2015). BMP2 repression and optimized culture conditions promote human bone marrow-derived mesenchymal stem cell isolation. Regenerative Medicine, 10(2), 109 - 125. https://doi.org/10.2217/rme.14.67

AIM: Human mesenchymal stem cells (hMSC) are multipotent progenitor cells. We propose the optimization of hMSC isolation and recovery using the application of a controlled hypoxic environment. MATERIALS & METHODS: We evaluated oxygen, glucose and ser... Read More about BMP2 repression and optimized culture conditions promote human bone marrow-derived mesenchymal stem cell isolation..

Remote activation of the Wnt/ß-catenin signalling pathway using functionalised magnetic particles. (2015)
Journal Article
(2015). Remote activation of the Wnt/ß-catenin signalling pathway using functionalised magnetic particles. PloS one, e0121761 - ?. https://doi.org/10.1371/journal.pone.0121761

Wnt signalling pathways play crucial roles in developmental biology, stem cell fate and tissue patterning and have become an attractive therapeutic target in the fields of tissue engineering and regenerative medicine. Wnt signalling has also been sho... Read More about Remote activation of the Wnt/ß-catenin signalling pathway using functionalised magnetic particles..