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Outputs (158)

Studies on the Pd-catalyzed dimerization of silacyclobutanes (2015)
Journal Article
Aborways, M., & Moran, W. (2015). Studies on the Pd-catalyzed dimerization of silacyclobutanes. Journal of Organometallic Chemistry, 797, 57-59. https://doi.org/10.1016/j.jorganchem.2015.07.040

Dimerization of silacyclobutanes has been achieved under palladium catalysis at room temperature. A previous report described the requirement for high temperature and a stoichiometric amount of palladium complex to effect this process.

Longevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intake (2015)
Journal Article
(2015). Longevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intake. Aging cell, 511 - 523. https://doi.org/10.1111/acel.12342

Advancing age is associated with a progressive loss of skeletal muscle (SkM) mass and function. Given the worldwide aging demographics, this is a major contributor to morbidity, escalating socio-economic costs and ultimately mortality. Previously, it... Read More about Longevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intake.

Freezeout concept and dynamical transport model in intermediate-energy heavy-ion reactions (2015)
Journal Article
Liu, X., Lin, W., Huang, M., Wada, R., Wang, J., Chen, Z., …Hu, Q. Freezeout concept and dynamical transport model in intermediate-energy heavy-ion reactions. Physical Review C - Nuclear Physics, 92(1), https://doi.org/10.1103/physrevc.92.014623

For the central collision events of 40Ca+40Ca, generated by an antisymmetrized molecular dynamics model in the intermediate energy range of 35 to 300 MeV/nucleon, the density and temperature of a fragmenting source have been extracted using a self-co... Read More about Freezeout concept and dynamical transport model in intermediate-energy heavy-ion reactions.

Is alcohol consumption in older adults associated with poor self-rated health? Cross-sectional and longitudinal analyses from the English Longitudinal Study of Ageing (2015)
Journal Article
Frisher, M., Mendonça, M., Shelton, N., Pikhart, H., de Oliveira, C., & Holdsworth, C. (2015). Is alcohol consumption in older adults associated with poor self-rated health? Cross-sectional and longitudinal analyses from the English Longitudinal Study of Ageing. BMC Public Health, https://doi.org/10.1186/s12889-015-1993-x

Background Increases in alcohol related mortality and morbidity have been reported among older people in England over the last decade. There is, however, evidence that drinking is protective for some health conditions. The validity of this evidence... Read More about Is alcohol consumption in older adults associated with poor self-rated health? Cross-sectional and longitudinal analyses from the English Longitudinal Study of Ageing.

Potential use of hybrid iron oxide gold nanoparticles as drug carriers (2015)
Book Chapter
Curtis, A., & Hoskins, C. Potential use of hybrid iron oxide gold nanoparticles as drug carriers. In Nano Based Drug Delivery (535-546). IAPC Publishing (International Association of Physical Chemists). https://doi.org/10.5599/obp.8.21

Hybrid nanoparticles are composed of more than one material fused together to increase functionality. These often consist of polymers coated onto the surface of metallic nanoparticles to render them useful in biomedicine [1,2]. In this chapter the te... Read More about Potential use of hybrid iron oxide gold nanoparticles as drug carriers.

Immortalisation with hTERT Impacts on Sulphated Glycosaminoglycan Secretion and Immunophenotype in a Variable and Cell Specific Manner (2015)
Journal Article
Dale, T. P., de Castro, A., Kuiper, N. J., Parkinson, E. K., & Forsyth, N. R. (2015). Immortalisation with hTERT Impacts on Sulphated Glycosaminoglycan Secretion and Immunophenotype in a Variable and Cell Specific Manner. PloS one, 10(7), Article e0133745. https://doi.org/10.1371/journal.pone.0133745

BACKGROUND: Limited options for the treatment of cartilage damage have driven the development of tissue engineered or cell therapy alternatives reliant on ex vivo cell expansion. The study of chondrogenesis in primary cells is difficult due to progre... Read More about Immortalisation with hTERT Impacts on Sulphated Glycosaminoglycan Secretion and Immunophenotype in a Variable and Cell Specific Manner.

Immortalisation with hTERT Impacts on Sulphated Glycosaminoglycan Secretion and Immunophenotype in a Variable and Cell Specific Manner. (2015)
Journal Article
Dale, T. P., de Castro, A., Kuiper, N. J., Parkinson, E. K., & Forsyth, N. R. (2015). Immortalisation with hTERT Impacts on Sulphated Glycosaminoglycan Secretion and Immunophenotype in a Variable and Cell Specific Manner. PloS one, 10(7), Article e0133745. https://doi.org/10.1371/journal.pone.0133745

BACKGROUND: Limited options for the treatment of cartilage damage have driven the development of tissue engineered or cell therapy alternatives reliant on ex vivo cell expansion. The study of chondrogenesis in primary cells is difficult due to progre... Read More about Immortalisation with hTERT Impacts on Sulphated Glycosaminoglycan Secretion and Immunophenotype in a Variable and Cell Specific Manner..

Introduction (2015)
Book Chapter
Moss, G. P. (2015). Introduction. In Novel Delivery Systems for Transdermal and Intradermal Drug Delivery (1-40). Wiley. https://doi.org/10.1002/9781118734506.ch1

This chapter describes the physiology and structure of the skin, emphasising and focusing on the skin's main barrier to permeation – the stratum corneum – and how its structure and nature, compared to other regions and layers of the skin, results in... Read More about Introduction.

Problems with oral formulations prescribed to children: a focus group study of healthcare professionals (2015)
Journal Article
Venables. (2015). Problems with oral formulations prescribed to children: a focus group study of healthcare professionals. International Journal of Clinical Pharmacy, 1057-1067. https://doi.org/10.1007/s11096-015-0152-x

Background There is evidence to suggest that adherence with prescribed medication is lower amongst adolescents and children than in adults. Medication adherence rates between 11 and 93 % in paediatric patients have been reported. More research needs... Read More about Problems with oral formulations prescribed to children: a focus group study of healthcare professionals.