Skip to main content

Research Repository

Advanced Search

Outputs (243)

Mesenchymal stem cell derived products attenuate cytokine-induced apoptosis in pancreatic beta cells (2016)
Presentation / Conference
Al Azzawi, B., Merkhan, M. M., Kelly, C., & Forsyth, N. (2016, March). Mesenchymal stem cell derived products attenuate cytokine-induced apoptosis in pancreatic beta cells. Poster presented at Abstracts of the Diabetes UK Professional Conference 2016, Scottish Exhibition and Conference Centre, Glasgow, Scotland

Aims:Cytokine-driven beta cell apoptosis is central to Type 1diabetes. Mesenchymal stem cells (MSCs) are multipotent cellswith significant immunomodulatory capacity, which counteractautoimmunityand enhance islet engraftment and survival. The aimof th... Read More about Mesenchymal stem cell derived products attenuate cytokine-induced apoptosis in pancreatic beta cells.

EAHP European Statements baseline survey 2015: results (2016)
Journal Article
(2016). EAHP European Statements baseline survey 2015: results. European Journal of Hospital Pharmacy, 69 - 75. https://doi.org/10.1136/ejhpharm-2016-000889

Objectives The European Statements baseline survey was designed to give an insight to how well the European Statements of Hospital Pharmacy (the Statements) are being implemented and to help inform the European Association of Hospital Pharmacists (EA... Read More about EAHP European Statements baseline survey 2015: results.

Alternative tension band technique for olecranon fractures: A biomechanical study (2016)
Journal Article
Singh, S., Kuiper, J., Behzadian, A., Madhusudhan, T., & Sinha, A. (2016). Alternative tension band technique for olecranon fractures: A biomechanical study. Injury, 47(2), 294-295. https://doi.org/10.1016/j.injury.2015.12.008

Objectives: To investigate whether an alternative tension band wire technique will produce greater compression and less displacement at olecranon (elbow) fracture sites compared to a standard figure of eight tension band technique. Olecranon fracture... Read More about Alternative tension band technique for olecranon fractures: A biomechanical study.

Modelling conditions and health care processes in electronic health records: an application to severe mental illness with the clinical practice research datalink (2016)
Journal Article
(2016). Modelling conditions and health care processes in electronic health records: an application to severe mental illness with the clinical practice research datalink. PloS one, https://doi.org/10.1371/journal.pone.0146715

Background The use of Electronic Health Records databases for medical research has become mainstream. In the UK, increasing use of Primary Care Databases is largely driven by almost complete computerisation and uniform standards within the National... Read More about Modelling conditions and health care processes in electronic health records: an application to severe mental illness with the clinical practice research datalink.

EAHP European Statements baseline survey 2015: first steps on the implementation journey (2016)
Journal Article
(2016). EAHP European Statements baseline survey 2015: first steps on the implementation journey. European Journal of Hospital Pharmacy, 76 -79. https://doi.org/10.1136/ejhpharm-2016-000892

An implementation plan was developed in conjunction with the publication of the European Statements of Hospital Pharmacy. Subsequently a baseline survey on the status of the Statements was conducted with specific questions on awareness, capability an... Read More about EAHP European Statements baseline survey 2015: first steps on the implementation journey.

EAHP European Statements baseline survey 2015: methodology (2016)
Journal Article
(2016). EAHP European Statements baseline survey 2015: methodology. European Journal of Hospital Pharmacy, 65 -68. https://doi.org/10.1136/ejhpharm-2016-000893

The European Statements of Hospital Pharmacy are a set of hospital pharmacy practice standards published by the European Association of Hospital Pharmacists (EAHP) for European health systems to ensure safe, effective and optimal use of medicines in... Read More about EAHP European Statements baseline survey 2015: methodology.

Automated Electrophysiological and Pharmacological Evaluation of Human Pluripotent Stem Cell-Derived Cardiomyocytes (2016)
Journal Article
Rajamohan, D., Kalra, S., Duc Hoang, M., George, V., Staniforth, A., Russell, H., …Denning, C. (2016). Automated Electrophysiological and Pharmacological Evaluation of Human Pluripotent Stem Cell-Derived Cardiomyocytes. Stem Cells and Development, 25(6), 439-452. https://doi.org/10.1089/scd.2015.0253

Automated planar patch clamp systems are widely used in drug evaluation studies because of their ability to provide accurate, reliable, and reproducible data in a high-throughput manner. Typically, CHO and HEK tumorigenic cell lines overexpressing si... Read More about Automated Electrophysiological and Pharmacological Evaluation of Human Pluripotent Stem Cell-Derived Cardiomyocytes.

A Tailor-Made Synthetic Polymer for Cell Encapsulation: Design Rationale, Synthesis, Chemical-Physics and Biological Characterizations (2016)
Journal Article
Gerges, I., Tamplenizza, M., Rossi, E., Tocchio, A., Martello, F., Recordati, C., …Lenardi, C. (2016). A Tailor-Made Synthetic Polymer for Cell Encapsulation: Design Rationale, Synthesis, Chemical-Physics and Biological Characterizations. Macromolecular Bioscience, 16(6), 870-881. https://doi.org/10.1002/mabi.201500386

This study presents a custom-made in situ gelling polymeric precursor for cell encapsulation. Composed of poly((2-hydroxyethyl)methacrylate-co-(3-aminopropyl)methacrylamide) (P(HEMA-co-APM) mother backbone and RGD-mimicking poly(amidoamine) (PAA) moi... Read More about A Tailor-Made Synthetic Polymer for Cell Encapsulation: Design Rationale, Synthesis, Chemical-Physics and Biological Characterizations.

Abstract P4-10-14: Breast reconstruction changes coping mechanisms in breast cancer survivorship (2016)
Journal Article
Lake, B., Fuller, H., Rastall, S., & Usman, T. (2016). Abstract P4-10-14: Breast reconstruction changes coping mechanisms in breast cancer survivorship. Cancer Research, 76(4_Supplement), P4-10-14-P4-10-14. https://doi.org/10.1158/1538-7445.sabcs15-p4-10-14

Introduction Cancer survivorship is the process of living through and beyond cancer; a key part is how a patient copes with their diagnosis. Breast cancer is the most common malignancy of women worldwide and is known to be a severe stressor. Resea... Read More about Abstract P4-10-14: Breast reconstruction changes coping mechanisms in breast cancer survivorship.