Outputs (186)

Codelivery of anti-cancer agents via double-walled polymeric microparticles/injectable hydrogel: A promising approach for treatment of triple negative breast cancer (2017)
Journal Article
Davoodi, P., Ng, W. C., Srinivasan, M. P., & Wang, C. (2017). Codelivery of anti-cancer agents via double-walled polymeric microparticles/injectable hydrogel: A promising approach for treatment of triple negative breast cancer. Biotechnology and Bioengineering, 114(12), 2931-2946. https://doi.org/10.1002/bit.26406

Triple negative breast cancer (TNBC) is an aggressive sub-type of breast cancer that rarely responds to conventional chemotherapy. Therefore, novel agents or new routes need to be developed to improve treatment efficacy and diminish severe side-effec... Read More about Codelivery of anti-cancer agents via double-walled polymeric microparticles/injectable hydrogel: A promising approach for treatment of triple negative breast cancer.

Skin advanced glycation content reflects vaginal tissue glycation level in relation to pregnancy (2017)
Journal Article
Yang. (2017). Skin advanced glycation content reflects vaginal tissue glycation level in relation to pregnancy. Medical Hypotheses, https://doi.org/10.1016/j.mehy.2017.09.016

Abstract A few studies have revealed that the advanced glycation content of the vaginal wall in pelvic organ prolapse tissues is elevated. This elevation makes advanced glycation a significant association with the disease. Early detection of vaginal... Read More about Skin advanced glycation content reflects vaginal tissue glycation level in relation to pregnancy.

The Talke of the Towne: News, Crime and the Public Sphere in Seven (2017)
Journal Article
(2017). The Talke of the Towne: News, Crime and the Public Sphere in Seven. Cultural and Social History, https://doi.org/10.1080/14780038.2017.1375703

This article reconsiders ideas of the public sphere in the seventeenth century, by focusing on how public opinion is shaped by the movement o information between media and between receivers. It contends that the scholarly preoccupation with a public... Read More about The Talke of the Towne: News, Crime and the Public Sphere in Seven.

Testosterone replacement therapy: improved sexual desire and erectile function in men with type 2 diabetes following a 30-week randomized placebo-controlled study. (2017)
Journal Article
(2017). Testosterone replacement therapy: improved sexual desire and erectile function in men with type 2 diabetes following a 30-week randomized placebo-controlled study. Andrology, 905 - 913. https://doi.org/10.1111/andr.12399

Although testosterone replacement treatment (TRT) can improve sexual function in many hypogonadal (HG) men with type 2 diabetes (T2DM), some show either no improvement or only in a limited number of domains. Indeed, it is often difficult for the clin... Read More about Testosterone replacement therapy: improved sexual desire and erectile function in men with type 2 diabetes following a 30-week randomized placebo-controlled study..

Nanoscale correlation of iron biochemistry with amyloid plaque morphology in Alzheimer’s disease transgenic mouse cortex (2017)
Journal Article
Telling, N., Everett, J., Collingwood, J. F., Dobson, J., van der Laan, G., Gallagher, J. J., …Hitchcock, A. P. (2017). Nanoscale correlation of iron biochemistry with amyloid plaque morphology in Alzheimer’s disease transgenic mouse cortex. Cell chemical biology, 24(10), 1205-1215. https://doi.org/10.1016/j.chembiol.2017.07.014

A signature characteristic of Alzheimer's disease (AD) is aggregation of amyloid-beta (Aß) fibrils in the brain. Nevertheless, the links between Aß and AD pathology remain incompletely understood. It has been proposed that neurotoxicity arising from... Read More about Nanoscale correlation of iron biochemistry with amyloid plaque morphology in Alzheimer’s disease transgenic mouse cortex.

Iron Biochemistry is Correlated with Amyloid Plaque Morphology in an Established Mouse Model of Alzheimer's Disease. (2017)
Journal Article
Telling, N., Everett, J., Collingwood, J. F., Dobson, J., van der Laan, G., Gallagher, J. J., …Hitchcock, A. P. (2017). Iron Biochemistry is Correlated with Amyloid Plaque Morphology in an Established Mouse Model of Alzheimer's Disease. Cell chemical biology, 24(10), 1205-1215. https://doi.org/10.1016/j.chembiol.2017.07.014

A signature characteristic of Alzheimer's disease (AD) is aggregation of amyloid-beta (Aß) fibrils in the brain. Nevertheless, the links between Aß and AD pathology remain incompletely understood. It has been proposed that neurotoxicity arising from... Read More about Iron Biochemistry is Correlated with Amyloid Plaque Morphology in an Established Mouse Model of Alzheimer's Disease..

OH defects in quartz as monitor for igneous, metamorphic, and sedimentary processes (2017)
Journal Article
(2017). OH defects in quartz as monitor for igneous, metamorphic, and sedimentary processes. American Mineralogist, 1832 -1842. https://doi.org/10.2138/am-2017-6107

Oriented sections of more than 500 quartz grains from sediments, igneous, and metamorphic rocks from different localities in Sweden, Austria, Germany, and South Africa were analyzed by FTIR spectroscopy, and their OH defect content was determined wit... Read More about OH defects in quartz as monitor for igneous, metamorphic, and sedimentary processes.

Artificial Neural Network Analysis of Volatile Organic Compounds for the detection of lung cancer (2017)
Conference Proceeding
Butcher, J. B., Rutter, A. V., Wootton, A. J., Day, C. R., & Sulé-Suso, J. (2017). Artificial Neural Network Analysis of Volatile Organic Compounds for the detection of lung cancer. In Advances in Computational Intelligence Systems (183-190). https://doi.org/10.1007/978-3-319-66939-7_15

Lung cancer is a widespread disease and it is well understood that systematic, non-invasive and early detection of this progressive and life-threatening disorder is of vital importance for patient outcomes. In this work we present a convergence of fa... Read More about Artificial Neural Network Analysis of Volatile Organic Compounds for the detection of lung cancer.

Anti-influenza activity of diazaadamantanes combined with monoterpene moieties (2017)
Journal Article
Suslov, E., Zarubaev, V. V., Slita, A. V., Ponomarev, K., Korchagina, D., Ayine-Tora, D. M., …Salakhutdinov, N. (2017). Anti-influenza activity of diazaadamantanes combined with monoterpene moieties. Bioorganic and Medicinal Chemistry Letters, 27(19), 4531-4535. https://doi.org/10.1016/j.bmcl.2017.08.062

The antiviral activity of several diaza-adamantanes containing monoterpenoid moieties against a rimantadine-resistant strain of the influenza A/Puerto Rico/8/34 (H1N1) virus was studied. Hetero-adamantanes containing monoterpene moieties at the amina... Read More about Anti-influenza activity of diazaadamantanes combined with monoterpene moieties.

The potential clinical benefits of medicines optimisation through comprehensive geriatric assessment, carried out by secondary care geriatricians, in a general practice care setting in North Staffordshire, UK: a feasibility study. (2017)
Journal Article
(2017). The potential clinical benefits of medicines optimisation through comprehensive geriatric assessment, carried out by secondary care geriatricians, in a general practice care setting in North Staffordshire, UK: a feasibility study. BMJ Open, e015278 - ?. https://doi.org/10.1136/bmjopen-2016-015278

OBJECTIVES: To evaluate the feasibility and potential clinical benefits of medicines optimisation through comprehensive geriatric assessment (CGA) of frail patients with multiple conditions, by secondary care geriatricians in a general practice care... Read More about The potential clinical benefits of medicines optimisation through comprehensive geriatric assessment, carried out by secondary care geriatricians, in a general practice care setting in North Staffordshire, UK: a feasibility study..