Outputs (187)

Point-of-care measurements reveal release of purines into venous blood of stroke patients (2019)
Journal Article
Roffe. (2019). Point-of-care measurements reveal release of purines into venous blood of stroke patients. Purinergic Signalling, 237-246. https://doi.org/10.1007/s11302-019-09647-4

Stroke is a leading cause of death and disability. Here, we examine whether point-of-care measurement of the purines, adenosine, inosine and hypoxanthine, which are downstream metabolites of ATP, has potential to assist the diagnosis of stroke. In a... Read More about Point-of-care measurements reveal release of purines into venous blood of stroke patients.

“Dynamic knee valgus” – are we measuring what we think we’re measuring? An evaluation of static and functional knee calibration methods for application in gait and clinical screening tests of the overhead squat and hurdle step. (2019)
Journal Article
Philp, F., Leboeuf, F., Pandyan, A., & Stewart, C. (2019). “Dynamic knee valgus” – are we measuring what we think we’re measuring? An evaluation of static and functional knee calibration methods for application in gait and clinical screening tests of the overhead squat and hurdle step. Gait and Posture, 70, 298-304. https://doi.org/10.1016/j.gaitpost.2019.03.006

Background
Dynamic “knee valgus” has been identified as a risk factor for significant knee injuries, however, the limits and sources of error associated with existing 3D motion analysis methods have not been well established.

Research question
W... Read More about “Dynamic knee valgus” – are we measuring what we think we’re measuring? An evaluation of static and functional knee calibration methods for application in gait and clinical screening tests of the overhead squat and hurdle step..

Remote manipulation of magnetic nanoparticles using magnetic field gradient to promote cancer cell death (2019)
Journal Article
Lim, J., Dobson, J., Subramanian, M., Miaskowski, A., & Jenkins, S. (2019). Remote manipulation of magnetic nanoparticles using magnetic field gradient to promote cancer cell death. Applied Physics A, https://doi.org/10.1007/s00339-019-2510-3

The manipulation of magnetic nanoparticles (MNPs) using an external magnetic field, has been successfully demonstrated in various biomedical applications. Some have utilised this non-invasive external stimulus and there is an potential to build on th... Read More about Remote manipulation of magnetic nanoparticles using magnetic field gradient to promote cancer cell death.

Low failure rate at short term for 40?mm heads and second generation triple annealed HCLPE liners in hybrid Hip Replacements (2019)
Journal Article
Kuiper. (2019). Low failure rate at short term for 40?mm heads and second generation triple annealed HCLPE liners in hybrid Hip Replacements. Journal of Clinical Orthopaedics and Trauma, 350-357. https://doi.org/10.1016/j.jcot.2017.12.008

Introduction
40?mm large diameter heads offer the advantages of lesser dislocation rates and better stability while highly cross linked polyethylene have lower wear rates than ultra high molecular weight polyethylene. Studies of the survivorship of... Read More about Low failure rate at short term for 40?mm heads and second generation triple annealed HCLPE liners in hybrid Hip Replacements.

Low failure rate at short term for 40?mm heads and second generation triple annealed HCLPE liners in hybrid Hip Replacements (2019)
Journal Article
(2019). Low failure rate at short term for 40?mm heads and second generation triple annealed HCLPE liners in hybrid Hip Replacements. Journal of Clinical Orthopaedics and Trauma, 350-357. https://doi.org/10.1016/j.jcot.2017.12.008

PCSK9 Inhibitors in Diabetic Dyslipidemia (2019)
Book Chapter
(2019). PCSK9 Inhibitors in Diabetic Dyslipidemia. In RSSDI Diabetes Update 2018 (374-378). https://doi.org/10.5005/jp/books/18092_77

The association between cardiovascular disease (CVD) risk and raised serum total cholesterol (TC) and low density lipoprotein-cholesterol (LDL-C) has been demonstrated in epidemiology1 and intervention trials showing significant decreases in CVD foll... Read More about PCSK9 Inhibitors in Diabetic Dyslipidemia.

Estimating risk of encapsulating peritoneal sclerosis accounting for the competing risk of death (2019)
Journal Article
Lambie, M., Teece, L., Johnson, D. W., Petrie, M., Mactier, R., Solis-Trapala, I., …Davies, S. J. (2019). Estimating risk of encapsulating peritoneal sclerosis accounting for the competing risk of death. Nephrology Dialysis Transplantation, 1585-1591. https://doi.org/10.1093/ndt/gfz034

Background
Risk of Encapsulating Peritoneal Sclerosis (EPS) is strongly associated with the duration of peritoneal dialysis (PD), such that patients who have been on PD for some time may consider elective transfer to haemodialysis to mitigate risk o... Read More about Estimating risk of encapsulating peritoneal sclerosis accounting for the competing risk of death.

Mauritian Endemic Medicinal Plant Extracts Induce G2/M Phase Cell Cycle Arrest and Growth Inhibition of Oesophageal Squamous Cell Carcinoma in Vitro (2019)
Journal Article
Rummun, N., Hughes, R., Beesoo, R., Li, W., Aldulaimi, O., Macleod, K., …Neergheen-Bhujun, V. (2019). Mauritian Endemic Medicinal Plant Extracts Induce G2/M Phase Cell Cycle Arrest and Growth Inhibition of Oesophageal Squamous Cell Carcinoma in Vitro

Terrestrial plants have contributed massively to the development of modern oncologic drugs. Despite the wide acceptance of Mauritian endemic flowering plants in traditional medicine, scientific evidence of their chemotherapeutic potential is lacking.... Read More about Mauritian Endemic Medicinal Plant Extracts Induce G2/M Phase Cell Cycle Arrest and Growth Inhibition of Oesophageal Squamous Cell Carcinoma in Vitro.

Striking lung cancer response to self-administration of cannabidiol: a case report and literature review (2019)
Journal Article
Sule-Suso, J., Watson, N., van Pittius, D., & Jegannathen, A. (2019). Striking lung cancer response to self-administration of cannabidiol: a case report and literature review. SAGE Open Medical Case Reports, https://doi.org/10.1177/2050313X19832160

In spite of new drugs, lung cancer is associated with a very poor prognosis. Whilst targeted therapies are improving outcomes, it is not uncommon for many patients to have only a partial response, and relapse during follow up. Thus, new drugs or re-e... Read More about Striking lung cancer response to self-administration of cannabidiol: a case report and literature review.

International Variations in Peritoneal Dialysis Utilization and Implications for Practice (2019)
Journal Article
Davies. (2019). International Variations in Peritoneal Dialysis Utilization and Implications for Practice. American Journal of Kidney Diseases, https://doi.org/10.1053/j.ajkd.2018.12.033

In many countries, the use of peritoneal dialysis (PD) remains low despite arguments that support its greater use, including dialysis treatment away from hospital settings, avoidance of central venous catheters, and potential health economic advantag... Read More about International Variations in Peritoneal Dialysis Utilization and Implications for Practice.