Outputs (9)

Efficient and safe correction of hemophilia A by lentiviral vector-transduced BOECs in an implantable device (2021)
Journal Article

Hemophilia A (HA) is a rare bleeding disorder caused by deficiency/dysfunction of the FVIII protein. As current therapies based on frequent FVIII infusions are not a definitive cure, long-term expression of FVIII in endothelial cells through lentivir... Read More about Efficient and safe correction of hemophilia A by lentiviral vector-transduced BOECs in an implantable device.

The Use of Platelet-Rich Plasma (PRP) for the Management of Non-union Fractures (2021)
Journal Article

PURPOSE OF REVIEW: The treatment of non-union fractures represents a significant challenge for orthopaedic surgeons. In recent years, biologic agents have been investigated and utilised to support and improve bone healing. Among these agents, platele... Read More about The Use of Platelet-Rich Plasma (PRP) for the Management of Non-union Fractures.

Cryopreservation of Mesenchymal Stem Cells Using Medical Grade Ice Nucleation Inducer. (2020)
Journal Article

Mesenchymal stem cells (MSCs) can differentiate into multiple different tissue lineages and have favourable immunogenic potential making them an attractive prospect for regenerative medicine. As an essential part of the manufacturing process, preserv... Read More about Cryopreservation of Mesenchymal Stem Cells Using Medical Grade Ice Nucleation Inducer..

Platelet Rich Plasma as a Treatment Method for Rotator Cuff Tears (2020)
Journal Article

AbstractThe prevalence of the rotator cuff (RC) tears is ~?21% in the general population, with higher incidences in individuals over 50. Irrespective of surgical repair techniques employed, re-tear rates are alarmingly high, indicating the need for i... Read More about Platelet Rich Plasma as a Treatment Method for Rotator Cuff Tears.

Systematic Review of miRNA as Biomarkers in Alzheimer's Disease. (2019)
Journal Article

Currently there are 850,000 people with Alzheimer's disease in the UK, with an estimated rise to 1.1 million by 2025. Alzheimer's disease is characterised by the accumulation of amyloid-beta plaques and hyperphosphorylated tau in the brain causing a... Read More about Systematic Review of miRNA as Biomarkers in Alzheimer's Disease..

Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing. (2019)
Journal Article

There is a current need for a therapy that can alleviate the social and economic burden that presents itself with debilitating and recurring musculoskeletal soft tissue injuries and disorders. Currently, several therapies are emerging and undergoing... Read More about Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing..

A critical review of current progress in 3D kidney biomanufacturing: advances, challenges, and recommendations (2019)
Journal Article

The widening gap between organ availability and need is resulting in a worldwide crisis, particularly concerning kidney transplantation. Regenerative medicine options are becoming increasingly advanced and are taking advantage of progress in novel ma... Read More about A critical review of current progress in 3D kidney biomanufacturing: advances, challenges, and recommendations.

Rotator Cuff Repair Augmentation Using Osteoinductive Growth Factors (2019)
Journal Article

Rotator cuff injuries (RCIs) present a major health problem due to high incidences of degenerative tears greater than 3 cm and prevalence of re-tears following surgical procedures. Since healing and functional restoration relies upon bone ingrowth in... Read More about Rotator Cuff Repair Augmentation Using Osteoinductive Growth Factors.

Fabrication and characterization of 3D complex hydroxyapatite scaffolds with hierarchical porosity of different features for optimal bioactive performance (2017)
Journal Article

To improve the biological performance of hydroxyapatite scaffolds in bone tissue engineering, graphite was used as porogen to create additional micro/nanoporosity to macroporosity, resulting in hierarchical porosity. For maximum imitation of natural... Read More about Fabrication and characterization of 3D complex hydroxyapatite scaffolds with hierarchical porosity of different features for optimal bioactive performance.