Dietary phytochemicals against COVID‐19: A focus on thymoquinone
(2023)
Journal Article
Outputs (42)
Traditional processing techniques impacted the bioactivities of selected local consumed foods (2023)
Journal Article
Epidemiological and clinical studies have evidenced the crucial role of vegetables and mushrooms for our health. Vegetables and mushrooms are usually cooked before consumption which induces many physicochemical changes in foods. A change in the phyto... Read More about Traditional processing techniques impacted the bioactivities of selected local consumed foods.
Pluripharmacological potential of Mascarene endemic plant leaf extracts (2023)
Journal Article
In vivo antihyperglycaemic and antihyperlipidemic activities and chemical constituents of Solanum anomalum (2022)
Journal Article
Solanum anomalum is a plant used ethnomedically for the treatment of diabetes. The study was aimed to validate ethnomedical claims in rat model and identify the likely antidiabetic compounds. Leaf extract (70–210 mg/kg/day) and fractions (140 mg/kg/d... Read More about In vivo antihyperglycaemic and antihyperlipidemic activities and chemical constituents of Solanum anomalum.
Sesquiterpene Lactones Modulated DNA Methylation through Inhibition of DNMTs in Ovarian Cancer Cells (2022)
Journal Article
Inappropriate DNA methylation of tumour suppressor genes can affect their expression and function, and as such, DNA methylation has been a promising target for anti-cancer therapy. In gynaecological malignancy, ovarian cancer has the highest associat... Read More about Sesquiterpene Lactones Modulated DNA Methylation through Inhibition of DNMTs in Ovarian Cancer Cells.
In Vivo Antibacterial Efficacy of Antimicrobial Peptides Modified Metallic Implants-Systematic Review and Meta-Analysis. (2022)
Journal Article
Biomaterial-associated infection is difficult to detect and brings consequences that can lead to morbidity and mortality. Bacteria can adhere to the implant surface, grow, and form biofilms. Antimicrobial peptides (AMPs) can target and kill bacterial... Read More about In Vivo Antibacterial Efficacy of Antimicrobial Peptides Modified Metallic Implants-Systematic Review and Meta-Analysis..
Clerodane Diterpenoids from an Edible Plant Justicia insularis: Discovery, Cytotoxicity, and Apoptosis Induction in Human Ovarian Cancer Cells (2021)
Journal Article
Objectives: The toxicity of chemotherapeutic anticancer drugs is a serious issue in clinics. Drug discovery from edible and medicinal plants represents a promising approach towards finding safer anticancer therapeutics. Justicia insularis T. Anderson... Read More about Clerodane Diterpenoids from an Edible Plant Justicia insularis: Discovery, Cytotoxicity, and Apoptosis Induction in Human Ovarian Cancer Cells.
In vivo efficacy and metabolism of the antimalarial cycleanine and improved in vitro antiplasmodial activity of novel semisynthetic analogues. (2020)
Journal Article
Bisbenzylisoquinoline (BBIQ) alkaloids are a diverse group of natural products that demonstrate a range of biological activities. In this study, the in vitro antiplasmodial activity of three BBIQ alkaloids (cycleanine (1), isochondodendrine (2) and 2... Read More about In vivo efficacy and metabolism of the antimalarial cycleanine and improved in vitro antiplasmodial activity of novel semisynthetic analogues..
Methyl gallate – Rich fraction of Syzygium coriaceum leaf extract induced cancer cell cytotoxicity via oxidative stress (2020)
Journal Article
Whilst the pharmacological potential of Syzygium species is well reported in the literature, data on the Mauritian endemic Syzygium species is limited. Thus, the in vitro antioxidant and anti-proliferative properties of three endangered Syzygium spec... Read More about Methyl gallate – Rich fraction of Syzygium coriaceum leaf extract induced cancer cell cytotoxicity via oxidative stress.
Terminalia bentzoë, a Mascarene Endemic Plant, Inhibits Human Hepatocellular Carcinoma Cells Growth In Vitro via G0/G1 Phase Cell Cycle Arrest (2020)
Journal Article
Tropical forests constitute a prolific sanctuary of unique floral diversity and potential medicinal sources, however, many of them remain unexplored. The scarcity of rigorous scientific data on the surviving Mascarene endemic taxa renders bioprospect... Read More about Terminalia bentzoë, a Mascarene Endemic Plant, Inhibits Human Hepatocellular Carcinoma Cells Growth In Vitro via G0/G1 Phase Cell Cycle Arrest.