Skip to main content

Research Repository

Advanced Search

Outputs (158)

Bivalirudin, glycoprotein inhibitor and heparin use and association with outcomes of primary percutaneous coronary intervention in the United Kingdom (2015)
Journal Article

The HORIZONS trial reported a survival advantage for bivalirudin over heparin-with-glycoprotein inhibitors (GPIs) in primary PCI for ST elevation myocardial infarction. This drove an international shift in clinical practice. Subsequent studies have p... Read More about Bivalirudin, glycoprotein inhibitor and heparin use and association with outcomes of primary percutaneous coronary intervention in the United Kingdom.

Ambulatory heart rate range predicts mode-specific mortality and hospitalisation in chronic heart failure (2015)
Journal Article

Objective We aimed to define the prognostic value of the heart rate range during a 24 h period in patients with chronic heart failure (CHF). Methods Prospective observational cohort study of 791 patients with CHF associated with left ventricular s... Read More about Ambulatory heart rate range predicts mode-specific mortality and hospitalisation in chronic heart failure.

Primary care consultation rates among people with and without severe mental illness: a UK cohort study using the Clinical Practice Research Datalink. (2015)
Journal Article

OBJECTIVES: Little is known about service utilisation by patients with severe mental illness (SMI) in UK primary care. We examined their consultation rate patterns and whether they were impacted by the introduction of the Quality and Outcomes Framewo... Read More about Primary care consultation rates among people with and without severe mental illness: a UK cohort study using the Clinical Practice Research Datalink..

In Vivo Assessment of Bone Regeneration in Alginate/Bone ECM Hydrogels with Incorporated Skeletal Stem Cells and Single Growth Factors. (2015)
Journal Article

The current study has investigated the use of decellularised, demineralised bone extracellular matrix (ECM) hydrogel constructs for in vivo tissue mineralisation and bone formation. Stro-1-enriched human bone marrow stromal cells were incorporated to... Read More about In Vivo Assessment of Bone Regeneration in Alginate/Bone ECM Hydrogels with Incorporated Skeletal Stem Cells and Single Growth Factors..

Effect of age on the prognostic value of left ventricular function in patients with acute coronary syndrome: a prospective registry study (2015)
Journal Article

Objective: This study aims to study the prognostic impact of LV function on mortality and examine the effect of age on the prognostic value of left ventricular function. Methods: We examined the Myocardial Ischaemia National Audit Project (MINAP) reg... Read More about Effect of age on the prognostic value of left ventricular function in patients with acute coronary syndrome: a prospective registry study.

A systems-based investigation into vitamin D and skeletal muscle repair, regeneration, and hypertrophy (2015)
Journal Article

Skeletal muscle is a direct target for vitamin D. Observational studies suggest that low 25[OH]D correlates with functional recovery of skeletal muscle following eccentric contractions in humans and crush injury in rats. However, a definitive associa... Read More about A systems-based investigation into vitamin D and skeletal muscle repair, regeneration, and hypertrophy.

Inequalities in physical comorbidity: a longitudinal comparative cohort study of people with severe mental illness in the UK (2015)
Journal Article

Objectives Little is known about the prevalence of comorbidity rates in people with severe mental illness (SMI) in UK primary care. We calculated the prevalence of SMI by UK country, English region and deprivation quintile, antipsychotic and antidepr... Read More about Inequalities in physical comorbidity: a longitudinal comparative cohort study of people with severe mental illness in the UK.

The Concise Guide to PHARMACOLOGY 2015/16: Overview: The Concise Guide to PHARMACOLOGY 2015/16: Overview (2015)
Journal Article

The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.... Read More about The Concise Guide to PHARMACOLOGY 2015/16: Overview: The Concise Guide to PHARMACOLOGY 2015/16: Overview.

Differences in concentration of metal debris in blood, serum, and plasma samples of patients with metal-on-metal hip resurfacing arthroplasty (2015)
Journal Article

Background/aims Cobalt and chromium are released from MOM hips and their precise nature (ions/particles) is not known. Their distribution in serum, plasma, and whole blood may help to determine their nature. Methods We measured cobalt and chromi... Read More about Differences in concentration of metal debris in blood, serum, and plasma samples of patients with metal-on-metal hip resurfacing arthroplasty.