Outputs (2157)

Human vascularised synovium-on-a-chip: a mechanically stimulated, microfluidic model to investigate synovial inflammation and monocyte recruitment. (2023)
Journal Article
Thompson, C. L., Hopkins, T., Bevan, C., Screen, H. R., Wright, K. T., & Knight, M. M. (in press). Human vascularised synovium-on-a-chip: a mechanically stimulated, microfluidic model to investigate synovial inflammation and monocyte recruitment. Biomedical Materials, 18(6), https://doi.org/10.1088/1748-605X/acf976

Healthy synovium is critical for joint homeostasis. Synovial inflammation (synovitis) is implicated in the onset, progression and symptomatic presentation of arthritic joint diseases such as rheumatoid arthritis (RA) and osteoarthritis (OA). Thus, th... Read More about Human vascularised synovium-on-a-chip: a mechanically stimulated, microfluidic model to investigate synovial inflammation and monocyte recruitment..

Evaluating the use of electromyography in UK and european gait laboratories for the assessment of cerebral palsy and neurological conditions (2023)
Journal Article
Shepherd, H., Reeves, J., & Stewart, C. (in press). Evaluating the use of electromyography in UK and european gait laboratories for the assessment of cerebral palsy and neurological conditions. Gait & Posture, 106(S1), S170. https://doi.org/10.1016/j.gaitpost.2023.07.205

Introduction Electromyography (EMG) can estimate the magnitude and timing of muscle activation during walking in those with neurological gait disorders. Despite the potential of EMG use in assessment and clinical... Read More about Evaluating the use of electromyography in UK and european gait laboratories for the assessment of cerebral palsy and neurological conditions.

Percutaneous cruciate repair of ruptured Achilles tendon (2023)
Journal Article
Maffulli, N., Sammaria, G., Ziello, S., Migliorini, F., & Oliva, F. (in press). Percutaneous cruciate repair of ruptured Achilles tendon. Journal of Orthopaedic Surgery and Research, 18(1), https://doi.org/10.1186/s13018-023-04167-9

Percutaneous repair is a safe and reliable method to restore continuity after acute Achilles tendon ruptures, with a lower incidence of wound complications compared to open techniques. We describe a novel percutaneous cruciate suture performed throug... Read More about Percutaneous cruciate repair of ruptured Achilles tendon.

Evaluation of the introduction of a synchronous online induction for postgraduate diploma students. (2023)
Presentation / Conference
O'Byrne, R., & White, S. (2023, September). Evaluation of the introduction of a synchronous online induction for postgraduate diploma students. Poster presented at Pharmacy Education Conference 2023, Stopford building, Oxford road, The University of Manchester, UK

Background: A previous qualitative study identified the need for postgraduate clinical diploma distance-learning students to have a synchronous induction.(O’Byrne,2022) An induction session was created, starting in January 2022 for each new cohor... Read More about Evaluation of the introduction of a synchronous online induction for postgraduate diploma students..

Proteomic Profiling of Different Clinical Responses to Surgically Sustained and Acute Traumatic Cartilage Injuries (2023)
Presentation / Conference
Hulme, C., McDonald, J., Williams, A., Vincent, T. L., Watt, F. E., & Wright, K. (2023, September). Proteomic Profiling of Different Clinical Responses to Surgically Sustained and Acute Traumatic Cartilage Injuries. Paper presented at 17th ICRS World Congress 2023, Stiges, Barcelona, Spain

Total Nucleated Cell Count in Bone Marrow Aspirate Concentrate Does Not Predict the Proportion of Mesenchymal Stem Cells (2023)
Presentation / Conference
Wright, K., Makwana, N., Bing, A., Hulme, C., & McCarthy, H. (2023, September). Total Nucleated Cell Count in Bone Marrow Aspirate Concentrate Does Not Predict the Proportion of Mesenchymal Stem Cells. Paper presented at 17th ICRS World Congress 2023, Stiges, Barcelona, Spain

Analysis of Synovial Fluid Proteomes After Treating an Ovine Osteoarthritic Model with Human Umbilical Cord Mesenchymal Stem Cells (2023)
Presentation / Conference
McDonald, J., Wright, K., Mennan, C., Peffers, M., Perry, J., Roberts, S., …Hulme, C. (2023, September). Analysis of Synovial Fluid Proteomes After Treating an Ovine Osteoarthritic Model with Human Umbilical Cord Mesenchymal Stem Cells. Presented at International Cartilage and Joint Preservation Society World Congress 2023, Melia Hotel Sitges, Sitges/ Barcelona

TENDINopathy Severity Assessment – Achilles (TENDINS-A): Development and Content Validity Assessment of a New Patient-Reported Outcome Measure for Achilles Tendinopathy (2023)
Journal Article
Murphy, M. C., Newsham-West, R., Cook, J., Chimenti, R. L., de Vos, R., Maffulli, N., …Rio, E. K. (2024). TENDINopathy Severity Assessment – Achilles (TENDINS-A): Development and Content Validity Assessment of a New Patient-Reported Outcome Measure for Achilles Tendinopathy. Journal of Orthopaedic & Sports Physical Therapy, 54(1), 70-85. https://doi.org/10.2519/jospt.2023.11964

OBJECTIVE: To develop a new patient-reported outcome measure (PROM) assessing TENDINopathy Severity of the Achilles (TENDINS-Achilles) and evaluate its content validity. DESIGN: Mixed-methods, modified Delphi. METHODS: We performed 1 round of s... Read More about TENDINopathy Severity Assessment – Achilles (TENDINS-A): Development and Content Validity Assessment of a New Patient-Reported Outcome Measure for Achilles Tendinopathy.

Comparison of Knee Articular Cartilage Defect Size Between Measurements Obtained on Preoperative MRI Versus During Arthrotomy (2023)
Journal Article
Perry, J., Kuiper, J. H., McCarthy, H. S., Jermin, P., Gallacher, P. D., Tins, B., & Roberts, S. (2023). Comparison of Knee Articular Cartilage Defect Size Between Measurements Obtained on Preoperative MRI Versus During Arthrotomy. Orthopaedic Journal of Sports Medicine, 11(9), Article 23259671231193380. https://doi.org/10.1177/23259671231193380

Background: Treatment decisions for cartilage defects are often based on lesion size. Magnetic resonance imaging (MRI) is widely used to diagnose cartilage defects noninvasively; however, their size estimated from MRI may differ from defect sizes me... Read More about Comparison of Knee Articular Cartilage Defect Size Between Measurements Obtained on Preoperative MRI Versus During Arthrotomy.

Small interfering RNAs in the management of human osteoporosis (2023)
Journal Article
Gargano, G., Asparago, G., Spiezia, F., Oliva, F., & Maffulli, N. (2023). Small interfering RNAs in the management of human osteoporosis. British Medical Bulletin, 148(1), 58-69. https://doi.org/10.1093/bmb/ldad023

Background Osteoporosis results in reduced bone mass and consequent bone fragility. Small interfering RNAs (siRNAs) can be used for therapeutic purposes, as molecular targets or as useful markers to test new therapies. Sources of data A systemat... Read More about Small interfering RNAs in the management of human osteoporosis.