Outputs (2174)

THE KYNURENINE PATHWAY AND ITS ROLE IN GLIOBLASTOMA CELL MIGRATION (2023)
Journal Article
Sirnikova, D., Reynisson, J., Brüning-Richardson, A., & Kirby, C. (2023). THE KYNURENINE PATHWAY AND ITS ROLE IN GLIOBLASTOMA CELL MIGRATION. Neuro-Oncology, 25(Supplement_3), iii21-iii21. https://doi.org/10.1093/neuonc/noad147.091

AIMS The kynurenine (Kyn) pathway plays an important role in the pathogenesis of many cancers including glioblastomas (GBMs). The enzymes, indoleamine-2,3-dioxygenase (IDO1) and tryptophan-2,3-dioxygenase (TDO2), regulate the first and rate-limiting... Read More about THE KYNURENINE PATHWAY AND ITS ROLE IN GLIOBLASTOMA CELL MIGRATION.

Iron oxide nanoparticles as a new tool for treating cardiovascular diseases (2023)
Conference Proceeding
Cabrera, D., Ranjbar, J., Santana-Otero, A., Sharifabad, M. E., Ortega, D., Telling, N. D., & Harper, A. (2023). Iron oxide nanoparticles as a new tool for treating cardiovascular diseases. . https://doi.org/10.1109/intermagshortpapers58606.2023.10228198

Thrombotic events are a major cause of death and disability worldwide. Thrombolysis with the clot busting drug tissue plasminogen activator (tPA) or thromboprophylaxis using anticoagulants such as heparin are frontline treatments for thrombotic disea... Read More about Iron oxide nanoparticles as a new tool for treating cardiovascular diseases.

Subtalar joint axis alignments in pathological feet of children with cerebral palsy (2023)
Journal Article
Meilak, E., Wellenberg, R., Schallig, W., Roberts, A., Witbreuk, M., Buizer, A., …Stewart, C. (2023). Subtalar joint axis alignments in pathological feet of children with cerebral palsy. Gait & Posture, 106(S1), S122. https://doi.org/10.1016/j.gaitpost.2023.07.152

Introduction Children suffering cerebral palsy (CP) often develop foot deformities [1]. These manifest as pathological postures including equinovarus, planovalgus non-midfoot break (PNMFB) and midfoot break (MFB)... Read More about Subtalar joint axis alignments in pathological feet of children with cerebral palsy.

Quantifying morphological changes in middle trapezius with ultrasound scanning and a novel histogram matching algorithm (2023)
Journal Article
Philp, F., Meilak, E., Willis, T., Winn, N., & Pandyan, A. (in press). Quantifying morphological changes in middle trapezius with ultrasound scanning and a novel histogram matching algorithm. Gait & Posture, 106, S163-S164. https://doi.org/10.1016/j.gaitpost.2023.07.197

Introduction Facioscapulohumeral dystrophy (FSHD) can affect upper-limb function through muscle degeneration, fatty infiltration and oedema. Muscle echogenicity, measured using ultrasound, could be used as a bioma... Read More about Quantifying morphological changes in middle trapezius with ultrasound scanning and a novel histogram matching algorithm.

Evaluating the use of electromyography in UK and european gait laboratories for the assessment of cerebral palsy and neurological conditions (2023)
Journal Article
Shepherd, H., Reeves, J., & Stewart, C. (in press). Evaluating the use of electromyography in UK and european gait laboratories for the assessment of cerebral palsy and neurological conditions. Gait & Posture, 106(S1), S170. https://doi.org/10.1016/j.gaitpost.2023.07.205

Introduction Electromyography (EMG) can estimate the magnitude and timing of muscle activation during walking in those with neurological gait disorders. Despite the potential of EMG use in assessment and clinical... Read More about Evaluating the use of electromyography in UK and european gait laboratories for the assessment of cerebral palsy and neurological conditions.

Tendon tissue engineering: An overview of biologics to promote tendon healing and repair (2023)
Journal Article
Citro, V., Clerici, M., Boccaccini, A. R., Della Porta, G., Maffulli, N., & Forsyth, N. R. (2023). Tendon tissue engineering: An overview of biologics to promote tendon healing and repair. Journal of Tissue Engineering,

Tendons are dense connective tissues with a hierarchical polarized structure that respond to and adapt to the transmission of muscle contraction forces to the skeleton, enabling motion and maintaining posture. Tendon injuries, also known as tendinopa... Read More about Tendon tissue engineering: An overview of biologics to promote tendon healing and repair.

Subtalar joint moments of children with cerebral palsy (2023)
Journal Article
Meilak, E., Modenese, L., Andrew, R., Julie, S., Edward, C., & Stewart, C. (in press). Subtalar joint moments of children with cerebral palsy. Gait & Posture, 106, S121. https://doi.org/10.1016/j.gaitpost.2023.07.151

Introduction Children with cerebral palsy (CP) often develop foot deformities [1], such as equinovarus, planovalgus non-midfoot break (PNMFB) and midfoot break (MFB) [2]. The aetiology of the development and progr... Read More about Subtalar joint moments of children with cerebral palsy.

Human vascularised synovium-on-a-chip: a mechanically stimulated, microfluidic model to investigate synovial inflammation and monocyte recruitment. (2023)
Journal Article
Thompson, C. L., Hopkins, T., Bevan, C., Screen, H. R., Wright, K. T., & Knight, M. M. (in press). Human vascularised synovium-on-a-chip: a mechanically stimulated, microfluidic model to investigate synovial inflammation and monocyte recruitment. Biomedical Materials, 18(6), https://doi.org/10.1088/1748-605X/acf976

Healthy synovium is critical for joint homeostasis. Synovial inflammation (synovitis) is implicated in the onset, progression and symptomatic presentation of arthritic joint diseases such as rheumatoid arthritis (RA) and osteoarthritis (OA). Thus, th... Read More about Human vascularised synovium-on-a-chip: a mechanically stimulated, microfluidic model to investigate synovial inflammation and monocyte recruitment..

Percutaneous cruciate repair of ruptured Achilles tendon (2023)
Journal Article
Maffulli, N., Sammaria, G., Ziello, S., Migliorini, F., & Oliva, F. (in press). Percutaneous cruciate repair of ruptured Achilles tendon. Journal of Orthopaedic Surgery and Research, 18(1), https://doi.org/10.1186/s13018-023-04167-9

Percutaneous repair is a safe and reliable method to restore continuity after acute Achilles tendon ruptures, with a lower incidence of wound complications compared to open techniques. We describe a novel percutaneous cruciate suture performed throug... Read More about Percutaneous cruciate repair of ruptured Achilles tendon.

Evaluation of the introduction of a synchronous online induction for postgraduate diploma students. (2023)
Presentation / Conference
O'Byrne, R., & White, S. (2023, September). Evaluation of the introduction of a synchronous online induction for postgraduate diploma students. Poster presented at Pharmacy Education Conference 2023, Stopford building, Oxford road, The University of Manchester, UK

Background: A previous qualitative study identified the need for postgraduate clinical diploma distance-learning students to have a synchronous induction.(O’Byrne,2022) An induction session was created, starting in January 2022 for each new cohor... Read More about Evaluation of the introduction of a synchronous online induction for postgraduate diploma students..