Outputs (4)

Conical shell X-ray beam tomosynthesis and micro-computed tomography for microarchitectural characterisation (2023)
Journal Article
Arnold, E. L., Elarnaut, F., Downes, D., Evans, J. P. O., Greenwood, C., & Rogers, K. D. (in press). Conical shell X-ray beam tomosynthesis and micro-computed tomography for microarchitectural characterisation. Scientific Reports, 13(1), Article 21480. https://doi.org/10.1038/s41598-023-48851-6

Bone quality is commonly used to diagnose bone diseases such as osteoporosis, with many studies focusing on microarchitecture for fracture prediction. In this study a bovine distal femur was imaged using both micro-computed tomography (µCT) and tomos... Read More about Conical shell X-ray beam tomosynthesis and micro-computed tomography for microarchitectural characterisation.

A pilot study: effect of irisin on trabecular bone in a streptozotocin-induced animal model of type 1 diabetic osteopathy utilizing a micro-CT (2023)
Journal Article
Mohsin, S., Brock, F., Kaimala, S., Greenwood, C., Sulaiman, M., Rogers, K., & Adeghate, E. (in press). A pilot study: effect of irisin on trabecular bone in a streptozotocin-induced animal model of type 1 diabetic osteopathy utilizing a micro-CT. PeerJ, 11, Article e16278. https://doi.org/10.7717/peerj.16278

Background: Osteoporosis is a significant co-morbidity of type 1 diabetes mellitus (DM1) leading to increased fracture risk. Exercise-induced hormone ‘irisin’ in low dosage has been shown to have a beneficial effect on bone metabolism by increasing o... Read More about A pilot study: effect of irisin on trabecular bone in a streptozotocin-induced animal model of type 1 diabetic osteopathy utilizing a micro-CT.

Microcalcification crystallography as a potential marker of DCIS recurrence (2023)
Journal Article
Gosling, S. B., Arnold, E. L., Davies, S. K., Cross, H., Bouybayoune, I., Calabrese, D., …van Oirsouw, M. (2023). Microcalcification crystallography as a potential marker of DCIS recurrence. Scientific reports, 13(1), Article 9331. https://doi.org/10.1038/s41598-023-33547-8

Ductal carcinoma in-situ (DCIS) accounts for 20-25% of all new breast cancer diagnoses. DCIS has an uncertain risk of progression to invasive breast cancer and a lack of predictive biomarkers may result in relatively high levels (~ 75%) of overtreatm... Read More about Microcalcification crystallography as a potential marker of DCIS recurrence.

Exploration of utility of combined optical photothermal infrared and Raman imaging for investigating the chemical composition of microcalcifications in breast cancer (2023)
Journal Article
Bouzy, P., Lyburn, I. D., Pinder, S. E., Scott, R., Mansfield, J., Moger, J., …Stone, N. (in press). Exploration of utility of combined optical photothermal infrared and Raman imaging for investigating the chemical composition of microcalcifications in breast cancer. Analytical Methods, 15(13), 1620-1630. https://doi.org/10.1039/d2ay01197b

Microcalcifications play an important role in cancer detection. They are evaluated by their radiological and histological characteristics but it is challenging to find a link between their morphology, their composition and the nature of a specific ty... Read More about Exploration of utility of combined optical photothermal infrared and Raman imaging for investigating the chemical composition of microcalcifications in breast cancer.