Outputs (22)

Establishing a minimum PMI for bone sun bleaching in a UK environment with a controlled desert-simulated comparison (2020)
Journal Article
Stokes, S., Greenwood, C., & Márquez-Grant, N. (2020). Establishing a minimum PMI for bone sun bleaching in a UK environment with a controlled desert-simulated comparison. International Journal of Legal Medicine, 134, 2297–2306. https://doi.org/10.1007/s00414-020-02385-y

Microenvironments play a significant part in understanding the post-mortem interval in forensic taphonomy. Recently, the value of weathering factors in relation to obtaining a PMI has been investigated further. In this study, observations were made t... Read More about Establishing a minimum PMI for bone sun bleaching in a UK environment with a controlled desert-simulated comparison.

Age-Related Trends in the Trabecular Micro-Architecture of the Medial Clavicle: Is It of Use in Forensic Science? (2020)
Journal Article
McGivern, H., Greenwood, C., Márquez-Grant, N., Kranioti, E., Xhemali, B., & Zioupos, P. (2020). Age-Related Trends in the Trabecular Micro-Architecture of the Medial Clavicle: Is It of Use in Forensic Science?. Frontiers in Bioengineering and Biotechnology, 7, https://doi.org/10.3389/fbioe.2019.00467

The mechanical and structural properties of bone are known to change significantly with age. Within forensic and archaeological investigations, the medial end of the clavicle is typically used for estimating the age-at-death of an unknown individual.... Read More about Age-Related Trends in the Trabecular Micro-Architecture of the Medial Clavicle: Is It of Use in Forensic Science?.

The use of µCT and fractal dimension for fracture prediction in osteoporotic individuals (2019)
Journal Article
Arnold, E., Clement, J., Rogers, K., Garcia-Castro, F., & Greenwood, C. (2020). The use of µCT and fractal dimension for fracture prediction in osteoporotic individuals. Journal of the Mechanical Behavior of Biomedical Materials, 103, Article 103585. https://doi.org/10.1016/j.jmbbm.2019.103585

Osteoporosis (OP) is a widespread condition with commonly associated fracture sites at the hip, vertebra and wrist. This study examines the effects of age and osteoporosis on bone quality by comparing the efficacy of using parameters which indicate b... Read More about The use of µCT and fractal dimension for fracture prediction in osteoporotic individuals.

Breast Microcalcifications - Novel Biomarkers for Breast Tissue Pathology (2019)
Journal Article
Gosling, S., Scott, R., Greenwood, C., Bouzy, P., Nallala, J., Lyburn, I., …Rogers, K. (2019). Breast Microcalcifications - Novel Biomarkers for Breast Tissue Pathology. Breast Cancer Research, 21(S1),

Microcalcifications are a key feature of mammography. Calcium phosphate (hydroxyapatite) microcalcifications are associated with both benign and malignant breast tissue and spectroscopic analysis has previously shown microstructure and chemistry vari... Read More about Breast Microcalcifications - Novel Biomarkers for Breast Tissue Pathology.

Calcification Microstructure Reflects Breast Tissue Microenvironment (2019)
Journal Article
Gosling, S., Scott, R., Greenwood, C., Bouzy, P., Nallala, J., D. Lyburn, I., …Rogers, K. (2019). Calcification Microstructure Reflects Breast Tissue Microenvironment. Journal of Mammary Gland Biology and Neoplasia, 333-342. https://doi.org/10.1007/s10911-019-09441-3

Microcalcifications are important diagnostic indicators of disease in breast tissue. Tissue microenvironments differ in many aspects between normal and cancerous cells, notably extracellular pH and glycolytic respiration. Hydroxyapatite microcalcific... Read More about Calcification Microstructure Reflects Breast Tissue Microenvironment.

Age Related Changes in Femoral Head Trabecular Architecture (2018)
Journal Article
Greenwood, C., Clement, J., Dicken, A., Evans, J., Lyburn, I., Martin, R., …Rogers, K. (2018). Age Related Changes in Femoral Head Trabecular Architecture. Aging and Disease, 9(6), 976-987. https://doi.org/10.14336/AD.2018.0124

Osteoporosis is a prevalent bone condition, characterised by low bone mineral density and increased fracture risk. Currently, the gold standard for identifying osteoporosis and increased fracture risk is through quantification of bone mineral density... Read More about Age Related Changes in Femoral Head Trabecular Architecture.

Towards Medical Diagnostics Using Hyperspectral X-ray scatter (2017)
Conference Proceeding
Greenwood, C., Rogers, K., Wilson, M., Lyburn, I., Evans, P., & Davies, G. (2017). Towards Medical Diagnostics Using Hyperspectral X-ray scatter.

This pilot study builds from a recent international, programme that showed, for the first time, the clinical value of new biomarkers to predict fracture risk in osteoporotic patients. The research indicated several potential, high impact routes towar... Read More about Towards Medical Diagnostics Using Hyperspectral X-ray scatter.

Towards new material biomarkers for fracture risk (2016)
Journal Article
Greenwood, C., Clement, J., Dicken, A., Evans, J., Lyburn, I., Martin, R., …Zioupos, P. (2016). Towards new material biomarkers for fracture risk. BONE, 93, 55-63. https://doi.org/10.1016/j.bone.2016.09.006

Osteoporosis is a prevalent bone condition, characterised by low bone mass and increased fracture risk. Currently, the gold standard for identifying osteoporosis and increased fracture risk is through quantification of bone mineral density (BMD) usin... Read More about Towards new material biomarkers for fracture risk.

Classification of fracture and non-fracture groups by analysis of coherent X-ray scatter (2016)
Journal Article
Dicken, A., Evans, J., Rogers, K., Stone, N., Greenwood, C., Godber, S., …Zioupos, P. (2016). Classification of fracture and non-fracture groups by analysis of coherent X-ray scatter. Scientific reports, 6, Article 29011. https://doi.org/10.1038/srep29011

Osteoporotic fractures present a significant social and economic burden, which is set to rise
commensurately with the aging population. Greater understanding of the physicochemical differences
between osteoporotic and normal conditions will facilit... Read More about Classification of fracture and non-fracture groups by analysis of coherent X-ray scatter.

The micro-architecture of human cancellous bone from fracture neck of femur patients in relation to the structural integrity and fracture toughness of the tissue (2015)
Journal Article
Greenwood, C., Clement, J., Dicken, A., Evans, J., Lyburn, I., Martin, R., …Zioupos, P. (2015). The micro-architecture of human cancellous bone from fracture neck of femur patients in relation to the structural integrity and fracture toughness of the tissue. Bone Reports, 3, 67 - 75. https://doi.org/10.1016/j.bonr.2015.10.001

Osteoporosis is clinically assessed from bone mineral density measurements using dual energy X-ray absorption (DXA). However, these measurements do not always provide an accurate fracture prediction, arguably because DXA does not grapple with ‘bone q... Read More about The micro-architecture of human cancellous bone from fracture neck of femur patients in relation to the structural integrity and fracture toughness of the tissue.