Outputs (4)

Collagenase Biosensor Based on the Degradation of Peptide Cross-Linked Poly(Ethylene Glycol) Hydrogel Films (2018)
Conference Proceeding
Ahmad, N., Colak, B., Gibbs, M. J., Zhang, D., Becer, C. R., Watkinson, M., …Krause, S. Collagenase Biosensor Based on the Degradation of Peptide Cross-Linked Poly(Ethylene Glycol) Hydrogel Films. . https://doi.org/10.3390/proceedings2130961

Peptide cross-linked poly(ethylene glycol) hydrogel is a promising biomaterial that has been used widely for drug delivery and tissue engineering. However, the use of this material as a biosensor material for the detection of collagenase has not been... Read More about Collagenase Biosensor Based on the Degradation of Peptide Cross-Linked Poly(Ethylene Glycol) Hydrogel Films.

Biotin-tagged fluorescent sensor to visualize 'mobile' Zn2+ in cancer cells (2018)
Journal Article
Watkinson. (2018). Biotin-tagged fluorescent sensor to visualize 'mobile' Zn2+ in cancer cells. Chemical Communications, 9619-9266. https://doi.org/10.1039/c8cc05425h

A cancer cell-targeting fluorescent sensor has been developed to image mobile Zn2+ by introducing a biotin group. It shows a highly selective response to Zn2+ in vitro, no toxicity in cellulo and images 'mobile' Zn2+ specifically in cancer cells. We... Read More about Biotin-tagged fluorescent sensor to visualize 'mobile' Zn2+ in cancer cells.

Chelating Rotaxane Ligands as Fluorescent Sensors for Metal Ions (2018)
Journal Article
Watkinson. (2018). Chelating Rotaxane Ligands as Fluorescent Sensors for Metal Ions. Angewandte Chemie, 5310-5314. https://doi.org/10.1002/anie.201712931

Although metal-ion-binding interlocked molecules have been under intense investigation for over three decades, their application as scaffolds for the development of sensors for metal ions remains underexplored. In this work, we demonstrate the potent... Read More about Chelating Rotaxane Ligands as Fluorescent Sensors for Metal Ions.

Remarkable increase in the rate of the catalytic epoxidation of electron deficient styrenes through the addition of Sc(OTf)3 to the MnTMTACN catalyst. (2018)
Journal Article
Watkinson. (2018). Remarkable increase in the rate of the catalytic epoxidation of electron deficient styrenes through the addition of Sc(OTf)3 to the MnTMTACN catalyst. Chemical Communications, 1461 -1464. https://doi.org/10.1039/C7CC09698D

The effect of Lewis acids on the catalytic activity of [Mn2(µ-O)3(TMTACN)2](PF6)2 in the epoxidation of styrenes using hydrogen peroxide as the oxidant has shown that the addition of Sc(OTf)3 at low catalytic loading results in a very significant inc... Read More about Remarkable increase in the rate of the catalytic epoxidation of electron deficient styrenes through the addition of Sc(OTf)3 to the MnTMTACN catalyst..