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Case-Control Study of Risk Factors for Sporadic Giardiasis and Parasite Assemblages in North West England (2015)
Journal Article
(2015). Case-Control Study of Risk Factors for Sporadic Giardiasis and Parasite Assemblages in North West England. Journal of Clinical Microbiology, 3133 - 3140. https://doi.org/10.1128/JCM.00715-15

Giardia duodenalis is a major cause of infectious gastroenteritis worldwide, and it is diversified into eight genetic assemblages (A to H), which are distinguishable only by molecular typing. There is some evidence that the assemblages infecting huma... Read More about Case-Control Study of Risk Factors for Sporadic Giardiasis and Parasite Assemblages in North West England.

Bumblebee pupae contain high levels of aluminium (2015)
Journal Article
(2015). Bumblebee pupae contain high levels of aluminium. PloS one, e0127665 - ?. https://doi.org/10.1371/journal.+pone.0127665

The causes of declines in bees and other pollinators remains an on-going debate. While recent attention has focussed upon pesticides, other environmental pollutants have largely been ignored. Aluminium is the most significant environmental contaminan... Read More about Bumblebee pupae contain high levels of aluminium.

A large-scale proteogenomics study of apicomplexan pathogens-Toxoplasma gondii and Neospora caninum (2015)
Journal Article
(2015). A large-scale proteogenomics study of apicomplexan pathogens-Toxoplasma gondii and Neospora caninum. Proteomics, 2618 -2628. https://doi.org/10.1002/pmic.201400553

Proteomics data can supplement genome annotation efforts, for example being used to confirm gene models or correct gene annotation errors. Here, we present a large-scale proteogenomics study of two important apicomplexan pathogens: Toxoplasma gondii... Read More about A large-scale proteogenomics study of apicomplexan pathogens-Toxoplasma gondii and Neospora caninum.

X-Ray Crystal Structure and Properties of Phanta, a Weakly Fluorescent Photochromic GFP-Like Protein (2015)
Journal Article
(2015). X-Ray Crystal Structure and Properties of Phanta, a Weakly Fluorescent Photochromic GFP-Like Protein. PloS one, e0123338 - e0123338. https://doi.org/10.1371/journal.pone.0123338

Phanta is a reversibly photoswitching chromoprotein (FF, 0.003), useful for pcFRET, that was isolated from a mutagenesis screen of the bright green fluorescent eCGP123 (FF, 0.8). We have investigated the contribution of substitutions at positions His... Read More about X-Ray Crystal Structure and Properties of Phanta, a Weakly Fluorescent Photochromic GFP-Like Protein.

Al adjuvants can be tracked in viable cells by lumogallion (2015)
Journal Article
(2015). Al adjuvants can be tracked in viable cells by lumogallion. Journal of Immunological Methods, 87-94. https://doi.org/10.1016/j.jim.2015.04.008

The mechanism behind the adjuvant effect of aluminum salts is poorly understood notwithstanding that aluminum salts have been used for decades in clinical vaccines. In an aqueous environment and at a nearly neutral pH, the aluminum salts form particu... Read More about Al adjuvants can be tracked in viable cells by lumogallion.

Experimental swap of anopheles gambiae's assortative mating preferences demonstrates key role of X-chromosome divergence island in incipient sympatric speciation (2015)
Journal Article
(2015). Experimental swap of anopheles gambiae's assortative mating preferences demonstrates key role of X-chromosome divergence island in incipient sympatric speciation. PLOS genetics, https://doi.org/10.1371/journal.pgen.1005141

Although many theoretical models of sympatric speciation propose that genes responsible for assortative mating amongst incipient species should be associated with genomic regions protected from recombination, there are few data to support this theory... Read More about Experimental swap of anopheles gambiae's assortative mating preferences demonstrates key role of X-chromosome divergence island in incipient sympatric speciation.

Local mechanisms for loud sound-enhanced aminoglycoside entry into outer hair cells. (2015)
Journal Article
(2015). Local mechanisms for loud sound-enhanced aminoglycoside entry into outer hair cells. Frontiers in Cellular Neuroscience, 130 - ?. https://doi.org/10.3389/fncel.2015.00130

Loud sound exposure exacerbates aminoglycoside ototoxicity, increasing the risk of permanent hearing loss and degrading the quality of life in affected individuals. We previously reported that loud sound exposure induces temporary threshold shifts (T... Read More about Local mechanisms for loud sound-enhanced aminoglycoside entry into outer hair cells..

Comprehensive evaluation of Toxoplasma gondii VEG and Neospora caninum LIV genomes with tachyzoite stage transcriptome and proteome defines novel transcript features. (2015)
Journal Article
(2015). Comprehensive evaluation of Toxoplasma gondii VEG and Neospora caninum LIV genomes with tachyzoite stage transcriptome and proteome defines novel transcript features. PloS one, e0124473 - ?. https://doi.org/10.1371/journal.pone.0124473

Toxoplasma gondii is an important protozoan parasite that infects all warm-blooded animals and causes opportunistic infections in immuno-compromised humans. Its closest relative, Neospora caninum, is an important veterinary pathogen that causes spont... Read More about Comprehensive evaluation of Toxoplasma gondii VEG and Neospora caninum LIV genomes with tachyzoite stage transcriptome and proteome defines novel transcript features..

Astrocyte and Neuronal Plasticity in the Somatosensory System (2015)
Journal Article
Sims, R. E., Butcher, J. B., Rheinallt Parri, H., & Glazewski, S. (2015). Astrocyte and Neuronal Plasticity in the Somatosensory System. Neural Plasticity, 2015, Article 732014. https://doi.org/10.1155/2015/732014

Changing the whisker complement on a rodent’s snout can lead to two forms of experience-dependent plasticity (EDP) in the neurons of the barrel cortex, where whiskers are somatotopically represented. One form, termed coding plasticity, concerns chang... Read More about Astrocyte and Neuronal Plasticity in the Somatosensory System.