Impact of Decision Aids on Screening Prostate Cancer: A Systematic Review with a Meta-Analysis

Adeli, Mahin; Zayeri, Farid; Rasekhi, Ali Akbar; Kiani, Zahra; Amini, Payam

Abstract

Abstract
Background and Objectives: Prostate cancer is the most common solid cancer and there are different findings about the effect of decision aids (DAs) on the amount of screening with prostate-specific antigen (PSA). Therefor this study investigated the impact of decision aids on prostate-specific antigen screening for prostate cancer.

Methods: We searched the articles published in English until August 18, 2024. In all studies, the independent variable was DAs and the response was the PSA test and the relationship index evaluate was the risk ratio (RR). The random-effects meta-analysis and subgroup analysis for response and follow-up times were performed.

Results: In this review, 11 studies (N = 8983) were selected. Egger (P = 0.05) and Begg (P = 0.09) tests showed the absence of publication bias. The random-effects model showed decrease of 9% PSA test in the DAs group compared with control group (RR = 0.91, 95% CI = 0.71-1.16) but there was no statistically significant difference in prostate cancer screening between two groups. Subgroup analysis of the response variable, 1- Doing by reviewing the medical report (P = 0.86, 95% CI = 0.6-1.24), 2- Intention to do (P = 0.88, 95% CI = 0.61-1.28) and 3- Doing the self-report (P = 1.13, 95% CI = 0.67-1.91), showed that there was no statistically significant relationship between the DAs and the PSA test. Subgroup analysis of the follow-up period of fewer than 4 months (P = 0.98, 95% CI = 0.71-1.52) and more than 4 months (P = 0.91, 95% CI = 0.62-1.35) showed no statistically significant relationship between the DAs and the PSA test.

Conclusion: In general, our findings revealed that the informed DAs has no significant impact on PSA test behavior. Considering the importance of the PSA test, it is recommended to strengthen the relationship between the patient -physician about the test and its benefits.

Citation

Adeli, M., Zayeri, F., Rasekhi, A. A., Kiani, Z., & Amini, P. (2024). Impact of Decision Aids on Screening Prostate Cancer: A Systematic Review with a Meta-Analysis. Iranian Red Crescent Medical Journal, 26(1), 1-9. https://doi.org/10.22034/ircmj.2024.203979

• Journal Article Type: Article
• Acceptance Date: Aug 31, 2024
• Online Publication Date: Aug 31, 2024
• Publication Date: Oct 14, 2024
• Deposit Date: Jan 24, 2025
• Journal: Iranian Red Crescent Medical Journal (IRCM)
• Print ISSN: 1561-4395
• Electronic ISSN: 2074-1812
• Publisher: Iranian Red Crescent Medical Journal
• Peer Reviewed: Peer Reviewed
• Volume: 26
• Issue: 1
• Article Number: 203979
• Pages: 1-9
• DOI: https://doi.org/10.22034/ircmj.2024.203979
• Keywords: Meta-Analysis, Relative Risk, Prostate Cancer, Cancer Screening, Decision Aids, Prostate-Specific Antigen
• Public URL: https://keele-repository.worktribe.com/output/1051375